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MS-DRG 421 Fee Schedule

Last Verified: October 2026

Healthcare providers use this code to document and receive reimbursement for visits that address high-level medical decision-making, often including multiple diagnoses or prescription management.

HEPATOBILIARY DIAGNOSTIC PROCEDURES WITH CC
Key FactDetail
Service Type

Diseases & Disorders of the Hepatobiliary System & Pancreas

Common Place of Service

21 - Inpatient Hospital

22 - On Campus Outpatient Hospital

Complexity LevelHigh

National average reimbursement for MS-DRG 421 by major payers:

bcbs

$22,524.81

uhc

$22,369.98

aetna

$25,911.42

cigna

$26,752.71

Compare published rates across providers.

Choose a payer to see a sample of rates for MS-DRG 421.

MS-DRG 421
5 of 25 sample ratesHigher to lower in this preview
  1. Desert Regional Medical Center, Inc., Desert Regional Medical Center

    CAGeneral Acute Care HospitalNPI 1104856095Tax ID 75-2694137

    $49,113.26Published rate
  2. Bbh Pbmc, LLC, Princeton Baptist Medical Center

    ALPsychiatric Hospital UnitNPI 1659725901Tax ID 47-4775351

    $28,366.50Published rate
  3. Public Health Trust Of Miami Dade County Florida, Jackson North Medical Center Rehab

    Public Health Trust Of Miami-Dade County Florida

    FLRehabilitation Hospital UnitNPI 1912932336Tax ID 59-1713947

    $25,133.88Published rate
  4. Summit Surgical LLC

    KSSpecial HospitalNPI 1932117975Tax ID 20-3283620

    $13,433.23Published rate
  5. Madison County Hospital Health Systems, Inc., Madison County Memorial Hospital

    Madison County Hospital Health Systems Inc

    FLCritical Access HospitalNPI 1104821461Tax ID 59-2319288

    $9,555.40Published rate

National sample. Rates vary by location, specialty, and contract.

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MS-DRG 421 vs. Other Diseases & Disorders of the Hepatobiliary System & Pancreas Codes

The MS-DRG 421 code is part of the Diseases & Disorders of the Hepatobiliary System & Pancreas services . It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The MS-DRG 421 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
420-APR-DRGHighDIABETES
420-MS-DRGHighHEPATOBILIARY DIAGNOSTIC PROCEDURES WITH MCC
421-MS-DRGHighHEPATOBILIARY DIAGNOSTIC PROCEDURES WITH CC
422-APR-DRGHighHYPOVOLEMIA & RELATED ELECTROLYTE DISORDERS

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including MS-DRG 421. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 421 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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