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See a sample rate comparisonCPT 45335 is classified under Surgery, in the Surgical Procedures on the Digestive System subgroup.
| Key Fact | Detail |
|---|---|
| Service Type | Surgery Surgical Procedures on the Digestive System |
| Common Place of Service | 24 - Ambulatory Surgical Center 22 - On Campus Outpatient Hospital |
| Common Modifiers | 59 - Distinct Procedural Service 51 - Multiple procedures |
| Complexity Level | Moderate |
| Medicare Fee Schedule | $328.00 national non-facility rate (2026) · View Medicare rates for 45335 |
| Medicaid Fee Schedule | $255.935 median of the 8 states in the free preview · View Medicaid rates for 45335 |
National average reimbursement for CPT 45335 by major payers:

$297.19
BCBS / Anthem

$336.11
UnitedHealthcare

$394.16
Aetna

$134.94
Cigna
Choose a payer to see a sample of rates for CPT 45335.
Alegent Creighton Health, Chi Health Ambulatory Surgery Center At Midlands
Alegent Creighton Health
Advanced Orthopaedic Surgery Center, LLC, Las Vegas Institute For Advanced Surgery
Advanced Orthopaedic Surgery Center LLC
Pain & Spine Physicians Surgery Center LLC
Pain Spine Physicians Surgery Center LLC
Augusta Plastic Surgery Center, Inc.
Augusta Plastic Surgery Center Inc
Lakeforest Ambulatory Surgery Center, District Heights Ambulatory Surgery Center
Lakeforest Ambulatory Surgery Center
Choose your state and specialty to build a report from payer-published rates.
Rate Benchmarking
Select a published rate, define comparable providers, and see where that rate falls in your market.
See a sample rate comparisonPayer Contract Negotiation
Use your fee schedule and market benchmarks to set target rates and draft a letter for your payer.
See a sample payer proposalCPT 45335 vs. Other Surgical Procedures on the Digestive System Codes
The table lists codes related to 45335. Select one to see its fee schedule.
| Code | Complexity | Description |
|---|---|---|
| 45321-CPT | Low | Treatment Of Twisted Intestine, An Exam Of The Large Intestine Using A Scope (Sigmoidoscopy). The Procedure Treats A Section That Has Become Twisted. |
| 45335-CPT | Moderate | Exam Left Colon With Scope, Exam Of The Left Side Of The Lower Colon Using A Flexible Scope Inserted Into The Rectum (Sigmoidoscopy). The Procedure Includes An Injection. |
| 45381-CPT | Moderate | Intestinal Exam (Colonoscopy), An Exam Of The Intestine Using A Scope (Colonoscopy). An Injection Is Given Into The Intestinal Tissues During The Exam. |
| 45392-CPT | Moderate | Colonoscopy W Endoscopic Fnb, Colonoscopy Flexible With Transendoscopic Ultrasound Guided Intramural Or Transmural Fine Needle Aspiration Biopsy S Includes Endoscopic Ultrasound Examination Limited To The Rectum Sigmoid Descending Transverse Or Ascending Colon And Cecum And Adjacent Structures |
What is a fee schedule?
A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 45335. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.
Understanding the 45335 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.
Factors that affect fee schedules
Medicare & Medicaid Rates
Government-set reimbursement amounts
Private Insurance Rates
Negotiated rates between providers and insurance companies
Geographic Location
Costs may be higher in urban areas.
Provider Type
Hospital providers may have different rates than private practice.
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