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CPT 80346 Fee Schedule

Last Verified: October 2026

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Sedative Therapy Monitoring, Benzodiazepines Are A Class Of Sedatives That Can Have Strong Effects. A Blood Analysis Helps To Determine A Therapeutic Dose And Can Show Other Issues Such As Overdosing.
Key FactDetail
Service Type

Pathology and Laboratory Procedures

Therapeutic Drug Assays

Common Place of Service

81 - Independent Laboratory

11 - Office

Common Modifiers

90 - Reference Laboratory

26 - Professional component

Complexity LevelLow
Medicare Fee ScheduleView Medicare rates for 80346
Medicaid Fee Schedule$21.88 median of the 6 states in the free preview · View Medicaid rates for 80346

National average reimbursement for CPT 80346 by major payers:

bcbs

$23.48

uhc

$15.51

aetna

$2.32

cigna

$55.62

Compare published rates across providers.

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CPT 80346
5 of 25 sample ratesHigher to lower in this preview
  1. Chu Chen

    Merrimack Valley Pediatric Associates, Inc.

    MAPediatrics PhysicianNPI 1073502985Tax ID 42-484572

    $63.36Published rate
  2. Baycare Home Care, Inc.

    Baycare Home Care Inc

    FLHome Health AgencyNPI 1952309171Tax ID 59-3582520

    $17.45Published rate
  3. Chu Chen

    Merrimack Valley Pediatric Associates, Inc.

    MAPediatrics PhysicianNPI 1073502985Tax ID 42-484572

    $16.11Published rate
  4. Texas Spine And Joint Hospital, LLC, Baylor Scott & White Tx Spine & Joint Hos Sur Ctr

    Texas Spine And Joint Hospital

    TXGeneral Acute Care HospitalNPI 1942292255Tax ID 75-2951355

    $10.36Published rate
  5. Ascension Seton, Ascension Seton Medical Center Austin

    Ascension Seton

    TXGeneral Acute Care HospitalNPI 1164526786Tax ID 74-1109643

    $9.10Published rate

National sample. Rates vary by location, specialty, and contract.

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CPT 80346 vs. Other Therapeutic Drug Assays Codes

The CPT 80346 code is part of the Pathology and Laboratory Procedures services used for Therapeutic Drug Assays. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The CPT 80346 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
80336-CPTLowAntidepressant Drug Screening, This Screening Measures The Amount Of Antidepressants Present In A Blood Or Urine Sample.
80337-CPTLowAntidepressant Drug Screening, This Screening Measures The Amount Of Antidepressants Present In A Blood Or Urine Sample.
80346-CPTLowSedative Therapy Monitoring, Benzodiazepines Are A Class Of Sedatives That Can Have Strong Effects. A Blood Analysis Helps To Determine A Therapeutic Dose And Can Show Other Issues Such As Overdosing.
80347-CPTLowSedative Therapy Monitoring, Benzodiazepines Are A Class Of Sedatives That Can Have Strong Effects. A Blood Analysis Helps To Determine A Therapeutic Dose And Can Show Other Issues Such As Overdosing.

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 80346. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 80346 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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