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CPT 81109 Fee Schedule

Last Verified: September 2026

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Human Platelet Antigen 5 Genot, Human Platelet Antigen 5 Genotyping (Hpa-5) Itga2(Integrin Alpha 2 [Cd49b Alpha 2 Subunit Of Vla -2 Receptor] [Gpia]) (Eg Neonatal Alloimmune Thrombocytopenia [Nait] Post-Transfusion Purpura) Gene Analysis Common Variant (Eg Hpa-5ab (K505e))Hpa-3ab (I843s)
Key FactDetail
Service Type

Pathology and Laboratory Procedures

Molecular Pathology Procedures

Common Place of Service

81 - Independent Laboratory

22 - On Campus Outpatient Hospital

Common Modifiers

None

90 - Reference Laboratory

91 - Repeat Lab Test

Complexity LevelLow
Medicare Fee ScheduleView Medicare rates for 81109
Medicaid Fee ScheduleView Medicaid rates for 81109

National average reimbursement for CPT 81109 by major payers:

bcbs

$124.99

uhc

$83.60

aetna

$121.80

cigna

$191.72

Compare published rates across providers.

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CPT 81109
5 of 25 sample ratesHigher to lower in this preview
  1. Chu Chen

    Merrimack Valley Pediatric Associates, Inc.

    MAPediatrics PhysicianNPI 1073502985Tax ID 42-484572

    $268.88Published rate
  2. Baycare Home Care, Inc.

    Baycare Home Care Inc

    FLHome Health AgencyNPI 1720087513Tax ID 59-3582520

    $111.26Published rate
  3. Bradley Weisner

    Urology Specialists Of The Carolinas, PLLC

    NCUrology PhysicianNPI 1619910627Tax ID 56-2107759

    $75.45Published rate
  4. Caldwell Memorial Hospital Inc

    Caldwell Memorial Hospital, Inc.

    LAGeneral Acute Care HospitalNPI 1134126659Tax ID 72-0878037

    $63.36Published rate
  5. E And A Medical On The Go Healthcare Of South Florida LLC, E And A Healthcare On The Go

    E And A Medical On The Go Healthcare Of South Florida LLC

    FLHome Health AgencyNPI 1598375651Tax ID 83-2289173

    $42.77Published rate

National sample. Rates vary by location, specialty, and contract.

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CPT 81109 vs. Other Molecular Pathology Procedures Codes

The CPT 81109 code is part of the Pathology and Laboratory Procedures services used for Molecular Pathology Procedures. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The CPT 81109 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
81107-CPTLowHuman Platelet Antigen 3 Genot, Human Platelet Antigen 3 Genotyping (Hpa-3) Itga2b (Integrin Alpha 2b [Platelet Glycoprotein Iib Of Iibiiia Complex] Antigen Cd41 [Gpiib]) (Eg Neonatal Alloimmune Thrombocytopenia [Nait] Post-Transfusion Purpura) Gene Analysis Common Varianthpa-3ab (I843s)
81108-CPTLowHuman Platelet Antigen 4 Genot, Human Platelet Antigen 4 Genotyping (Hpa-4) Itgb3(Integrin Beta 3 [Platelet Glycoprotein Iiia] A Ntigen Cd61 [Gpiiia]) (Eg Neonatal Alloimmune Thrombocytopenia [Nait] Post-Transfusion Purpura) Gene Analysis Common Variant Hpa-4ab (R143q) Hpa-3ab (I843s)
81109-CPTLowHuman Platelet Antigen 5 Genot, Human Platelet Antigen 5 Genotyping (Hpa-5) Itga2(Integrin Alpha 2 [Cd49b Alpha 2 Subunit Of Vla -2 Receptor] [Gpia]) (Eg Neonatal Alloimmune Thrombocytopenia [Nait] Post-Transfusion Purpura) Gene Analysis Common Variant (Eg Hpa-5ab (K505e))Hpa-3ab (I843s)
81110-CPTLowHuman Platelet Antigen 6 Genot, Human Platelet Antigen 6 Genotyping (Hpa-6w) Itgb3 (Integrin Beta 3 [Platelet Glycoprotein Iiia Antigen Cd61] [Gpiiia]) (Eg Neonatal Alloimmune Thrombocytopenia [Nait] Post-Transfusion Purpura) Gene Analysis Common Variant Hpa-6ab (R489q) Hpa-3ab (I843s)

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 81109. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 81109 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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