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CPT 81340 Fee Schedule

Last Verified: November 2025

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Trb@ (T Cell Antigen Receptor, Beta) (Eg, Leukemia And Lymphoma), Gene Rearrangement Analysis To Detect Abnormal Clonal Population(S); Using Amplification Methodology (Eg, Polymerase Chain Reaction)
Key FactDetail
Service Type

Pathology and Laboratory Procedures

Molecular Pathology Procedures

Common Place of Service

81 - Independent Laboratory

22 - On Campus Outpatient Hospital

Common Modifiers

None

GZ - Item or Service Expected to Be Denied as Not Reasonable and Necessary

XE - Separate encounter

Complexity LevelLow

National average reimbursement for CPT 81340 by major payers:

bcbs

$177.22

uhc

$149.75

aetna

$213.53

cigna

$337.28

Preview provider-level rates for...
For billing codeCPT 81340
PayerCodeRateNPITax IDStateSpecialty

Select a payer to view fee schedule data

Choose a payer from the options above to see rates for CPT 81340

United
81340$119.521174078281 - DERMATOLOGY AND SKIN CANCER SURGERY CENTER, LLC, ORLANDO DERMATOLOGY CENTER208048424 - (FL) DERMATOLOGY AND SKIN CANCER SURGERY CENTER LLCFLDermatology Physician (207N00000X)
United
81340$73.121598375651 - E AND A MEDICAL ON THE GO HEALTHCARE OF SOUTH FLORIDA LLC, E AND A HEALTHCARE ON THE GO832289173 - (FL) E AND A MEDICAL ON THE GO HEALTHCARE OF SOUTH FLORIDA LLCFLHome Health Agency (251E00000X)
United
81340$125.341538620539 - DEANNA VINCENT593238640 - H LEE MOFFITT CANCER CTR & RES INST LIFE TIME CANCER SCRN CTR INCFLInternal Medicine Physician (207R00000X)
United
81340$125.341952331654 - ALBERTO CHIAPPORI593238640 - H LEE MOFFITT CANCER CTR & RES INST LIFE TIME CANCER SCRN CTR INCFLMedical Oncology Physician (207RX0202X)
United
81340$125.341174902233 - KENNETH SNELL593238640 - H LEE MOFFITT CANCER CTR & RES INST LIFE TIME CANCER SCRN CTR INCFLCritical Care Medicine (Internal Medicine) Physician (207RC0200X)
United
81340$106.551396047817 - PAMELA KUBAL593238640 - H LEE MOFFITT CANCER CTR & RES INST LIFE TIME CANCER SCRN CTR INCFLAcute Care Nurse Practitioner (363LA2100X)
United
81340$106.551295972164 - ALLISON FROMM593238640 - H LEE MOFFITT CANCER CTR & RES INST LIFE TIME CANCER SCRN CTR INCFLAdult Health Nurse Practitioner (363LA2200X)
United
81340$106.551497404032 - WEISSY ACOSTA593238640 - H LEE MOFFITT CANCER CTR & RES INST LIFE TIME CANCER SCRN CTR INCFLPhysician Assistant (363A00000X)
United
81340$106.551376046896 - AMANDA WINSLOW593238640 - H LEE MOFFITT CANCER CTR & RES INST LIFE TIME CANCER SCRN CTR INCFLCertified Registered Nurse Anesthetist (367500000X)
United
81340$106.551114258118 - RANIEL BARCENAS593238640 - H LEE MOFFITT CANCER CTR & RES INST LIFE TIME CANCER SCRN CTR INCFLAcute Care Nurse Practitioner (363LA2100X)
United
81340$125.341710177712 - ROBERT STAPP593238640 - H LEE MOFFITT CANCER CTR & RES INST LIFE TIME CANCER SCRN CTR INCFLClinical Pathology Physician (207ZC0006X)
United
81340$125.341831329655 - DAVID BUXTON593238640 - H LEE MOFFITT CANCER CTR & RES INST LIFE TIME CANCER SCRN CTR INCFLHospice and Palliative Medicine (Internal Medicine) Physician (207RH0002X)
United
81340$106.551831595016 - ASHLEY RALEY593238640 - H LEE MOFFITT CANCER CTR & RES INST LIFE TIME CANCER SCRN CTR INCFLFamily Nurse Practitioner (363LF0000X)
United
81340$125.341255913869 - DANIEL SEGARRA593238640 - H LEE MOFFITT CANCER CTR & RES INST LIFE TIME CANCER SCRN CTR INCFLInternal Medicine Physician (207R00000X)
United
81340$106.551073032504 - JULIA MOREY593238640 - H LEE MOFFITT CANCER CTR & RES INST LIFE TIME CANCER SCRN CTR INCFLAdult Health Nurse Practitioner (363LA2200X)
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist

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CPT 81340 vs. Other Molecular Pathology Procedures Codes

The CPT 81340 code is part of the Pathology and Laboratory Procedures services used for Molecular Pathology Procedures. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The CPT 81340 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
81339-CPTLowMpl (Mpl Proto-Oncogene Thrombopoietin Receptor) (Eg Myeloproliferative Disorder) Gene Analysis; Sequence Analysis Exon 10
81340-CPTLowTrb@ (T Cell Antigen Receptor, Beta) (Eg, Leukemia And Lymphoma), Gene Rearrangement Analysis To Detect Abnormal Clonal Population(S); Using Amplification Methodology (Eg, Polymerase Chain Reaction)
81341-CPTLowTrb@ (T Cell Antigen Receptor, Beta) (Eg, Leukemia And Lymphoma), Gene Rearrangement Analysis To Detect Abnormal Clonal Population(S); Using Direct Probe Methodology (Eg, Southern Blot)

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 81340. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 81340 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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