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HCPCS J3397 (Mepsevii) Fee Schedule

Last Verified: December 2025

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Injection, vestronidase alfa-vjbk, 1 mg
Key FactDetail
Service Type

Drugs Administered Other than Oral Method

Drugs, Administered by Injection

Common Place of Service

None

99 - Other POS

Complexity LevelModerate
WAC Price
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Related NDC Codes

69794-0001-01 - MEPSEVII (PF) 2 MG/1 ML


National average reimbursement for HCPCS J3397 by major payers:

bcbs

$250.79

uhc

$277.33

aetna

$274.41

cigna

$279.17

Preview provider-level rates for...
For billing codeHCPCS J3397
PayerCodeRateNPITax IDStateSpecialty

Select a payer to view fee schedule data

Choose a payer from the options above to see rates for HCPCS J3397

United
J3397$287.911588068431 - SHELLA FRENEL273459101 - (NY) GENESIS MEDICAL HEALTH PCNYGeneral Acute Care Hospital (282N00000X)
United
J3397$423.701427098169 - MERCY HOSPITALS EAST COMMUNITIES, MERCY HOSPITAL ST LOUIS430653493 - MERCY HOSPITALS EAST COMMUNITIESMOGeneral Acute Care Hospital (282N00000X)
United
J3397$665.441326442336 - THE CHARLOTTE-MECKLENBURG HOSPITAL AUTHORITY, ATRIUM HEALTH CLEVELAND560529945NCGeneral Acute Care Hospital (282N00000X)
United
J3397$271.601104904143 - EYE & EAR CLINIC OF CHARLESTON INC, CHARLESTON SURGICAL HOSPITAL550526191 - (WV) THE EYE & EAR CLINIC OF CHARLESTON, INC.WVGeneral Acute Care Hospital (282N00000X)
United
J3397$271.601881018224 - HOMAIRA OMAR453303364 - (NY) ADVANCED LUNG CARE PLLCNYGeneral Acute Care Hospital (282N00000X)
United
J3397$271.601992703540 - DUKE UNIVERSITY HEALTH SYSTEM, INC., DUKE UNIVERSITY HOSPITAL562070036 - DUKE UNIVERSITY HEALTH SYSTEM INCNCGeneral Acute Care Hospital (282N00000X)
United
J3397$271.601770982480 - MONUMENT HEALTH RAPID CITY HOSPITAL, INC., MONUMENT HEALTH NEUROLOGY AND REHABILITATION460320177 - (SD) RAPID CITY EMERGENCY SERVICESSDGeneral Acute Care Hospital (282N00000X)
United
J3397$258.831609311000 - MOBILE INFIRMARY ASSOCIATION, THE INFIRMARY CENTER FOR WOUND HEALING630288856 - (AL) MOBILE INFIRMARY ASSOCIATIONALGeneral Acute Care Hospital (282N00000X)
United
J3397$385.691730327396 - NORTH HAWAII COMMUNITY HOSPITAL, INC., HOSPITALIST PHYSICIAN GROUP990260423 - (HI) QUEENS NORTH HAWAII COMMUNITY HOSPITALHIGeneral Acute Care Hospital (282N00000X)
United
J3397$287.911669883401 - RABI UPADHYAY132655001 - NEW YORK CITY HEALTH AND HOSPITALS CORPORATIONNYGeneral Acute Care Hospital (282N00000X)
United
J3397$271.601184910747 - LAKE HOSPITAL SYSTEM, INC.341425870 - (OH) UNIVERSITY HOSPITALS HEALTH SYSTEM INCOHGeneral Acute Care Hospital (282N00000X)
United
J3397$271.601720098791 - IRWIN COUNTY HOSPITAL586003765GAGeneral Acute Care Hospital (282N00000X)
United
J3397$271.601972503464 - KING'S DAUGHTERS MEDICAL CENTER610444716 - ASHLAND HOSPITAL CORPORATIONMSGeneral Acute Care Hospital (282N00000X)
United
J3397$271.601427055821 - NORTHEAST GEORGIA MEDICAL CENTER, INC.581177261 - (GA) GAINESVILLE RADIOLOGY GROUPGAGeneral Acute Care Hospital (282N00000X)
United
J3397$271.601467007112 - READING HOSPITAL, READING HOSPITAL TRANSPLANT CENTER231352204 - (PA) READING HOSPITALPAGeneral Acute Care Hospital (282N00000X)
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist

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HCPCS J3397 vs. Other Drugs, Administered by Injection Codes

The HCPCS J3397 code is part of the Drugs Administered Other than Oral Method services used for Drugs, Administered by Injection. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The HCPCS J3397 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
69794-0001-01-NDCModerateMEPSEVII (PF) 2 MG/1 ML
J3396-HCPCSLowInjection, verteporfin, 0.1 mg
J3397-HCPCSModerateInjection, vestronidase alfa-vjbk, 1 mg
J3398-HCPCSHighInjection, voretigene neparvovec-rzyl, 1 billion vector genomes

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including HCPCS J3397. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the J3397 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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