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CPT 81266 Fee Schedule

Last Verified: September 2026

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Str Markers Spec Anal Addl, Comparative Analysis Using Short Tandem Repeat Str Markers Each Additional Specimen Eg Additional Cord Blood Donor Additional Fetal Samples From Different Cultures Or Additional Zygosity In Multiple Birth Pregnancies List Separately In Addition To Code For Primary Procedure
Key FactDetail
Service Type

Pathology and Laboratory Procedures

Molecular Pathology Procedures

Common Place of Service

81 - Independent Laboratory

11 - Office

Common Modifiers

None

59 - Distinct Procedural Service

XU - Unusual Non-Overlapping Service

Complexity LevelModerate
Medicare Fee ScheduleView Medicare rates for 81266
Medicaid Fee ScheduleView Medicaid rates for 81266

National average reimbursement for CPT 81266 by major payers:

bcbs

$228.41

uhc

$186.70

aetna

$269.58

cigna

$461.55

Compare published rates across providers.

Choose a payer to see a sample of rates for CPT 81266.

CPT 81266
5 of 25 sample ratesHigher to lower in this preview
  1. Donald Hoelzel

    Atlantic Health System Inc

    NJPediatrics PhysicianNPI 1194797456Tax ID 52-1958352

    $407.48Published rate
  2. Chu Chen

    Merrimack Valley Pediatric Associates, Inc.

    MAPediatrics PhysicianNPI 1073502985Tax ID 42-484572

    $304.81Published rate
  3. Michael Shuler

    Athens Orthopedic Clinic, PA

    GAOrthopaedic Hand Surgery PhysicianNPI 1497944565Tax ID 58-1076549

    $182.89Published rate
  4. Ann Steck

    Toledo Hospital

    OHFamily Medicine PhysicianNPI 1033320049Tax ID 34-4428256

    $164.29Published rate
  5. Progressive Emergency Physicians PLLC

    NYMulti-Specialty GroupNPI 1588098172Tax ID 46-3316332

    $110.99Published rate

National sample. Rates vary by location, specialty, and contract.

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CPT 81266 vs. Other Molecular Pathology Procedures Codes

The CPT 81266 code is part of the Pathology and Laboratory Procedures services used for Molecular Pathology Procedures. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The CPT 81266 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
81265-CPTLowStr Markers Specimen Anal, Comparative Analysis Using Short Tandem Repeat Str Markers Patient And Comparative Specimen Eg Pre Transplant Recipient And Donor Germline Testing Post Transplant Non Hematopoietic Recipient Germline Eg Buccal Swab Or Other Germline Tissue Sample And Donor Testing Twin Zygosity Testing Or Maternal Cell Contamination Of Fetal Cells
81266-CPTModerateStr Markers Spec Anal Addl, Comparative Analysis Using Short Tandem Repeat Str Markers Each Additional Specimen Eg Additional Cord Blood Donor Additional Fetal Samples From Different Cultures Or Additional Zygosity In Multiple Birth Pregnancies List Separately In Addition To Code For Primary Procedure
81267-CPTLowChimerism Anal No Cell Selec, Chimerism Engraftment Analysis Post Transplantation Specimen Eg Hematopoietic Stem Cell Includes Comparison To Previously Performed Baseline Analyses Without Cell Selection
81268-CPTModerateChimerism Anal W Cell Select, Chimerism Engraftment Analysis Post Transplantation Specimen Eg Hematopoietic Stem Cell Includes Comparison To Previously Performed Baseline Analyses With Cell Selection Eg Cd3 Cd33 Each Cell Type

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 81266. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 81266 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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