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See a sample rate comparisonCPT 81333 Fee Schedule
Last Verified: October 2026
Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.
Corneal Dystrophy Genetic Test, A Lab Analysis Of Genetic Material That Can Indicate Corneal Dystrophy Which Affects The Clarity Of The Eye Cornea. Types Of Analysis Include Gene Variants Full Sequence Analysis Or Breakpoints.
| Key Fact | Detail |
|---|---|
| Service Type | Pathology and Laboratory Procedures Molecular Pathology Procedures |
| Common Place of Service | 81 - Independent Laboratory 11 - Office 99 - Other POS |
| Common Modifiers | None 90 - Reference Laboratory 59 - Distinct Procedural Service |
| Complexity Level | Low |
| Medicare Fee Schedule | View Medicare rates for 81333 |
| Medicaid Fee Schedule | View Medicaid rates for 81333 |
National average reimbursement for CPT 81333 by major payers:
$109.35
$83.98
$128.76
$209.87
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CPT 81333
5 of 25 sample ratesHigher to lower in this preview
Chu Chen
Merrimack Valley Pediatric Associates, Inc.
$301.40Published rateChu Chen
Merrimack Valley Pediatric Associates, Inc.
$137.00Published rateChristopher Raio
Mercy Medical Center
$82.20Published rateCabrini Sutherland
Surgical Specialists Of Charlotte, PA
$68.50Published rateBaptist Health Care, Inc., Baptist Home Healt Care And Medical Equipment
Baptist Health Care Inc
$57.54Published rate
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See a sample payer proposalCPT 81333 vs. Other Molecular Pathology Procedures Codes
The CPT 81333 code is part of the Pathology and Laboratory Procedures services used for Molecular Pathology Procedures. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.
The CPT 81333 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.
| Code | Complexity | Description |
|---|---|---|
| 81332-CPT | Low | Serpina1 (Serpin Peptidase Inh, Serpina1 (Serpin Peptidase Inhibitor Clade A Alpha-1 Antiproteinase Antitrypsin Member 1) (Eg Alpha-1-Antitrypsin Deficiency) Gene Analysis Common Variants (Eg S And Z) |
| 81333-CPT | Low | Corneal Dystrophy Genetic Test, A Lab Analysis Of Genetic Material That Can Indicate Corneal Dystrophy Which Affects The Clarity Of The Eye Cornea. Types Of Analysis Include Gene Variants Full Sequence Analysis Or Breakpoints. |
| 81334-CPT | Moderate | Runx1 (Runt Related Transcript, Runx1 (Runt Related Transcription Factor 1) (Eg Acute Myeloid Leukemia Familial Platelet Disorder With Associated Myeloid Malignancy) Gene Analysis Targeted Sequence Analysis (Eg Exons 3-8) (Eg Exon 12) Hpa-9ab (V837m) |
What is a fee schedule?
A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 81333. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.
Understanding the 81333 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.
Factors that affect fee schedules
Medicare & Medicaid Rates
Government-set reimbursement amounts
Private Insurance Rates
Negotiated rates between providers and insurance companies
Geographic Location
Costs may be higher in urban areas.
Provider Type
Hospital providers may have different rates than private practice.
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