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CPT 81325 Fee Schedule

Last Verified: January 2026

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Pmp22 (Peripheral Myelin Protein 22) (Eg, Charcot-Marie-Tooth, Hereditary Neuropathy With Liability To Pressure Palsies) Gene Analysis; Full Sequence Analysis
Key FactDetail
Service Type

Pathology and Laboratory Procedures

Molecular Pathology Procedures

Common Place of Service

81 - Independent Laboratory

11 - Office

Common Modifiers

None

90 - Reference Laboratory

59 - Distinct Procedural Service

Complexity LevelModerate
Medicare Fee ScheduleView Medicare rates for 81325

National average reimbursement for CPT 81325 by major payers:

bcbs

$679.87

uhc

$471.36

aetna

$697.74

cigna

$1,131.60

Preview provider-level rates for...
For billing codeCPT 81325
PayerCodeRateNPITax IDStateSpecialty

Select a payer to view fee schedule data

Choose a payer from the options above to see rates for CPT 81325

United
81325$414.801033320049 - ANN STECK344428256 - TOLEDO HOSPITALOHFamily Medicine Physician (207Q00000X)
United
81325$415.571255478004 - CHRISTOPHER RAIO111635088 - MERCY MEDICAL CENTERNYEmergency Medicine Physician (207P00000X)
United
81325$384.791811000177 - CHARLESTON RADIOLOGISTS PA570634747 - CHARLESTON RADIOLOGISTS, P.A.SCSingle Specialty Group (193400000X)
United
81325$323.221891774519 - LEON HOME HEALTH, LLC, LEON AT HOME261288029FLHome Health Agency (251E00000X)
United
81325$914.261255478004 - CHRISTOPHER RAIO112050523 - ST FRANCIS HOSPITALNYEmergency Medicine Physician (207P00000X)
United
81325$423.261851464549 - PROGRESSIVE MEDICAL CENTER SC363950044 - PROGRESSIVE MEDICAL CENTER, S.C.ILInternal Medicine Physician (207R00000X)
United
81325$567.521235122029 - BAYCARE HOME CARE, INC.593582520 - (FL) BAYCARE HOME CARE INCFLHome Health Agency (251E00000X)
United
81325$914.261255478004 - CHRISTOPHER RAIO111888924 - GOOD SAMARITAN HOSPTIAL MEDICAL CENTERNYEmergency Medicine Physician (207P00000X)
United
81325$768.811255478004 - CHRISTOPHER RAIO111888924 - GOOD SAMARITAN HOSPTIAL MEDICAL CENTERNYEmergency Medicine Physician (207P00000X)
United
81325$768.811255478004 - CHRISTOPHER RAIO208243412 - SAMARITAN EMERGENCY MEDICAL SERVICES PCNYEmergency Medicine Physician (207P00000X)
United
81325$269.351598375651 - E AND A MEDICAL ON THE GO HEALTHCARE OF SOUTH FLORIDA LLC, E AND A HEALTHCARE ON THE GO832289173 - (FL) E AND A MEDICAL ON THE GO HEALTHCARE OF SOUTH FLORIDA LLCFLHome Health Agency (251E00000X)
United
81325$914.261255478004 - CHRISTOPHER RAIO208243412 - SAMARITAN EMERGENCY MEDICAL SERVICES PCNYEmergency Medicine Physician (207P00000X)
United
81325$1015.851255478004 - CHRISTOPHER RAIO113438973 - ST JOSEPH HOSPITALNYEmergency Medicine Physician (207P00000X)
United
81325$1028.811437126745 - ALAN MELTZER521958352 - ATLANTIC HEALTH SYSTEM INCNJPediatrics Physician (208000000X)
United
81325$769.581073502985 - CHU CHEN42484572 - MERRIMACK VALLEY PEDIATRIC ASSOCIATES, INC.MAPediatrics Physician (208000000X)
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist

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CPT 81325 vs. Other Molecular Pathology Procedures Codes

The CPT 81325 code is part of the Pathology and Laboratory Procedures services used for Molecular Pathology Procedures. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The CPT 81325 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
81292-CPTModerateMlh1 (Mutl Homolog 1, Colon Cancer, Nonpolyposis Type 2) (Eg, Hereditary Non-Polyposis Colorectal Cancer, Lynch Syndrome) Gene Analysis; Full Sequence Analysis
81305-CPTLowMyd88 (Myeloid Differentiation Primary Response 88) (Eg, Waldenstrom's Macroglobulinemia, Lymphoplasmacytic Leukemia) Gene Analysis, P.Leu265pro (L265p) Variant
81306-CPTModerateNudt15 (Nudix Hydrolase 15) (Eg Drug Metabolism) Gene Analysis Common Variant(S) (Eg *2 *3 *4 *5 *6)
81325-CPTModeratePmp22 (Peripheral Myelin Protein 22) (Eg, Charcot-Marie-Tooth, Hereditary Neuropathy With Liability To Pressure Palsies) Gene Analysis; Full Sequence Analysis

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 81325. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 81325 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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