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HCPCS C5278 Fee Schedule

Last Verified: February 2026

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Application of low cost skin substitute graft to face, scalp, eyelids, mouth, neck, ears, orbits, genitalia, hands, feet, and/or multiple digits, total wound surface area greater than or equal to 100 sq cm; each additional 100 sq cm wound surface area, or part thereof, or each additional 1% of body area of infants and children, or part thereof (list separately in addition to code for primary procedure)
Key FactDetail
Service Type

Outpatient PPS

Skin Substitute Graft Application

Complexity LevelLow

National average reimbursement for HCPCS C5278 by major payers:

bcbs

$22.94

uhc

$54.00

aetna

$49.42

cigna

$N/A

Preview provider-level rates for...
For billing codeHCPCS C5278
PayerCodeRateNPITax IDStateSpecialty

Select a payer to view fee schedule data

Choose a payer from the options above to see rates for HCPCS C5278

United
C5278$1191.001104819366 - CHILDREN'S HOSPITAL720467503 - CHILDRENS HOSPITAL INCLAChildren's Hospital (282NC2000X)
United
C5278$2278.001225050396 - NORTHSIDE HOSPITAL, INC., NORTHSIDE HOSPITAL CHEROKEE581954432 - (GA) NORTHSIDE HOSPITAL INCGAGeneral Acute Care Hospital (282N00000X)
United
C5278$525.001215194204 - ALLEN PARISH HOSPITAL DISTRICT NO 3, ALLEN PARISH HOSPITAL720655439LAGeneral Acute Care Hospital (282N00000X)
United
C5278$525.001215194204 - ALLEN PARISH HOSPITAL DISTRICT NO 3, ALLEN PARISH HOSPITAL720655439LAGeneral Acute Care Hospital (282N00000X)
United
C5278$1858.001285663856 - ROCKDALE MEDICAL CENTER INC., ROCKDALE HOSPITAL300999841 - (GA) PIEDMONT ROCKDALE HOSPITAL INCGAGeneral Acute Care Hospital (282N00000X)
United
C5278$1858.001811940976 - MACON NORTHSIDE HOSPITAL, LLC, PIEDMONT MACON NORTH HOSPITAL621736985 - (GA) MACON NORTHSIDE HOSPITAL LLCGAGeneral Acute Care Hospital (282N00000X)
United
C5278$177.001285835561 - BIENVILLE MEDICAL CENTER INC743227578LACritical Access Hospital (282NC0060X)
United
C5278$723.001649488511 - TOURO INFIRMARY ANESTHESIA SERVICES720423659 - (LA) TOURO INFIRMARYLAGeneral Acute Care Hospital (282N00000X)
United
C5278$1409.001801299375 - OCHSNER MEDICAL CENTER, OCHSNER MEDICAL COMPLEX - RIVER PARISHES205432782LACritical Access Hospital (282NC0060X)
United
C5278$495.001588631311 - SURGICAL SPECIALTY CENTER OF BATON ROUGE, LLC, SURGICAL SPECIALTY CENTER OF BATON ROUGE263120962 - (LA) SURGICAL SPECIALTY CENTER OF BATON ROUGE, LLCLAGeneral Acute Care Hospital (282N00000X)
United
C5278$79.001144216847 - RIVER PARK ASC LLC721510504 - (LA) RIVER PARK ASC LLCLAAmbulatory Surgical Clinic/Center (261QA1903X)
United
C5278$555.001104181247 - ADVANCED SURGERY CENTER OF NORTHERN LOUISIANA LLC455502071 - (LA) ADVANCED SURGERY CENTER OF NORTHERN LOUISIANA, LLCLAAmbulatory Surgical Clinic/Center (261QA1903X)
United
C5278$1082.001437186111 - PIEDMONT ATHENS REGIONAL MEDICAL CENTER, INC.582179986 - (GA) PIEDMONT ATHENS REGIONAL MEDICAL CENTER INCGAGeneral Acute Care Hospital (282N00000X)
United
C5278$100.001255911970 - PINNACLE SURGERY CENTER842367400 - (LA) PINNACLE SURGERY CENTERLAAmbulatory Surgical Clinic/Center (261QA1903X)
United
C5278$434.001114929957 - OPHTHALMIC OUTPATIENT SURGERY CENTER PARTNERS, LLC, OUTPATIENT SURGERY CENTER FOR SIGHT721405960 - (LA) OPHTHALMIC OUTPATIENT SURGERY CENTER PARTNERS LLCLAAmbulatory Surgical Clinic/Center (261QA1903X)
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist

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HCPCS C5278 vs. Other Skin Substitute Graft Application Codes

The HCPCS C5278 code is part of the Outpatient PPS services used for Skin Substitute Graft Application. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The HCPCS C5278 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
C5277-HCPCSModerateApplication of low cost skin substitute graft to face, scalp, eyelids, mouth, neck, ears, orbits, genitalia, hands, feet, and/or multiple digits, total wound surface area greater than or equal to 100 sq cm; first 100 sq cm wound surface area, or 1% of body area of infants and children
C5278-HCPCSLowApplication of low cost skin substitute graft to face, scalp, eyelids, mouth, neck, ears, orbits, genitalia, hands, feet, and/or multiple digits, total wound surface area greater than or equal to 100 sq cm; each additional 100 sq cm wound surface area, or part thereof, or each additional 1% of body area of infants and children, or part thereof (list separately in addition to code for primary procedure)
C7500-HCPCSLowDebridement, bone including epidermis, dermis, subcutaneous tissue, muscle and/or fascia, if performed, first 20 sq cm or less with manual preparation and insertion of deep (eg, subfacial) drug-delivery device(s)

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including HCPCS C5278. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the C5278 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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