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MS-DRG 421 Fee Schedule

Last Verified: March 2026

Healthcare providers use this code to document and receive reimbursement for visits that address high-level medical decision-making, often including multiple diagnoses or prescription management.

Hepatobiliary Diagnostic Procedures with CC
Key FactDetail
Service Type

Diseases & Disorders of the Hepatobiliary System & Pancreas

Common Place of Service

21 - Inpatient Hospital

22 - On Campus Outpatient Hospital

Complexity LevelHigh

National average reimbursement for MS-DRG 421 by major payers:

bcbs

$22,524.81

uhc

$22,369.98

aetna

$25,911.42

cigna

$26,752.71

Preview provider-level rates for...
For billing codeMS-DRG 421
PayerCodeRateNPITax IDStateSpecialty

Select a payer to view fee schedule data

Choose a payer from the options above to see rates for MS-DRG 421

United
421$25299.271255785390 - PROSPECT CCMC, LLC811507712PAPsychiatric Hospital Unit (273R00000X)
United
421$26642.101639458946 - HURON VALLEY SINAI HOSPITAL272844563MIGeneral Acute Care Hospital (282N00000X)
United
421$26574.971750484721 - LOYOLA UNIVERSITY MEDICAL CENTER, FOSTER G. MCGAW HOSPITAL364015560 - LOYOLA UNIVERSITY MEDICAL CENTERILRehabilitation Hospital Unit (273Y00000X)
United
421$9989.191255369245 - SAINT CATHERINE HOSPITAL OF INDIANA, LLC, D/B/A SAINT CATHERINE REGIONAL HOSPITAL204134578 - (IN) SAINT CATHERINE HOSPITAL OF INDIANA, LLCINGeneral Acute Care Hospital (282N00000X)
United
421$11824.801952028904 - STATESVILLE HMA LLC562206788 - STATESVILLE HMA LLCNCPsychiatric Hospital (283Q00000X)
United
421$9555.401104821461 - MADISON COUNTY HOSPITAL HEALTH SYSTEMS, INC., MADISON COUNTY MEMORIAL HOSPITAL592319288 - (FL) MADISON COUNTY HOSPITAL HEALTH SYSTEMS INCFLCritical Access Hospital (282NC0060X)
United
421$29159.101659456994 - CARONDELET HEALTH NETWORK, ST MARY'S HOSPITAL474131755AZRehabilitation Hospital Unit (273Y00000X)
United
421$18344.251386697688 - ORO VALLEY HOSPITAL LLC, ORO VALLEY HOSPITAL522379881AZGeneral Acute Care Hospital (282N00000X)
United
421$49113.261104856095 - DESERT REGIONAL MEDICAL CENTER, INC., DESERT REGIONAL MEDICAL CENTER752694137CAGeneral Acute Care Hospital (282N00000X)
United
421$32666.841508956509 - THE UNIVERSITY OF CHICAGO MEDICAL CENTER363488183 - UNIVERSITY OF CHICAGO MEDICAL CENTERILGeneral Acute Care Hospital (282N00000X)
United
421$12516.171649794421 - POTTSTOWN HOSPITAL, LLC, POTTSTOWN HOSPITAL822132538PAGeneral Acute Care Hospital (282N00000X)
United
421$25905.881689737223 - SWAIN COUNTY HOSPITAL, INC.320441929NCCritical Access Hospital (282NC0060X)
United
421$30773.771932584802 - HOLY CROSS HOSPITAL590791028 - HOLY CROSS HOSPITAL INCFLRehabilitation Hospital (283X00000X)
United
421$20407.781225116486 - SINGING RIVER HEALTH SYSTEM, SINGING RIVER HOSPITAL COMPREHENSIVE REHABILITATION CENTER646000515 - SINGING RIVER HEALTH SYSTEMMSRehabilitation Hospital Unit (273Y00000X)
United
421$13393.161710396932 - OSF HEALTHCARE SYSTEM, OSF SAINT ANTHONY'S HEALTH CENTER370813229 - (IL) OSF HEALTHCARE SYSTEMILGeneral Acute Care Hospital (282N00000X)
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist

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MS-DRG 421 vs. Other Diseases & Disorders of the Hepatobiliary System & Pancreas Codes

The MS-DRG 421 code is part of the Diseases & Disorders of the Hepatobiliary System & Pancreas services . It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The MS-DRG 421 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
420-APR-DRGHighDIABETES
420-MS-DRGHighHepatobiliary Diagnostic Procedures with MCC
421-MS-DRGHighHepatobiliary Diagnostic Procedures with CC
422-APR-DRGHighHYPOVOLEMIA & RELATED ELECTROLYTE DISORDERS

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including MS-DRG 421. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 421 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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