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CPT 45331 Fee Schedule

Last Verified: November 2025

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Sigmoidoscopy; Biopsy Collect Speciment
Key FactDetail
Service Type

Surgery

Surgical Procedures on the Digestive System

Common Place of Service

24 - Ambulatory Surgical Center

22 - On Campus Outpatient Hospital

Common Modifiers

None

59 - Distinct Procedural Service

51 - Multiple procedures

Complexity LevelModerate
CMS$272.03 Physician Fee Schedule

National average reimbursement for CPT 45331 by major payers:

bcbs

$284.05

uhc

$308.23

aetna

$359.42

cigna

$428.89

Preview provider-level rates for...
For billing codeCPT 45331
PayerCodeRateNPITax IDStateSpecialty

Select a payer to view fee schedule data

Choose a payer from the options above to see rates for CPT 45331

United
45331$416.001497011308 - BENJAMIN CHUNG MD INC, RIVERWALK SURGERY CENTER454738248 - (CA) BENJAMIN CHUNG MD INCCAAmbulatory Surgical Clinic/Center (261QA1903X)
United
45331$454.001346386604 - DIGESTIVE HEALTH CENTER LLC341955920 - DIGESTIVE HEALTH CENTER, LTD.OHAmbulatory Surgical Clinic/Center (261QA1903X)
United
45331$580.001629041157 - THE WESTLAKE OPHTHALMOLOGY ASC, LLC, WESTLAKE EYE SURGERY CENTER621748633 - (CA) THE WESTLAKE OPHTHALMOLOGY ASC LLCCAAmbulatory Surgical Clinic/Center (261QA1903X)
United
45331$485.001063459451 - CARROLL COUNTY AMBULATORY SURGICAL CENTER522165022 - (MD) CARROLL COUNTY AMBULATORY SURGICAL CENTERMDAmbulatory Surgical Clinic/Center (261QA1903X)
United
45331$2413.001225064876 - ROCK HILL SURGERY CENTER, LLC, CAROLINA SURGICAL CENTER752562111 - (SC) ROCK HILL SURGERY CENTER LLCSCAmbulatory Surgical Clinic/Center (261QA1903X)
United
45331$920.001912090432 - MEDSTAR SURGERY CENTER AT LAFAYETTE CENTRE, LLC812557673 - (DC) MEDSTAR SURGERY CENTER AT LAFAYETTE CENTRE LLCDCAmbulatory Surgical Clinic/Center (261QA1903X)
United
45331$1379.001144291261 - OCEAN SURGICAL PAVILION, PC, OCEAN SURGICAL PAVILION223182653NJAmbulatory Surgical Clinic/Center (261QA1903X)
United
45331$631.001003374711 - RIVERVIEW SURGICAL CENTER LLC821368525 - (NE) RIVERVIEW SURGICAL CENTER, LLCNEAmbulatory Surgical Clinic/Center (261QA1903X)
United
45331$254.001477562148 - SANI EYE CENTER, INC., SANI EYE SURGERY CENTER953764955 - (CA) SANI EYE CENTER INCCAAmbulatory Surgical Clinic/Center (261QA1903X)
United
45331$400.001457545980 - SAND LAKE SURGERY CENTER, LP, SAND LAKE SURGERY CENTER273787593 - (FL) SAND LAKE SURGICENTER, LLCFLAmbulatory Surgical Clinic/Center (261QA1903X)
United
45331$344.001831881135 - VERTRAE SURGERY CENTER, LLC883920617OHAmbulatory Surgical Clinic/Center (261QA1903X)
United
45331$367.001538432844 - BARNET DULANEY PERKINS EYE CENTER, PC, AMERICAN VISION PARTNERS562589722 - BARNET DULANEY PERKINS EYE CENTER PLLCAZAmbulatory Surgical Clinic/Center (261QA1903X)
United
45331$600.001316082365 - WEST WILSHIRE MEDICAL SURGICAL CENTER INC.954421811 - (CA) WEST WILSHIRE MEDICAL SURGICAL CCAAmbulatory Surgical Clinic/Center (261QA1903X)
United
45331$416.001093156937 - QUALITY CARE SURGERY CENTER, LLC462355538 - (CA) QUALITY CARE SURGERY CENTER LLCCAAmbulatory Surgical Clinic/Center (261QA1903X)
United
45331$238.001265455463 - THE ENDOSCOPY CENTER AT BEL AIR470863243 - (MD) THE ENDOSCOPY CENTER AT BEL AIRMDAmbulatory Surgical Clinic/Center (261QA1903X)
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist

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CPT 45331 vs. Other Surgical Procedures on the Digestive System Codes

The CPT 45331 code is part of the Surgery services used for Surgical Procedures on the Digestive System. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The CPT 45331 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
45330-CPTLowSigmoidoscopy Flexible; Diagnostic Including Collection Of Specimen(S) By Brushing Or Washing When Performed (Separate Procedure) (Desc Revised 01/01/15)
45331-CPTModerateSigmoidoscopy; Biopsy Collect Speciment
45338-CPTModerateSigmoidoscopy, Flexible; With Removal Of Tumor(S), Polyp(S), Or Other Lesion(S) By Snare Technique
45341-CPTLowSigmoidoscopy, Flexible; With Endoscopic Ultrasound Examination

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 45331. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 45331 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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