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CPT 81164 Fee Schedule

Last Verified: September 2026

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Key FactDetail
Service Type

Pathology and Laboratory Procedures

Molecular Pathology Procedures

Common Place of Service

81 - Independent Laboratory

Common Modifiers

None

59 - Distinct Procedural Service

33 - Preventive Services

Complexity LevelModerate
Medicare Fee ScheduleView Medicare rates for 81164
Medicaid Fee ScheduleView Medicaid rates for 81164

National average reimbursement for CPT 81164 by major payers:

bcbs

$438.92

uhc

$358.11

aetna

$542.11

cigna

$856.22

CPT 81164 vs. Other Molecular Pathology Procedures Codes

The CPT 81164 code is part of the Pathology and Laboratory Procedures services used for Molecular Pathology Procedures. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The CPT 81164 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
81162-CPTHigh
Brca1 2 Gen Full Seq Dup Del, Brca1 Brca1 Dna Repair Associated Brca2 Brca2 Dna Repair Associated Eg Hereditary Breast And Ovarian Cancer Gene Analysis Full Sequence Analysis And Full Duplication Deletion Analysis Ie Detection Of Large Gene Rearrangements
81163-CPTModerate
Brca1 2 Gene Full Seq Alys, Brca1 Brca1 Dna Repair Associated Brca2 Brca2 Dna Repair Associated Eg Hereditary Breast And Ovarian Cancer Gene Analysis Full Sequence Analysis
81164-CPTModerate
Brca1 2 Gen Ful Dup Del Alys, Brca1 Brca1 Dna Repair Associated Brca2 Brca2 Dna Repair Associated Eg Hereditary Breast And Ovarian Cancer Gene Analysis Full Duplication Deletion Analysis Ie Detection Of Large Gene Rearrangements
81165-CPTModerate
Genetic Test For Cancer, A Lab Analysis Of Genetic Material That Can Indicate Various Types Of Cancer. Types Of Analysis Include Gene Variants Full Sequence Analysis Or Breakpoints.

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 81164. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 81164 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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