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CPT 81261 Fee Schedule

Last Verified: January 2026

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Igh@ (Immunoglobin Heavy Chain Locus) (Eg Leukemias And Lymphomas B-Cell) Gene Re Arrangement Analysis To Detect Abnormal Clonal Population(S); Amplified Methodology (Eg Polymerase Chain Reation)
Key FactDetail
Service Type

Pathology and Laboratory Procedures

Molecular Pathology Procedures

Common Place of Service

81 - Independent Laboratory

22 - On Campus Outpatient Hospital

Common Modifiers

None

59 - Distinct Procedural Service

26 - Professional component

Complexity LevelLow
Medicare Fee ScheduleView Medicare rates for 81261

National average reimbursement for CPT 81261 by major payers:

bcbs

$165.99

uhc

$141.99

aetna

$199.67

cigna

$321.32

Preview provider-level rates for...
For billing codeCPT 81261
PayerCodeRateNPITax IDStateSpecialty

Select a payer to view fee schedule data

Choose a payer from the options above to see rates for CPT 81261

United
81261$178.191225450588 - PARISH HOSPITAL SERVICE DISTRICT FOR THE PARISH OF ORLEANS, NEW ORLEANS EAST HOSPITAL273335876LAGeneral Acute Care Hospital (282N00000X)
United
81261$114.061023438009 - MOLLY MCINTOSH593140335 - BAYCARE MEDICAL GROUP INCFLHome Health Agency (251E00000X)
United
81261$271.321255478004 - CHRISTOPHER RAIO112050523 - ST FRANCIS HOSPITALNYEmergency Medicine Physician (207P00000X)
United
81261$108.041366400376 - SUNRISE HOME HEALTH CARE INC.650307774 - (FL) SUNRISE HOME HEALTH CARE INCFLHome Health Agency (251E00000X)
United
81261$261.351255478004 - CHRISTOPHER RAIO111635088 - MERCY MEDICAL CENTERNYEmergency Medicine Physician (207P00000X)
United
81261$197.991073502985 - CHU CHEN42484572 - MERRIMACK VALLEY PEDIATRIC ASSOCIATES, INC.MAPediatrics Physician (208000000X)
United
81261$200.271821097627 - BAYCARE HOME CARE, INC.593582520 - (FL) BAYCARE HOME CARE INCFLHome Health Agency (251E00000X)
United
81261$148.551053725994 - HANS HENRIQUEZ363950044 - PROGRESSIVE MEDICAL CENTER, S.C.ILInternal Medicine Physician (207R00000X)
United
81261$135.061811000177 - CHARLESTON RADIOLOGISTS PA570634747 - CHARLESTON RADIOLOGISTS, P.A.SCDiagnostic Radiology Physician (2085R0202X)
United
81261$261.351255478004 - CHRISTOPHER RAIO113438973 - ST JOSEPH HOSPITALNYEmergency Medicine Physician (207P00000X)
United
81261$83.161366428401 - AARON ASKEW931261079 - THE ORTHOPEDIC AND NEUROSURGICAL CENTER OF THE CASCADESOROrthopaedic Trauma Physician (207XX0801X)
United
81261$106.911255478004 - CHRISTOPHER RAIO111635088 - MERCY MEDICAL CENTERNYEmergency Medicine Physician (207P00000X)
United
81261$128.691871162834 - AHS HOSPITAL CORP, AHS CONSOLIDATED LABS521958352 - ATLANTIC HEALTH SYSTEM INCNJClinical Medical Laboratory (291U00000X)
United
81261$294.101023335643 - VINEETHA ALIAS521958352 - ATLANTIC HEALTH SYSTEM INCPAPediatrics Physician (208000000X)
United
81261$271.321255478004 - CHRISTOPHER RAIO111888924 - GOOD SAMARITAN HOSPTIAL MEDICAL CENTERNYEmergency Medicine Physician (207P00000X)
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist

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CPT 81261 vs. Other Molecular Pathology Procedures Codes

The CPT 81261 code is part of the Pathology and Laboratory Procedures services used for Molecular Pathology Procedures. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The CPT 81261 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
81251-CPTLowGba (Glucosidase, Beta, Acid) (Eg, Gaucher Disease) Gene Analysis, Common Variants (Eg, N370s, 84gg, L444p, Ivs2+1g>A)
81252-CPTLowGjb2 (Gap Junction Protein Beta 2 26kda; Connexin 26) (Eg. Nonsyndromic Hearing Loss) Gene Analysis; Full Gene Sequence
81260-CPTLowIkbkap (Inhibitor Of Kappa Light Polypeptide Gene Enhancer In B-Cells, Kinase Complex-Associated Protein) (Eg, Familial Dysautonomia) Gene Analysis, Common Variants (Eg, 2507+6t>C, R696p)
81261-CPTLowIgh@ (Immunoglobin Heavy Chain Locus) (Eg Leukemias And Lymphomas B-Cell) Gene Re Arrangement Analysis To Detect Abnormal Clonal Population(S); Amplified Methodology (Eg Polymerase Chain Reation)

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 81261. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 81261 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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