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HCPCS C5278 Fee Schedule

Last Verified: December 2025

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Application of low cost skin substitute graft to face, scalp, eyelids, mouth, neck, ears, orbits, genitalia, hands, feet, and/or multiple digits, total wound surface area greater than or equal to 100 sq cm; each additional 100 sq cm wound surface area, or part thereof, or each additional 1% of body area of infants and children, or part thereof (list separately in addition to code for primary procedure)
Key FactDetail
Service Type

Outpatient PPS

Skin Substitute Graft Application

Complexity LevelLow

National average reimbursement for HCPCS C5278 by major payers:

bcbs

$22.94

uhc

$54.00

aetna

$49.42

cigna

$N/A

Preview provider-level rates for...
For billing codeHCPCS C5278
PayerCodeRateNPITax IDStateSpecialty

Select a payer to view fee schedule data

Choose a payer from the options above to see rates for HCPCS C5278

United
C5278$723.001649488511 - TOURO INFIRMARY ANESTHESIA SERVICES720423659 - (LA) TOURO INFIRMARYLAGeneral Acute Care Hospital (282N00000X)
United
C5278$96.001598804486 - SHREVEPORT SURGERY CENTER PTRSHP721126552 - (LA) SHREVEPORT SURGERY CENTER OF CADDO PARISH, INC.LAAmbulatory Surgical Clinic/Center (261QA1903X)
United
C5278$495.001588631311 - SURGICAL SPECIALTY CENTER OF BATON ROUGE, LLC, SURGICAL SPECIALTY CENTER OF BATON ROUGE263120962 - (LA) SURGICAL SPECIALTY CENTER OF BATON ROUGE, LLCLAGeneral Acute Care Hospital (282N00000X)
United
C5278$688.001104181247 - ADVANCED SURGERY CENTER OF NORTHERN LOUISIANA LLC455502071 - (LA) ADVANCED SURGERY CENTER OF NORTHERN LOUISIANA, LLCLAAmbulatory Surgical Clinic/Center (261QA1903X)
United
C5278$2819.001720133234 - OCHSNER BAYOU, LLC, OCHSNER ST ANNE GENERAL HOSPITAL204670876 - (LA) OCHSNER BAYOU, LLCLACritical Access Hospital (282NC0060X)
United
C5278$434.001114929957 - OPHTHALMIC OUTPATIENT SURGERY CENTER PARTNERS, LLC, OUTPATIENT SURGERY CENTER FOR SIGHT721405960 - (LA) OPHTHALMIC OUTPATIENT SURGERY CENTER PARTNERS LLCLAAmbulatory Surgical Clinic/Center (261QA1903X)
United
C5278$1033.001427536325 - UNIVERSITY HEALTH SHREVEPORT LLC, OCHSNER LSU HEALTH SHREVEPORT831173631LAGeneral Acute Care Hospital (282N00000X)
United
C5278$1154.001518924109 - TERREBONNE PARISH HOSPITAL SERVICE DISTRICT #1, TERREBONNE GENERAL MEDICAL CENTER720880258 - (LA) TERREBONNE HOSPITAL SERVICE DISTRICT NO 1LAGeneral Acute Care Hospital (282N00000X)
United
C5278$478.001265437644 - WEST JEFFERSON HOLDINGS, LLC, WEST JEFFERSON MEDICAL CENTER472667968 - WEST JEFFERSON HOLDINGS, LLCLAGeneral Acute Care Hospital (282N00000X)
United
C5278$1859.001255401519 - THE MEDICAL CENTER INC, PIEDMONT COLUMBUS REGIONAL MIDTOWN581685139 - (GA) THE MEDICAL CENTER INCGAGeneral Acute Care Hospital (282N00000X)
United
C5278$1473.001992799050 - GRADY MEMORIAL HOSPITAL CORPORATION, GRADY HEALTH SYSTEMS262037695 - GRADY MEMORIAL HOSPITAL CORPORATIONGAGeneral Acute Care Hospital (282N00000X)
United
C5278$2288.001528056066 - HAMILTON MEDICAL CENTER, INC.581519911 - HAMILTON MEDICAL CENTER INCGAGeneral Acute Care Hospital (282N00000X)
United
C5278$1741.001588665566 - UNIVERSITY HEALTH SERVICES,INC, UNIVERSITY HOSPITAL581581103 - UNIVERSITY HEALTH SERVICES INCGAGeneral Acute Care Hospital (282N00000X)
United
C5278$5479.001841701562 - NAVICENT HEALTH BALDWIN, INC, NAVICENT HEALTH BALDWIN823914925 - (GA) NAVICENT HEALTH BALDWINGAGeneral Acute Care Hospital (282N00000X)
United
C5278$1265.001316158793 - ST. JOSEPH'S HOSPITAL580566257 - (GA) SAINT JOSEPHS HOSPITAL OF ATLANTA INCGACritical Access Hospital (282NC0060X)
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist

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HCPCS C5278 vs. Other Skin Substitute Graft Application Codes

The HCPCS C5278 code is part of the Outpatient PPS services used for Skin Substitute Graft Application. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The HCPCS C5278 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
C5277-HCPCSModerateApplication of low cost skin substitute graft to face, scalp, eyelids, mouth, neck, ears, orbits, genitalia, hands, feet, and/or multiple digits, total wound surface area greater than or equal to 100 sq cm; first 100 sq cm wound surface area, or 1% of body area of infants and children
C5278-HCPCSLowApplication of low cost skin substitute graft to face, scalp, eyelids, mouth, neck, ears, orbits, genitalia, hands, feet, and/or multiple digits, total wound surface area greater than or equal to 100 sq cm; each additional 100 sq cm wound surface area, or part thereof, or each additional 1% of body area of infants and children, or part thereof (list separately in addition to code for primary procedure)
C7500-HCPCSLowDebridement, bone including epidermis, dermis, subcutaneous tissue, muscle and/or fascia, if performed, first 20 sq cm or less with manual preparation and insertion of deep (eg, subfacial) drug-delivery device(s)

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including HCPCS C5278. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the C5278 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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