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See a sample rate comparisonHealthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.
| Key Fact | Detail |
|---|---|
| Service Type | Pathology and Laboratory Procedures Therapeutic Drug Assays |
| Common Place of Service | 81 - Independent Laboratory 11 - Office |
| Common Modifiers | 90 - Reference Laboratory |
| Complexity Level | Low |
| Medicare Fee Schedule | View Medicare rates for 80351 |
| Medicaid Fee Schedule | $19.62 median of the 4 states in the free preview · View Medicaid rates for 80351 |
National average reimbursement for CPT 80351 by major payers:

$31.57

$29.36

$1.61

$54.63
Choose a payer to see a sample of rates for CPT 80351.
Hospital Service District #2 Of Lasalle Parish, Lasalle General Hospital
Hospital Service District 2 Of Lasalle Parish
Piedmont Walton Hospital Inc
Cartersville Medical Center LLC, Cartersville Medical Center
Cartersville Medical Center LLC
Fairfield Hospital District, Freestone Medical Center
Palo Pinto County Hospital District, Palo Pinto General Hospital
Choose your state and specialty to build a report from payer-published rates.
Rate Benchmarking
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See a sample rate comparisonPayer Contract Negotiation
Use your fee schedule and market benchmarks to set target rates and draft a letter for your payer.
See a sample payer proposalCPT 80351 vs. Other Therapeutic Drug Assays Codes
The CPT 80351 code is part of the Pathology and Laboratory Procedures services used for Therapeutic Drug Assays. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.
The CPT 80351 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.
| Code | Complexity | Description |
|---|---|---|
| 80342-CPT | Low | Antipsychotic Drug Screening, This Screening Measures The Amount Of Antipsychotics Present In A Blood Or Urine Sample. |
| 80349-CPT | Low | Cannabinoid Drug Screening, This Test Measures The Amount Of Cannabinoids Present In Blood And Urine Samples. |
| 80350-CPT | Low | Cannabinoid Drug Screening, This Test Measures The Amount Of Cannabinoids Present In Blood And Urine Samples. |
| 80351-CPT | Low | Cannabinoid Drug Screening, This Test Measures The Amount Of Cannabinoids Present In Blood And Urine Samples. |
What is a fee schedule?
A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 80351. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.
Understanding the 80351 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.
Factors that affect fee schedules
Medicare & Medicaid Rates
Government-set reimbursement amounts
Private Insurance Rates
Negotiated rates between providers and insurance companies
Geographic Location
Costs may be higher in urban areas.
Provider Type
Hospital providers may have different rates than private practice.
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