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CPT 80377 Fee Schedule

Last Verified: November 2025

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Drug(S) Or Substance(S), Definitive, Qualitative Or Quantitative, Not Otherwise Specified; 7 Or More
Key FactDetail
Service Type

Pathology and Laboratory Procedures

Therapeutic Drug Assays

Common Place of Service

81 - Independent Laboratory

11 - Office

Common Modifiers

None

90 - Reference Laboratory

26 - Professional component

Complexity LevelLow

National average reimbursement for CPT 80377 by major payers:

bcbs

$21.18

uhc

$14.93

aetna

$2.47

cigna

$39.38

Preview provider-level rates for...
For billing codeCPT 80377
PayerCodeRateNPITax IDStateSpecialty

Select a payer to view fee schedule data

Choose a payer from the options above to see rates for CPT 80377

United
80377$10.101013964113 - EYECARE ASSOCIATES PC930590581 - EYECARE ASSOCIATES PCOROphthalmology Physician (207W00000X)
United
80377$10.151790057420 - BAMA HEART DOC, P.C., ALABAMA HEART AND VASCULAR MEDICINE451471722 - (AL) BAMA HEART DOC, PC DBA ALABAMA HEART & VASCULAR MEDICINEALInterventional Cardiology Physician (207RI0011X)
United
80377$11.531851400485 - GEORGE HEMSTREET451471722 - (AL) BAMA HEART DOC, PC DBA ALABAMA HEART & VASCULAR MEDICINEALInterventional Cardiology Physician (207RI0011X)
United
80377$16.951972501252 - BAYCARE HOME CARE, INC.593582520 - (FL) BAYCARE HOME CARE INCFLHome Health Agency (251E00000X)
United
80377$16.951134127301 - BAYCARE HOME CARE, INC.593582520 - (FL) BAYCARE HOME CARE INCFLHome Health Agency (251E00000X)
United
80377$10.101891774519 - LEON HOME HEALTH, LLC, LEON AT HOME261288029FLHome Health Agency (251E00000X)
United
80377$10.151679845531 - DANA HEMSTREET451471722 - (AL) BAMA HEART DOC, PC DBA ALABAMA HEART & VASCULAR MEDICINEALFamily Nurse Practitioner (363LF0000X)
United
80377$10.151740453000 - GRAHAM REGIONAL MEDICAL CENTER, GRAHAM GENERAL HSOPITAL PHYSICIANS751609992TXGeneral Acute Care Hospital (282N00000X)
United
80377$10.721972590602 - PALO PINTO COUNTY HOSPITAL DISTRICT, PALO PINTO GENERAL HOSPITAL751256948TXGeneral Acute Care Hospital (282N00000X)
United
80377$10.151093753386 - WILLAMETTE COMMUNITY HEALTH SOLUTIONS, CASCADE HEALTH SOLUTIONS930421470ORCommunity Based Hospice Care Agency (251G00000X)
United
80377$10.361447259627 - TYLER COUNTY HOSPITAL DISTRICT746067306TXGeneral Acute Care Hospital (282N00000X)
United
80377$10.131740453000 - GRAHAM REGIONAL MEDICAL CENTER, GRAHAM GENERAL HSOPITAL PHYSICIANS463113489TXGeneral Acute Care Hospital (282N00000X)
United
80377$25.521932729803 - DALLAS VAMC756108647TXGeneral Acute Care Hospital (282N00000X)
United
80377$13.181164776688 - NICOLE SCHWAB362925195 - ALLERGY & ASTHMA OF DUPAGE, S.C.ILFamily Nurse Practitioner (363LF0000X)
United
80377$10.151306540380 - KARLIE RYAN451471722 - (AL) BAMA HEART DOC, PC DBA ALABAMA HEART & VASCULAR MEDICINEALFamily Nurse Practitioner (363LF0000X)
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist

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CPT 80377 vs. Other Therapeutic Drug Assays Codes

The CPT 80377 code is part of the Pathology and Laboratory Procedures services used for Therapeutic Drug Assays. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The CPT 80377 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
80345-CPTLowLab Tests Other Nonmedicare Fee Schedule
80366-CPTLowLab Tests Other Nonmedicare Fee Schedule
80370-CPTLowDefinitive Drug Testing; Skeletal Muscle Relaxants; 3 Or More
80377-CPTLowDrug(S) Or Substance(S), Definitive, Qualitative Or Quantitative, Not Otherwise Specified; 7 Or More

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 80377. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 80377 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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