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HCPCS J2251 (Midazolam Hcl) Fee Schedule

Last Verified: December 2025

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Injection, midazolam hydrochloride (wg critical care) not therapeutically equivalent to j2250, per 1 mg
Key FactDetail
Service Type

Drugs Administered Other than Oral Method

Drugs, Administered by Injection

Common Place of Service

None

11 - Office

24 - Ambulatory Surgical Center

41 - Ambulance - Land

Complexity LevelLow
Medicare Payment Limit
$0.204BuyandBill.com
WAC Price
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Related NDC Codes

25021-0688-82 - MIDAZOLAM-SODIUM CHLORIDE 10X50ML 50 MG/50 ML-0.9%

25021-0688-87 - MIDAZOLAM-SODIUM CHLORIDE SD 100 MG/100 ML-0.9%

44567-0610-10 - MIDAZOLAM-SODIUM CHLORIDE (10X50ML,PF) 50 MG/50 ML-0.9%

44567-0611-10 - MIDAZOLAM-SODIUM CHLORIDE (10X100ML,PF) 100 MG/100 ML-0.9%

65219-0650-10 - MIDAZOLAM-SODIUM CHLORIDE SD 100 MG/100 ML-0.9%


National average reimbursement for HCPCS J2251 by major payers:

bcbs

$0.21

uhc

$0.19

aetna

$0.24

cigna

$0.20

Preview provider-level rates for...
For billing codeHCPCS J2251
PayerCodeRateNPITax IDStateSpecialty

Select a payer to view fee schedule data

Choose a payer from the options above to see rates for HCPCS J2251

United
J2251$0.181457619017 - DIMITRY HIKIN462916938 - (NY) MONTEFIORE MOUNT VERNON HOSPITALNYGeneral Acute Care Hospital (282N00000X)
United
J2251$0.171225038953 - PARKVIEW COMMUNITY HOSPITAL MEDICAL CENTER351972384 - PARKVIEW HEALTH SYSTEM INCCAGeneral Acute Care Hospital (282N00000X)
United
J2251$0.251093049900 - CLEVELAND CLINIC341932969OHGeneral Acute Care Hospital (282N00000X)
United
J2251$0.181346285657 - UNIVERSITY OF ROCHESTER, STRONG MEMORIAL HOSPITAL160743209 - UNIVERSITY OF ROCHESTERNYGeneral Acute Care Hospital (282N00000X)
United
J2251$0.151831115641 - OZARKS MEDICAL CENTER, OZARKS HEALTHCARE446005758 - OZARKS MEDICAL CENTERMOGeneral Acute Care Hospital (282N00000X)
United
J2251$0.181134734528 - ROBERT PACKER HOSPITAL, ROBERT PACKER HOSPITAL, TOWANDA CAMPUS240795463 - (PA) ROBERT PACKER HOSPITALPAGeneral Acute Care Hospital (282N00000X)
United
J2251$0.181831633080 - GLENDORA RADIOLOGICAL ASSOCIATES, INC952649911 - (CA) GLENDORA RADIOLOGICAL ASSOCIATES, INC. A MEDICAL GROUPCAGeneral Acute Care Hospital (282N00000X)
United
J2251$0.181346611829 - AMARI THOMAS300520570 - (TX) METHODIST HOSPITALTXGeneral Acute Care Hospital (282N00000X)
United
J2251$0.171942317656 - MEMORIAL HOSPITAL356001853 - (IN) MEMORIAL HOSPITALINGeneral Acute Care Hospital (282N00000X)
United
J2251$0.271336106806 - FALMOUTH HOSPITAL ASSOCIATION INC42220716 - (MA) CAPE COD HEALTHCARE INCMAGeneral Acute Care Hospital (282N00000X)
United
J2251$0.171649573023 - WAYNE MEMORIAL HOSPITAL240798839 - (PA) WAYNE MEMORIAL HOSPITALPAGeneral Acute Care Hospital (282N00000X)
United
J2251$0.201619209574 - VALLEY MEDICAL GROUP-RENTON, PUBLIC HOSPITAL DISTRICT #1 OF KING COUNTY916000986 - (WA) PUBLIC HOSPITAL DISTRICT 1 OF KING COUNTYWAGeneral Acute Care Hospital (282N00000X)
United
J2251$0.181700158060 - ARMEN ARSHAKYAN954487496CAGeneral Acute Care Hospital (282N00000X)
United
J2251$0.181669692752 - NEWPORT HOSPITAL, NEWPORT HOSPITAL VASCULAR LAB50258914 - (RI) NEWPORT HOSPITALRIGeneral Acute Care Hospital (282N00000X)
United
J2251$0.181194776351 - THE FREDERICK FERRIS THOMPSON HOSPITAL, THOMSPON HEALTH160743024 - (NY) THE FREDERICK FERRIS THOMPSON HOSPI TALNYGeneral Acute Care Hospital (282N00000X)
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist

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HCPCS J2251 vs. Other Drugs, Administered by Injection Codes

The HCPCS J2251 code is part of the Drugs Administered Other than Oral Method services used for Drugs, Administered by Injection. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The HCPCS J2251 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
25021-0688-82-NDCModerateMIDAZOLAM-SODIUM CHLORIDE 10X50ML 50 MG/50 ML-0.9%
J2250-HCPCSLowInjection, midazolam hydrochloride, per 1 mg
J2251-HCPCSLowInjection, midazolam hydrochloride (wg critical care) not therapeutically equivalent to j2250, per 1 mg
J2260-HCPCSLowInjection, milrinone lactate, 5 mg

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including HCPCS J2251. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the J2251 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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