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CPT 81340 Fee Schedule

Last Verified: October 2026

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Trb Gene Rearrange Amplify, Trb T Cell Antigen Receptor Beta Eg Leukemia And Lymphoma Gene Rearrangement Analysis To Detect Abnormal Clonal Population S Using Amplification Methodology Eg Polymerase Chain Reaction
Key FactDetail
Service Type

Pathology and Laboratory Procedures

Molecular Pathology Procedures

Common Place of Service

81 - Independent Laboratory

22 - On Campus Outpatient Hospital

Common Modifiers

None

GZ - Item or Service Expected to Be Denied as Not Reasonable and Necessary

XE - Separate encounter

Complexity LevelLow
Medicare Fee ScheduleView Medicare rates for 81340
Medicaid Fee ScheduleView Medicaid rates for 81340

National average reimbursement for CPT 81340 by major payers:

bcbs

$177.22

uhc

$149.75

aetna

$213.53

cigna

$324.55

Compare published rates across providers.

Choose a payer to see a sample of rates for CPT 81340.

CPT 81340
5 of 25 sample ratesHigher to lower in this preview
  1. Overlook Hospital

    Atlantic Health System Inc

    NJGeneral Acute Care HospitalNPI 1417106907Tax ID 52-1958352

    $310.32Published rate
  2. David Schoenfeld

    H Lee Moffitt Cancer Ctr & Res Inst Life Time Cancer Scrn Ctr Inc

    FLInternal Medicine PhysicianNPI 1134757206Tax ID 59-3238640

    $125.34Published rate
  3. Heidi Heil

    H Lee Moffitt Cancer Ctr & Res Inst Life Time Cancer Scrn Ctr Inc

    FLPhysician AssistantNPI 1548286214Tax ID 59-3238640

    $106.55Published rate
  4. Lashunna Mccall

    H Lee Moffitt Cancer Ctr & Res Inst Life Time Cancer Scrn Ctr Inc

    FLFamily Nurse PractitionerNPI 1528600376Tax ID 59-3238640

    $106.55Published rate
  5. E And A Medical On The Go Healthcare Of South Florida LLC, E And A Healthcare On The Go

    E And A Medical On The Go Healthcare Of South Florida LLC

    FLHome Health AgencyNPI 1598375651Tax ID 83-2289173

    $73.12Published rate

National sample. Rates vary by location, specialty, and contract.

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CPT 81340 vs. Other Molecular Pathology Procedures Codes

The CPT 81340 code is part of the Pathology and Laboratory Procedures services used for Molecular Pathology Procedures. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The CPT 81340 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
81339-CPTLowBone Marrow Genetic Test, A Lab Analysis Of Genetic Material That Can Indicate A Problem With How Bone Marrow Creates Blood Cells. Types Of Analysis Include Gene Variants Full Sequence Analysis Or Breakpoints.
81340-CPTLowTrb Gene Rearrange Amplify, Trb T Cell Antigen Receptor Beta Eg Leukemia And Lymphoma Gene Rearrangement Analysis To Detect Abnormal Clonal Population S Using Amplification Methodology Eg Polymerase Chain Reaction
81341-CPTLowTrb Gene Rearrange Dirprobe, Trb T Cell Antigen Receptor Beta Eg Leukemia And Lymphoma Gene Rearrangement Analysis To Detect Abnormal Clonal Population S Using Direct Probe Methodology Eg Southern Blot

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 81340. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 81340 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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