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CPT 81269 Fee Schedule

Last Verified: September 2026

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Hba1hba2 (Alpha Globin 1 And, Hba1hba2 (Alpha Globin 1 And Alpha Globin 2) (Egalpha Thalassemia Hb Bart Hydrops Fetalis Syndro Me Hbh Disease) Gene Analysis Duplicationdeletion Variants (Eg Exon 12) Hpa-9ab (V837m)
Key FactDetail
Service Type

Pathology and Laboratory Procedures

Molecular Pathology Procedures

Common Place of Service

81 - Independent Laboratory

11 - Office

Common Modifiers

None

90 - Reference Laboratory

59 - Distinct Procedural Service

Complexity LevelLow
Medicare Fee ScheduleView Medicare rates for 81269
Medicaid Fee ScheduleView Medicaid rates for 81269

National average reimbursement for CPT 81269 by major payers:

bcbs

$156.79

uhc

$123.80

aetna

$190.18

cigna

$298.93

Compare published rates across providers.

Choose a payer to see a sample of rates for CPT 81269.

CPT 81269
5 of 25 sample ratesHigher to lower in this preview
  1. Chu Chen

    Merrimack Valley Pediatric Associates, Inc.

    MAPediatrics PhysicianNPI 1073502985Tax ID 42-484572

    $445.28Published rate
  2. Chu Chen

    Merrimack Valley Pediatric Associates, Inc.

    MAPediatrics PhysicianNPI 1073502985Tax ID 42-484572

    $202.40Published rate
  3. Christopher Raio

    St Joseph Hospital

    NYEmergency Medicine PhysicianNPI 1255478004Tax ID 11-3438973

    $121.44Published rate
  4. Aaron Askew

    The Orthopedic And Neurosurgical Center Of The Cascades

    OROrthopaedic Trauma PhysicianNPI 1366428401Tax ID 93-1261079

    $85.01Published rate
  5. Sunrise Home Health Care Inc.

    Sunrise Home Health Care Inc

    FLHome Health AgencyNPI 1366400376Tax ID 65-0307774

    $80.95Published rate

National sample. Rates vary by location, specialty, and contract.

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CPT 81269 vs. Other Molecular Pathology Procedures Codes

The CPT 81269 code is part of the Pathology and Laboratory Procedures services used for Molecular Pathology Procedures. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The CPT 81269 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
81268-CPTModerateChimerism Anal W Cell Select, Chimerism Engraftment Analysis Post Transplantation Specimen Eg Hematopoietic Stem Cell Includes Comparison To Previously Performed Baseline Analyses With Cell Selection Eg Cd3 Cd33 Each Cell Type
81269-CPTLowHba1hba2 (Alpha Globin 1 And, Hba1hba2 (Alpha Globin 1 And Alpha Globin 2) (Egalpha Thalassemia Hb Bart Hydrops Fetalis Syndro Me Hbh Disease) Gene Analysis Duplicationdeletion Variants (Eg Exon 12) Hpa-9ab (V837m)
81270-CPTLowBone Marrow Genetic Test, A Lab Analysis Of Genetic Material That Can Indicate A Problem With How Bone Marrow Creates Blood Cells. Types Of Analysis Include Gene Variants Full Sequence Analysis Or Breakpoints.
81271-CPTLowHuntington Disease Test, A Lab Analysis Of Genetic Material That Can Indicate Huntington Disease Which Causes The Breakdown Of Nerve Cells In The Brain.

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 81269. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 81269 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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