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CPT 45388 Fee Schedule

Last Verified: November 2025

Healthcare providers use this code to document and receive reimbursement for visits that address high-level medical decision-making, often including multiple diagnoses or prescription management.

Colonoscopy, Flexible; Diagnostic, Including Collection Of Specimens By Brushing Or Washing, When Performed, With Ablation Of Tumors, Polyss, Or Other Lesionss Includ
Key FactDetail
Service Type

Surgery

Surgical Procedures on the Digestive System

Common Place of Service

24 - Ambulatory Surgical Center

22 - On Campus Outpatient Hospital

Common Modifiers

None

PT - Colorectal cancer screening test; converted to diagnostic test or other procedure

33 - Preventive Services

Complexity LevelHigh
CMS$2,233.53 Physician Fee Schedule

National average reimbursement for CPT 45388 by major payers:

bcbs

$2,357.42

uhc

$2,725.34

aetna

$3,186.72

cigna

$3,692.87

Preview provider-level rates for...
For billing codeCPT 45388
PayerCodeRateNPITax IDStateSpecialty

Select a payer to view fee schedule data

Choose a payer from the options above to see rates for CPT 45388

United
45388$525.001033282173 - TEMECULA VALLEY DAY SURGERY & PAIN THERAPY CENTER, INC.330469645 - (CA) TEMECULA VALLEY DAY SURGERY PAIN THERAPY CENTER INCCAAmbulatory Surgical Clinic/Center (261QA1903X)
United
45388$1938.001326097981 - FREDERICKSBURG AMBULATORY SURGERY CENTER, LLC562322548 - (VA) FREDERICKSBURG AMBULATORY SURGERY CENTER LLCVAAmbulatory Surgical Clinic/Center (261QA1903X)
United
45388$1438.001942230024 - LUTHERVILLE ENDOSCOPY CENTER LLC823193901MDAmbulatory Surgical Clinic/Center (261QA1903X)
United
45388$567.001528024114 - AMBULATORY CARE CENTER PA223479837 - (NJ) AMBULATORY CARE CENTER PANJAmbulatory Surgical Clinic/Center (261QA1903X)
United
45388$801.001689679680 - TOSC, LLC, OSC-HMHP, LLC10724836 - (OH) THE ORTHOPAEDIC SURGERY CENTEROHAmbulatory Surgical Clinic/Center (261QA1903X)
United
45388$1137.001497706626 - CHICAGO PROSTATE CANCER SURGERY CENTER, LLC, DUPAGE MEDICAL GROUP SURGERY CENTER, WESTMONT204403852 - (IL) CHICAGO PROSTATE CANCER SURGERY CENTER LLCILAmbulatory Surgical Clinic/Center (261QA1903X)
United
45388$800.001841672615 - ALLIANCE SURGERY CENTER AT AUGUSTA, LLC474382081 - (GA) ALLIANCE SURGERY CENTER AT AUGUSTA LLCGAAmbulatory Surgical Clinic/Center (261QA1903X)
United
45388$1276.001366559122 - HARVARD PARK SURGERY CENTER, LLC, HARVARD PARK SURGERY CENTER331107194 - (CO) HARVARD PARK SURGERY CENTER LLCCOAmbulatory Surgical Clinic/Center (261QA1903X)
United
45388$1817.001366137440 - SURGERY CENTER OF GEORGETOWN, LLC, GEORGETOWN SURGERY CENTER880604963 - (TX) SURGERY CENTER OF GEORGETOWN LLCTXAmbulatory Surgical Clinic/Center (261QA1903X)
United
45388$400.001942553300 - COLUMBIA SURGICAL INSTITUTE, LLC454449408 - (MD) COLUMBIA SURGICAL INSTITUTE LLCMDAmbulatory Surgical Clinic/Center (261QA1903X)
United
45388$840.001467128819 - BLOOMINGTON ADVANCED SURGERY CENTER, LLC, BLOOMINGTON ADVANCED SURGERY CENTER871240828 - (IN) BLOOMINGTON ADVANCED SURGERY CENTER LLCINAmbulatory Surgical Clinic/Center (261QA1903X)
United
45388$297.001295793974 - SANTA LUCIA SURGICAL CENTER LLC201918525 - (FL) SANTA LUCIA SURGICAL CENTER LLCFLAmbulatory Surgical Clinic/Center (261QA1903X)
United
45388$565.001306134838 - ASC DEVELOPMENT COMPANY LLC203405773 - (MD) ASC DEVELOPMENT COMPANY LLCMDAmbulatory Surgical Clinic/Center (261QA1903X)
United
45388$394.001265455463 - THE ENDOSCOPY CENTER AT BEL AIR470863243 - (MD) THE ENDOSCOPY CENTER AT BEL AIRMDAmbulatory Surgical Clinic/Center (261QA1903X)
United
45388$2382.001801987805 - ENDO SURGI CENTER OF OLD BRIDGE LLC223679920 - (NJ) ENDO-SURGI CENTER OF OLD BRIDGE, LLCNJAmbulatory Surgical Clinic/Center (261QA1903X)
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist

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CPT 45388 vs. Other Surgical Procedures on the Digestive System Codes

The CPT 45388 code is part of the Surgery services used for Surgical Procedures on the Digestive System. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The CPT 45388 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
45346-CPTHighSigmoidoscopy, Flexible; Diagnostic, Including Collection Of Specimen(S) By Brushing Or Washing, When Performed With Ablation Of Tumor(S), Polyp(S), Or Other Lesions(S) Includ
45378-CPTModerateColonoscopy Flexible Diagnostic Including Collection Of Specimen(S) By Brushing Or Washing When Performed (Separate Procedure) (Desc Revised 01/01/15)
45380-CPTModerateColonoscopy, Fiberoptic, Beyond Splenic Flexure; For Biopsy And/Or Collection Of Specimen By Brushing Or Washing
45388-CPTHighColonoscopy, Flexible; Diagnostic, Including Collection Of Specimens By Brushing Or Washing, When Performed, With Ablation Of Tumors, Polyss, Or Other Lesionss Includ

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 45388. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 45388 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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