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CPT 45388 Fee Schedule

Medicare rates as of October 2026

CPT 45388 is classified under Surgery, in the Surgical Procedures on the Digestive System subgroup.

Colonoscopy To Remove Tissue, An Exam Of The Lower Part Of The Large Intestine (Colon) Using A Scope (Colonoscopy). The Procedure Removes Abnormal Tissue Growths Such As Tumors Or Polyps.
Key FactDetail
Service Type

Surgery

Surgical Procedures on the Digestive System

Common Place of Service

24 - Ambulatory Surgical Center

22 - On Campus Outpatient Hospital

Common Modifiers

PT - Colorectal cancer screening test; converted to diagnostic test or other procedure

33 - Preventive Services

Complexity LevelHigh
Medicare Fee Schedule$2,659.38 national non-facility rate (2026) · View Medicare rates for 45388
Medicaid Fee Schedule$2,105.135 median of the 8 states in the free preview · View Medicaid rates for 45388

National average reimbursement for CPT 45388 by major payers:

BCBS / Anthem logo

$2,357.42

BCBS / Anthem

UnitedHealthcare logo

$2,725.34

UnitedHealthcare

Aetna logo

$3,186.72

Aetna

Cigna logo

$726.56

Cigna

Compare published rates across providers.

Choose a payer to see a sample of rates for CPT 45388.

CPT 45388
5 of 25 sample ratesHigher to lower in this preview
  1. Court Street Surgery Center, Lp

    CAAmbulatory Surgical Clinic/CenterNPI 1477552768Tax ID 30-0197423

    $3,513.00Published rate
  2. Dreyer Ambulatory Surgery Center, LLC

    Dreyer Ambulatory Surgery Center LLC

    ILAmbulatory Surgical Clinic/CenterNPI 1396896684Tax ID 36-3890298

    $1,525.00Published rate
  3. Comprehensive Digestive Surgicenter, LLC, Comprehensive Digestive Surgical Center

    Comprehensive Digestive Surgicenter LLC

    NVAmbulatory Surgical Clinic/CenterNPI 1164012142Tax ID 85-4015524

    $945.00Published rate
  4. I Care Center LLC, Central Indiana Surgery Center

    Icare Center Dba Central Indiana Surgery Center, LLC

    INAmbulatory Surgical Clinic/CenterNPI 1174615702Tax ID 35-1937200

    $651.00Published rate
  5. The Endoscopy Center At Bel Air

    MDAmbulatory Surgical Clinic/CenterNPI 1265455463Tax ID 47-0863243

    $394.00Published rate

National sample. Rates vary by location, specialty, and contract.

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CPT 45388 vs. Other Surgical Procedures on the Digestive System Codes

The table lists codes related to 45388. Select one to see its fee schedule.

CodeComplexityDescription
45346-CPTHighColonoscopy To Remove Tissue, An Exam Of The Lower Part Of The Large Intestine (Colon) Using A Scope (Sigmoidoscopy). The Procedure Removes Abnormal Tissue Growths Such As Tumors Or Polyps.
45380-CPTModerateIntestinal Exam (Colonoscopy), An Exam Of The Lower Part Of The Intestine (Colon) Using A Scope (Colonoscopy). The Procedure May Include Collection Of Cells Or Tissue For Testing (Biopsy).
45384-CPTModerateColonoscopy Flexible Proxima, Colonoscopy Flexible Proximal To Splenic Flexure Withremoval Of Tumor(S) Polyp(S) Or Other Lesion(S) By Hot Biopsy Forceps Or Bipolar Cautery
45388-CPTHighColonoscopy To Remove Tissue, An Exam Of The Lower Part Of The Large Intestine (Colon) Using A Scope (Colonoscopy). The Procedure Removes Abnormal Tissue Growths Such As Tumors Or Polyps.

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 45388. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 45388 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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