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See a sample rate comparisonCPT 80333 Fee Schedule
Last Verified: October 2026
Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.
Antidepressant Drug Screening, This Screening Measures The Amount Of Antidepressants Present In A Blood Or Urine Sample.
| Key Fact | Detail |
|---|---|
| Service Type | Pathology and Laboratory Procedures Therapeutic Drug Assays |
| Common Place of Service | 81 - Independent Laboratory 11 - Office |
| Common Modifiers | 90 - Reference Laboratory TC - Technical component |
| Complexity Level | Low |
| Medicare Fee Schedule | View Medicare rates for 80333 |
| Medicaid Fee Schedule | $16.66 median of the 5 states in the free preview · View Medicaid rates for 80333 |
National average reimbursement for CPT 80333 by major payers:
$35.27
$28.44
$2.26
$57.46
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CPT 80333
5 of 25 sample ratesHigher to lower in this preview
Chu Chen
Merrimack Valley Pediatric Associates, Inc.
$14.90Published rateClhg-Dequincy, LLC
Clhgdequincy LLC
$13.27Published rateFairway Medical Center, LLC, Avala
Fairway Medical Center, LLC Dba Avala
$13.27Published rateClhg-Leesville, Byrd Regional Hospital
$8.85Published rateCaldwell Memorial Hospital Inc
Caldwell Memorial Hospital, Inc.
$6.19Published rate
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See a sample payer proposalCPT 80333 vs. Other Therapeutic Drug Assays Codes
The CPT 80333 code is part of the Pathology and Laboratory Procedures services used for Therapeutic Drug Assays. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.
The CPT 80333 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.
| Code | Complexity | Description |
|---|---|---|
| 80330-CPT | Low | Analgesic Drug Screening, This Screening Measures The Amount Of Analgesics Present In A Blood Or Urine Sample. |
| 80331-CPT | Low | Analgesic Drug Screening, This Screening Measures The Amount Of Analgesics Present In A Blood Or Urine Sample. |
| 80332-CPT | Low | Antidepressant Drug Screening, This Screening Measures The Amount Of Antidepressants Present In A Blood Or Urine Sample. |
| 80333-CPT | Low | Antidepressant Drug Screening, This Screening Measures The Amount Of Antidepressants Present In A Blood Or Urine Sample. |
What is a fee schedule?
A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 80333. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.
Understanding the 80333 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.
Factors that affect fee schedules
Medicare & Medicaid Rates
Government-set reimbursement amounts
Private Insurance Rates
Negotiated rates between providers and insurance companies
Geographic Location
Costs may be higher in urban areas.
Provider Type
Hospital providers may have different rates than private practice.
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