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See a sample rate comparisonCPT 45335 Fee Schedule
Last Verified: September 2026
Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.
Exam Left Colon With Scope, Exam Of The Left Side Of The Lower Colon Using A Flexible Scope Inserted Into The Rectum (Sigmoidoscopy). The Procedure Includes An Injection.
| Key Fact | Detail |
|---|---|
| Service Type | Surgery Surgical Procedures on the Digestive System |
| Common Place of Service | 24 - Ambulatory Surgical Center 22 - On Campus Outpatient Hospital |
| Common Modifiers | None 59 - Distinct Procedural Service 51 - Multiple procedures |
| Complexity Level | Moderate |
| Medicare Fee Schedule | View Medicare rates for 45335 |
| Medicaid Fee Schedule | View Medicaid rates for 45335 |
National average reimbursement for CPT 45335 by major payers:
$297.19
$336.11
$394.16
$134.94
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CPT 45335
5 of 25 sample ratesHigher to lower in this preview
Alegent Creighton Health, Chi Health Ambulatory Surgery Center At Midlands
Alegent Creighton Health
$2,190.06Published rateAdvanced Orthopaedic Surgery Center, LLC, Las Vegas Institute For Advanced Surgery
Advanced Orthopaedic Surgery Center LLC
$700.00Published ratePain & Spine Physicians Surgery Center LLC
Pain Spine Physicians Surgery Center LLC
$450.00Published rateAugusta Plastic Surgery Center, Inc.
Augusta Plastic Surgery Center Inc
$361.00Published rateLakeforest Ambulatory Surgery Center, District Heights Ambulatory Surgery Center
Lakeforest Ambulatory Surgery Center
$184.00Published rate
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See a sample payer proposalCPT 45335 vs. Other Surgical Procedures on the Digestive System Codes
The CPT 45335 code is part of the Surgery services used for Surgical Procedures on the Digestive System. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.
The CPT 45335 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.
| Code | Complexity | Description |
|---|---|---|
| 45321-CPT | Low | Treatment Of Twisted Intestine, An Exam Of The Large Intestine Using A Scope (Sigmoidoscopy). The Procedure Treats A Section That Has Become Twisted. |
| 45335-CPT | Moderate | Exam Left Colon With Scope, Exam Of The Left Side Of The Lower Colon Using A Flexible Scope Inserted Into The Rectum (Sigmoidoscopy). The Procedure Includes An Injection. |
| 45381-CPT | Moderate | Intestinal Exam (Colonoscopy), An Exam Of The Intestine Using A Scope (Colonoscopy). An Injection Is Given Into The Intestinal Tissues During The Exam. |
| 45392-CPT | Moderate | Colonoscopy W Endoscopic Fnb, Colonoscopy Flexible With Transendoscopic Ultrasound Guided Intramural Or Transmural Fine Needle Aspiration Biopsy S Includes Endoscopic Ultrasound Examination Limited To The Rectum Sigmoid Descending Transverse Or Ascending Colon And Cecum And Adjacent Structures |
What is a fee schedule?
A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 45335. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.
Understanding the 45335 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.
Factors that affect fee schedules
Medicare & Medicaid Rates
Government-set reimbursement amounts
Private Insurance Rates
Negotiated rates between providers and insurance companies
Geographic Location
Costs may be higher in urban areas.
Provider Type
Hospital providers may have different rates than private practice.
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