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See a sample rate comparisonHealthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.
| Key Fact | Detail |
|---|---|
| Service Type | Pathology and Laboratory Procedures Molecular Pathology Procedures |
| Common Place of Service | 81 - Independent Laboratory 21 - Inpatient Hospital |
| Common Modifiers | None XU - Unusual Non-Overlapping Service 26 - Professional component |
| Complexity Level | Low |
| Medicare Fee Schedule | View Medicare rates for 81287 |
| Medicaid Fee Schedule | View Medicaid rates for 81287 |
National average reimbursement for CPT 81287 by major payers:

$96.20

$65.44

$143.76

$210.79
Choose a payer to see a sample of rates for CPT 81287.
Merrimack Valley Pediatric Associates, Inc.
Merrimack Valley Pediatric Associates, Inc.
Mercy Medical Center
Baycare Home Care Inc
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Rate Benchmarking
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See a sample payer proposalCPT 81287 vs. Other Molecular Pathology Procedures Codes
The CPT 81287 code is part of the Pathology and Laboratory Procedures services used for Molecular Pathology Procedures. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.
The CPT 81287 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.
| Code | Complexity | Description |
|---|---|---|
| 81285-CPT | Moderate | Gene Test Friedreich Ataxia, Lab Analysis Of Genetic Material That Can Indicate Friedreich Ataxia A Disease That Causes Progressive Nervous System Damage And Movement Problems. |
| 81287-CPT | Low | Genetic Test For A Brain Tumor, A Lab Analysis Of Genetic Material That Can Indicate The Potential For Developing A Brain Tumor. Types Of Analysis Include Gene Variants Full Sequence Analysis Or Breakpoints. |
| 81288-CPT | Low | Mlh1 (Mutl Homolog 1 Colon Ca, Mlh1 (Mutl Homolog 1 Colon Cancer Nonpolyposis Type 2) (Eg Hereditary Non-Polyposis Colorectal Cancer Lynch Syndrome) Gene Analysis Promoter Methylation Analysis |
| 81289-CPT | Low | Gene Test Friedreich Ataxia, Lab Analysis Of Genetic Material That Can Indicate Friedreich Ataxia A Disease That Causes Progressive Nervous System Damage And Movement Problems. |
What is a fee schedule?
A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 81287. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.
Understanding the 81287 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.
Factors that affect fee schedules
Medicare & Medicaid Rates
Government-set reimbursement amounts
Private Insurance Rates
Negotiated rates between providers and insurance companies
Geographic Location
Costs may be higher in urban areas.
Provider Type
Hospital providers may have different rates than private practice.
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