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CPT 81529 Fee Schedule

Last Verified: October 2026

Healthcare providers use this code to document and receive reimbursement for visits that address high-level medical decision-making, often including multiple diagnoses or prescription management.

Onc Cutan Mlnma Mrna 31 Gene, Oncology Cutaneous Melanoma Mrna Gene Expression Profiling By Real Time Rt Pcr Of 31 Genes 28 Content And 3 Housekeeping Utilizing Formalin Fixed Paraffin Embedded Tissue Algorithm Reported As Recurrence Risk Including Likelihood Of Sentinel Lymph Node Metastasis
Key FactDetail
Service Type

Pathology and Laboratory Procedures

Multianalyte Assays with Algorithmic Analyses

Common Place of Service

81 - Independent Laboratory

Common Modifiers

59 - Distinct Procedural Service

Complexity LevelHigh
Medicare Fee Schedule$7,193.00 national lab fee schedule rate (2026) · View Medicare rates for 81529
Medicaid Fee Schedule$7,121.065 median of the 8 states in the free preview · View Medicaid rates for 81529

National average reimbursement for CPT 81529 by major payers:

bcbs

$5,827.53

uhc

$4,404.63

aetna

$6,508.51

cigna

$10,252.77

Compare published rates across providers.

Choose a payer to see a sample of rates for CPT 81529.

CPT 81529
5 of 25 sample ratesHigher to lower in this preview
  1. Chu Chen

    Merrimack Valley Pediatric Associates, Inc.

    MAPediatrics PhysicianNPI 1073502985Tax ID 42-484572

    $15,824.60Published rate
  2. Christopher Raio

    Mercy Medical Center

    NYEmergency Medicine PhysicianNPI 1255478004Tax ID 11-1635088

    $9,494.76Published rate
  3. Baycare Home Care, Inc.

    Baycare Home Care Inc

    FLHome Health AgencyNPI 1821097627Tax ID 59-3582520

    $5,304.41Published rate
  4. Christopher Raio

    St Francis Hospital

    NYEmergency Medicine PhysicianNPI 1255478004Tax ID 11-2050523

    $3,884.22Published rate
  5. Sunrise Home Health Care Inc.

    Sunrise Home Health Care Inc

    FLHome Health AgencyNPI 1366400376Tax ID 65-0307774

    $2,877.19Published rate

National sample. Rates vary by location, specialty, and contract.

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CPT 81529 vs. Other Multianalyte Assays with Algorithmic Analyses Codes

The CPT 81529 code is part of the Pathology and Laboratory Procedures services used for Multianalyte Assays with Algorithmic Analyses. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The CPT 81529 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
81525-CPTHighPathology Panel/Obstetric, Oncology (Colon) Mrna Gene Expression Profiling By Real-Time Rt-Pcr Of 12 Genes (7 Content And 5 Housekeeping) Utilizing Formalin-Fixed Paraffin-Embedded Tissue Algorithm Reported As A Recurrence Score
81528-CPTModerateCologuard-Oncology (Colorectal, Cologuard-Oncology (Colorectal) Screening Quantitative Real-Time Target And Signal Amplification Of10 Dna Markers (Kras Mutations Promoter Methylat Ion Of Ndrg4 And Bmp3) And Fecal Hemoglobin Utilizing Stool Algorithm Reported As A Positive Or Negative Result
81529-CPTHighOnc Cutan Mlnma Mrna 31 Gene, Oncology Cutaneous Melanoma Mrna Gene Expression Profiling By Real Time Rt Pcr Of 31 Genes 28 Content And 3 Housekeeping Utilizing Formalin Fixed Paraffin Embedded Tissue Algorithm Reported As Recurrence Risk Including Likelihood Of Sentinel Lymph Node Metastasis
81535-CPTModerateOncology (Gynecologic) Live T, Oncology (Gynecologic) Live Tumor Cell Culture And Chemotherapeutic Response By Dapi Stain And Morphology Predictive Algorithm Reported As A Drug Response Score First Single Drug Or Drug Combinatio

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 81529. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 81529 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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