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HCPCS J1458 (Naglazyme) Fee Schedule

Last Verified: January 2026

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Injection, galsulfase, 1 mg
Key FactDetail
Service Type

Drugs Administered Other than Oral Method

Drugs, Administered by Injection

Common Place of Service

None

99 - Other POS

Complexity LevelModerate
Medicare Payment Limit
$508.758BuyandBill.com
WAC Price
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Related NDC Codes

68135-0020-01 - NAGLAZYME (PF) 1 MG/ML


National average reimbursement for HCPCS J1458 by major payers:

bcbs

$501.22

uhc

$495.77

aetna

$514.22

cigna

$513.26

Preview provider-level rates for...
For billing codeHCPCS J1458
PayerCodeRateNPITax IDStateSpecialty

Select a payer to view fee schedule data

Choose a payer from the options above to see rates for HCPCS J1458

United
J1458$484.751487607784 - NORTHWEST HOSPITAL LLC, NORTHWEST MEDICAL CENTER621762430AZGeneral Acute Care Hospital (282N00000X)
United
J1458$484.921720159338 - MEMORIAL HOSPITAL OF UNION COUNTY, MEMORIAL HOSPITAL316402480 - (OH) MEMORIAL HOSPITAL OF UNION COUNTYOHGeneral Acute Care Hospital (282N00000X)
United
J1458$484.751346248986 - JOHNSON MEMORIAL HOSPITAL, JOHNSON MEMORIAL HOSPITAL351166081 - JOHNSON MEMORIAL HOSPITALINGeneral Acute Care Hospital (282N00000X)
United
J1458$484.921659411486 - GRAYS HARBOR HOUSE HOSPITALIST910568304 - (WA) GRAYS HARBOR COMMUNITY HOSPITALWAGeneral Acute Care Hospital (282N00000X)
United
J1458$631.141407854771 - THE TOLEDO HOSPITAL344428256 - (OH) TOLEDO HOSPITALOHGeneral Acute Care Hospital (282N00000X)
United
J1458$484.441417465824 - ATHENS HOSPITAL, LLC823934511TXGeneral Acute Care Hospital (282N00000X)
United
J1458$570.971538112230 - ASPIRUS STEVENS POINT HOSPITAL & CLINICS, INC., ASPIRUS STEVENS POINT HOSPITAL & CLINICS, INC.390808443 - ASPIRUS STEVENS POINT HOSPITAL & CLINICS INCWIGeneral Acute Care Hospital (282N00000X)
United
J1458$663.951902923170 - ASPIRUS WAUSAU HOSPITAL, INC, ASPIRUS WAUSAU HOSPITAL THERAPIES391138241 - ASPIRUS WAUSAU HOSPITAL INCWIGeneral Acute Care Hospital (282N00000X)
United
J1458$484.921346241973 - CORNING HOSPITAL160393490 - (NY) CORNING HOSPITALNYGeneral Acute Care Hospital (282N00000X)
United
J1458$484.751144632035 - ST CATHERINE HOSPITAL, ST CATHERINE PODIATRY611726975KSGeneral Acute Care Hospital (282N00000X)
United
J1458$922.321295971950 - UCSF MEDICAL CENTER943281660CAGeneral Acute Care Hospital (282N00000X)
United
J1458$484.921194790055 - MARTIN MEMORIAL MEDICAL CENTER INC, MARTIN MEDICAL CENTER590637874 - MARTIN MEMORIAL MEDICAL CENTER INCFLGeneral Acute Care Hospital (282N00000X)
United
J1458$436.271811912405 - NASSAU HEALTH CARE CORPORATION, NUMC DEPARTMENT OF NEUROLOGY, FPP113465690NYGeneral Acute Care Hospital (282N00000X)
United
J1458$1165.391013918747 - CLEVELAND COUNTY HEALTHCARE SYSTEM, CLEVELAND REGIONAL MEDICAL CENTER560529945NCGeneral Acute Care Hospital (282N00000X)
United
J1458$484.921255334173 - FROEDTERT MEMORIAL LUTHERAN HOSPITAL, INC., FROEDTERT HOSPITAL390987025 - (WI) COMMUNITY MEMORIAL HOSPITAL OF MENOMONEE FALLS INCWIGeneral Acute Care Hospital (282N00000X)
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist

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HCPCS J1458 vs. Other Drugs, Administered by Injection Codes

The HCPCS J1458 code is part of the Drugs Administered Other than Oral Method services used for Drugs, Administered by Injection. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The HCPCS J1458 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
68135-0020-01-NDCModerateNAGLAZYME (PF) 1 MG/ML
J1457-HCPCSLowInjection, gallium nitrate, 1 mg
J1458-HCPCSModerateInjection, galsulfase, 1 mg
J1459-HCPCSLowInjection, immune globulin (Privigen), intravenous, non-lyophilized (e.g., liquid), 500 mg

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including HCPCS J1458. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the J1458 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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