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CPT 81307 Fee Schedule

Last Verified: September 2026

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Key FactDetail
Service Type

Pathology and Laboratory Procedures

Molecular Pathology Procedures

Common Place of Service

81 - Independent Laboratory

11 - Office

Common Modifiers

None

90 - Reference Laboratory

59 - Distinct Procedural Service

Complexity LevelModerate
Medicare Fee ScheduleView Medicare rates for 81307
Medicaid Fee ScheduleView Medicaid rates for 81307

National average reimbursement for CPT 81307 by major payers:

bcbs

$484.37

uhc

$190.40

aetna

$519.89

cigna

$946.84

CPT 81307 vs. Other Molecular Pathology Procedures Codes

The CPT 81307 code is part of the Pathology and Laboratory Procedures services used for Molecular Pathology Procedures. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The CPT 81307 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
81305-CPTLow
Myd88 Gene P Leu265pro Vrnt, Myd88 Myeloid Differentiation Primary Response 88 Eg Waldenstrom S Macroglobulinemia Lymphoplasmacytic Leukemia Gene Analysis P Leu265pro L265p Variant
81307-CPTModerate
Genetic Test For Cancer, A Lab Analysis Of Genetic Material That Can Indicate Breast Or Pancreatic Cancer. Types Of Analysis Include Gene Variants Full Sequence Analysis Or Breakpoints.
81308-CPTModerate
Genetic Test For Cancer, A Lab Analysis Of Genetic Material That Can Indicate Breast Or Pancreatic Cancer. Types Of Analysis Include Gene Variants Full Sequence Analysis Or Breakpoints.
81309-CPTModerate
Pik3ca Gene Trgt Seq Alys, Pik3ca Phosphatidylinositol 4 5 Biphosphate 3 Kinase Catalytic Subunit Alpha Eg Colorectal And Breast Cancer Gene Analysis Targeted Sequence Analysis Eg Exons 7 9 20

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 81307. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 81307 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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