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HCPCS J1559 (Hizentra) Fee Schedule

Last Verified: January 2026

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Injection, immune globulin (Hizentra), 100 mg
Key FactDetail
Service Type

Drugs Administered Other than Oral Method

Drugs, Administered by Injection

Common Place of Service

None

99 - Other POS

Complexity LevelLow
Medicare Payment Limit
$14.337BuyandBill.com
WAC Price
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Related NDC Codes

44206-0451-01 - HIZENTRA (SINGLE-USE VIAL,PF) 20%

44206-0452-02 - HIZENTRA (SINGLE-USE VIAL,PF) 20%

44206-0454-04 - HIZENTRA (SINGLE-USE VIAL,PF) 20%

44206-0455-10 - HIZENTRA (SINGLE-USE VIAL,PF) 20%

44206-0455-25 - HIZENTRA (SINGLE-USE,PF) 20%


National average reimbursement for HCPCS J1559 by major payers:

bcbs

$14.79

uhc

$14.50

aetna

$14.82

cigna

$14.18

Preview provider-level rates for...
For billing codeHCPCS J1559
PayerCodeRateNPITax IDStateSpecialty

Select a payer to view fee schedule data

Choose a payer from the options above to see rates for HCPCS J1559

United
J1559$18.971114014297 - JODI SELZER815309615NYHematology & Oncology Physician (207RH0003X)
United
J1559$19.271356441513 - SALLY HODDER550492006 - WEST VIRGINIA UNIVERSITY MEDICAL CORPORATIONNJInfectious Disease Physician (207RI0200X)
United
J1559$14.771528239159 - JOSE SERPA-ALVAREZ752931720TXInfectious Disease Physician (207RI0200X)
United
J1559$13.641104060904 - URIEL SANDKOVSKY751892059 - (TX) RESOURCE CENTER OF DALLAS INCTXInfectious Disease Physician (207RI0200X)
United
J1559$22.511063507663 - SOO HEE KIM-DELIO742800601 - (TX) DELL CHILDRENS MEDICAL GROUPTXAllergy & Immunology Physician (207K00000X)
United
J1559$20.111124027487 - RAYMOND PASTORE131623978NYHematology & Oncology Physician (207RH0003X)
United
J1559$12.271003082660 - SUKRUT DWIVEDI223089117 - (NJ) ID CARE LLCNJInfectious Disease Physician (207RI0200X)
United
J1559$14.941871948059 - SYLWIA NOWAK363142979 - (IL) ALLERGY ASTHMA MEDICAL ASSOCIATES LTDILAllergy & Immunology Physician (207K00000X)
United
J1559$24.451861440661 - GUILLERMO RODRIGUEZ822026363 - WASHINGTON UNIVERSITY PHYSICIANS IN ILLINOIS INCILMedical Oncology Physician (207RX0202X)
United
J1559$13.641023084928 - RONALD NAHASS223089117 - (NJ) ID CARE LLCNJInfectious Disease Physician (207RI0200X)
United
J1559$13.641134372659 - HASHMI RAFEEK223089117 - (NJ) ID CARE LLCNJInfectious Disease Physician (207RI0200X)
United
J1559$21.811518132489 - GIBRAN MAHMUD371160364 - (IL) CANCER CARE SPECIALISTS OF CENTRAL ILLINOIS SCILHematology & Oncology Physician (207RH0003X)
United
J1559$15.271689937740 - SUKHDEEP KAUR264203938 - (NJ) PRINCETON HEALTHCARE AFFILIATED PHYSICIANS PCNJMedical Oncology Physician (207RX0202X)
United
J1559$13.641669460366 - ROGERIO LILENBAUM953901271 - (FL) COMPREHENSIVE CANCER CENTERS INCCTMedical Oncology Physician (207RX0202X)
United
J1559$12.271871556316 - PRASHANT MALHOTRA113391292 - (NY) SOUTH SHORE INFECTIOUS DISEASES PCNYInfectious Disease Physician (207RI0200X)
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist

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HCPCS J1559 vs. Other Drugs, Administered by Injection Codes

The HCPCS J1559 code is part of the Drugs Administered Other than Oral Method services used for Drugs, Administered by Injection. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The HCPCS J1559 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
44206-0451-01-NDCModerateHIZENTRA (SINGLE-USE VIAL,PF) 20%
J1558-HCPCSLowInjection, immune globulin (xembify), 100 mg
J1559-HCPCSLowInjection, immune globulin (Hizentra), 100 mg
J1560-HCPCSModerateInjection, gamma globulin, intramuscular, over 10 cc

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including HCPCS J1559. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the J1559 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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