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CPT 46221 Fee Schedule

Last Verified: November 2025

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Hemorrhoidectomy, Internal, By Rubber Band Ligation(S)
Key FactDetail
Service Type

Surgery

Surgical Procedures on the Digestive System

Common Place of Service

11 - Office

24 - Ambulatory Surgical Center

Common Modifiers

None

58 - Staged or related procedure during postoperative period

59 - Distinct Procedural Service

Complexity LevelModerate
CMS$278.83 Physician Fee Schedule

National average reimbursement for CPT 46221 by major payers:

bcbs

$324.60

uhc

$341.71

aetna

$384.62

cigna

$452.82

Preview provider-level rates for...
For billing codeCPT 46221
PayerCodeRateNPITax IDStateSpecialty

Select a payer to view fee schedule data

Choose a payer from the options above to see rates for CPT 46221

United
46221$520.001841342789 - SURGERY CENTER JV, THE SURGERY CENTER OF HUNTSVILLE621230866 - (AL) THE SURGERY CENTER OF HUNTSVILLEALAmbulatory Surgical Clinic/Center (261QA1903X)
United
46221$767.001346205481 - BLOOMINGTON EYE INSTITUTE LLC371361486 - (IL) BLOOMINGTON EYE INSTITUTE LLCILAmbulatory Surgical Clinic/Center (261QA1903X)
United
46221$1155.001760794218 - NSC MANAGEMENT COMPANY, INC., ENDEAVOR SURGICAL CENTER954683164 - (CA) NORTHRIDGE SURGERY AND PAIN MANAGEMENT CENTER, INC.CAAmbulatory Surgical Clinic/Center (261QA1903X)
United
46221$1886.001982680492 - ROCKLAND SURGICAL PROJECT, LLC, RAMAPO VALLEY SURGICAL CENTER200580403 - (NJ) ROCKLAND SURGICAL PROJECT LLCNJAmbulatory Surgical Clinic/Center (261QA1903X)
United
46221$523.001275507527 - ENDOSCOPY CENTER OF NORTHWEST CONNECTICUT61609993 - (CT) ENDOSCOPY CENTER OF NORTHWEST CTCTAmbulatory Surgical Clinic/Center (261QA1903X)
United
46221$285.001871644823 - PERLOW FACILITY, LLC251926011 - (GA) PERLOW FACILITY LLCGAAmbulatory Surgical Clinic/Center (261QA1903X)
United
46221$1367.001285870303 - LAPORTE MEDICAL GROUP SURGICAL CENTER, LLC260505795 - (IN) LAPORTE MEDICAL GROUP SURGICAL CENTER LLCINAmbulatory Surgical Clinic/Center (261QA1903X)
United
46221$1158.001043803877 - PALM BEACH INTERNATIONAL SURGERY CENTER LLC, PALM BEACH INTERNATIONAL SURGERY CENTER AT THE PALEY INSTITUTE384092545 - (FL) PALM BEACH INTERNATIONAL SURGERY CENTER LLCFLAmbulatory Surgical Clinic/Center (261QA1903X)
United
46221$392.001740491422 - PV PENINSULA PLASTIC SURGERY CENTER208545497 - (CA) PV PENINSULA PLASTIC SURGERY CENTERCAAmbulatory Surgical Clinic/Center (261QA1903X)
United
46221$913.001831117704 - MEDICAL HEIGHTS SURGERY CENTER, INC., KENTUCKY SURGERY CENTER843280181 - (KY) BAPTIST HEALTH SURGERY CENTER, LKYAmbulatory Surgical Clinic/Center (261QA1903X)
United
46221$667.001114584786 - ECCS ACQUISITION COMPANY LLC352656413COAmbulatory Surgical Clinic/Center (261QA1903X)
United
46221$525.001285333914 - ARIZONA SURGICAL SPECIALISTS CENTER, LLC, ARIZONA SURGICAL SPECIALISTS CENTER, LLC - SCOTTSDALE760737449 - (AZ) ARIZONA SURGICAL SPECIALISTS CENTER LLCAZAmbulatory Surgical Clinic/Center (261QA1903X)
United
46221$4215.001851354377 - MANATEE SURGICARE LTD752367622 - (FL) MANATEE SURGICARE LTDFLAmbulatory Surgical Clinic/Center (261QA1903X)
United
46221$1155.001497201867 - ABILENE CENTER FOR ORTHOPEDIC AND MULTISPECIALTY SURGERY, L.L.C.813619502 - (TX) ABILENE CENTER FOR ORTHOPEDIC AND MULTISPECIALTY SURGERY LLCTXAmbulatory Surgical Clinic/Center (261QA1903X)
United
46221$384.001629045133 - MONTICELLO COMMUNITY SURGERY CENTER, LLC, UVA HEALTH SURGICAL CARE RIVERSIDE113656095 - (VA) MONTICELLO COMMUNITY SURGERYVAAmbulatory Surgical Clinic/Center (261QA1903X)
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist

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CPT 46221 vs. Other Surgical Procedures on the Digestive System Codes

The CPT 46221 code is part of the Surgery services used for Surgical Procedures on the Digestive System. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The CPT 46221 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
46220-CPTModerateRemoval Of Single External Benign Growth (Papilla Or Tag) Of Anus
46221-CPTModerateHemorrhoidectomy, Internal, By Rubber Band Ligation(S)
46230-CPTModerateRemoval Of Multiple External Benign Growths (Papillas Or Tags) Of Anus
46250-CPTModerateHemorrhoidectomy,External,2 Or More Columns Or Groups

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 46221. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 46221 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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