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CPT 81279 Fee Schedule

Last Verified: September 2026

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Key FactDetail
Service Type

Pathology and Laboratory Procedures

Molecular Pathology Procedures

Common Place of Service

81 - Independent Laboratory

11 - Office

Common Modifiers

None

90 - Reference Laboratory

GZ - Item or Service Expected to Be Denied as Not Reasonable and Necessary

Complexity LevelLow
Medicare Fee ScheduleView Medicare rates for 81279
Medicaid Fee ScheduleView Medicaid rates for 81279

National average reimbursement for CPT 81279 by major payers:

bcbs

$163.39

uhc

$113.42

aetna

$175.91

cigna

$275.76

CPT 81279 vs. Other Molecular Pathology Procedures Codes

The CPT 81279 code is part of the Pathology and Laboratory Procedures services used for Molecular Pathology Procedures. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The CPT 81279 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
81276-CPTLow
Kras (Kirsten Rat Sarcoma Vira, Kras (Kirsten Rat Sarcoma Viral Oncogene Homolog) (Eg Carcinoma) Gene Analysis Additional Variant(S) (Eg Codon 61 Codon 146)
81277-CPTHigh
Cytogenomic Neoplasia (Genome-, Cytogenomic Neoplasia (Genome-Wide) Microarray Analysis Interrogation Of Genomic Regions For Copy Number And Loss-Of-Heterozygosity Variants For Chromosomal Abnormalities
81278-CPTLow
Igh Bcl2 Translocation Alys, Igh Bcl2 T 14 18 Eg Follicular Lymphoma Translocation Analysis Major Breakpoint Region Mbr And Minor Cluster Region Mcr Breakpoints Qualitative Or Quantitative
81279-CPTLow
Jak2 (Janus Kinase 2) Targeted Sequence Analysis, Jak2 (Janus Kinase 2) (Eg Myeloproliferative Disorder) Targeted Sequence Analysis (Eg Exons 12 And 13)

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 81279. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 81279 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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