Rate Benchmarking
Compare your rates with similar providers.
Select a published rate, define comparable providers, and see where that rate falls in your market.
See a sample rate comparisonCPT 81435 Fee Schedule
Last Verified: October 2026
Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.
Pathology Test, Hereditary Colon Cancer-Related Disorders (Eg Lynch Syndrome Pten Hamartoma Syndrome Cowden Syndrome Familial Adenomatosis Polyposis) Genomic Sequence Analysis Panel 5 Or More Genes Interrogation For Sequence Variants And Copy Number Variants; Genomic Sequence Analysis Panel Must Include Sequencing Of At Least 10 Genes Including Apc Bmpr1a Cdh1 Mlh1 Msh2 Msh6 Mutyh Pten Smad4 And Stk11
| Key Fact | Detail |
|---|---|
| Service Type | Pathology and Laboratory Procedures Genomic Sequencing Procedures and Other Molecular Multianalyte Assays |
| Common Place of Service | 81 - Independent Laboratory 11 - Office |
| Common Modifiers | None 90 - Reference Laboratory 59 - Distinct Procedural Service |
| Complexity Level | Moderate |
| Medicare Fee Schedule | View Medicare rates for 81435 |
| Medicaid Fee Schedule | View Medicaid rates for 81435 |
National average reimbursement for CPT 81435 by major payers:
$505.28
$420.82
$583.67
$1,012.95
Compare published rates across providers.
Choose a payer to see a sample of rates for CPT 81435.
CPT 81435
5 of 25 sample ratesHigher to lower in this preview
Christopher Raio
Mercy Medical Center
$1,347.19Published rateChristopher Raio
St Joseph Hospital
$772.07Published rateChu Chen
Merrimack Valley Pediatric Associates, Inc.
$584.90Published rateNevada Eye Care Professionals Little & Stein, Ltd.
Nevada Eye Care Professionals
$354.32Published rateAaron Askew
The Orthopedic And Neurosurgical Center Of The Cascades
$245.66Published rate
Get a free rate benchmark for your specialty.
Choose your state and specialty to build a report from payer-published rates.
Use market rates to prepare your payer proposal.
Payer Contract Negotiation
Draft a fee schedule renegotiation letter.
Use your fee schedule and market benchmarks to set target rates and draft a letter for your payer.
See a sample payer proposalCPT 81435 vs. Other Genomic Sequencing Procedures and Other Molecular Multianalyte Assays Codes
The CPT 81435 code is part of the Pathology and Laboratory Procedures services used for Genomic Sequencing Procedures and Other Molecular Multianalyte Assays. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.
The CPT 81435 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.
| Code | Complexity | Description |
|---|---|---|
| 81435-CPT | Moderate | Pathology Test, Hereditary Colon Cancer-Related Disorders (Eg Lynch Syndrome Pten Hamartoma Syndrome Cowden Syndrome Familial Adenomatosis Polyposis) Genomic Sequence Analysis Panel 5 Or More Genes Interrogation For Sequence Variants And Copy Number Variants; Genomic Sequence Analysis Panel Must Include Sequencing Of At Least 10 Genes Including Apc Bmpr1a Cdh1 Mlh1 Msh2 Msh6 Mutyh Pten Smad4 And Stk11 |
| 81437-CPT | Moderate | Pathology Panel/Obstetric, Hereditary Neuroendocrine Tumor-Related Disorders (Eg Medullary Thyroid Carcinoma Parathyroid Carcinoma Malignant Pheochromocytoma Or Paraganglioma) Genomic Sequence Analysis Panel 5 Or More Genes Interrogation For Sequence Variants And Copy Number Variants; Genomic Sequence Analysis Panel Must Include Sequencing Of At Least 6 Genes Including Max Sdhb Sdhc Sdhd Tmem127 And Vhl |
| 81441-CPT | High | Ibmfs Seq Alys Pnl 30 Genes, Inherited Bone Marrow Failure Syndromes Ibmfs Eg Fanconi Anemia Dyskeratosis Congenita Diamond Blackfan Anemia Shwachman Diamond Syndrome Gata2 Deficiency Syndrome Congenital Amegakaryocytic Thrombocytopenia Sequence Analysis Panel Must Include Sequencing Of At Least 30 Genes Including Brca2 Brip1 Dkc1 Fanca Fancb Fancc Fancd2 Fance Fancf Fancg Fanci Fancl Gata1 Gata2 Mpl Nhp2 Nop10 Palb2 Rad51c Rpl11 Rpl35a Rpl5 Rps10 Rps19 Rps24 Rps26 Rps7 Sbds Tert And Tinf2 |
| 81442-CPT | High | Noonan Spectrum Disorders, Noonan Spectrum Disorders Eg Noonan Syndrome Cardio Facio Cutaneous Syndrome Costello Syndrome Leopard Syndrome Noonan Like Syndrome Genomic Sequence Analysis Panel Must Include Sequencing Of At Least 12 Genes Including Braf Cbl Hras Kras Map2k1 Map2k2 Nras Ptpn11 Raf1 Rit1 Shoc2 And Sos1 |
What is a fee schedule?
A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 81435. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.
Understanding the 81435 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.
Factors that affect fee schedules
Medicare & Medicaid Rates
Government-set reimbursement amounts
Private Insurance Rates
Negotiated rates between providers and insurance companies
Geographic Location
Costs may be higher in urban areas.
Provider Type
Hospital providers may have different rates than private practice.
FREE SAMPLE MARKET COMPARISON
Let's review your payer contracts side-by-side with the market.
Bring your top codes (like CPT 81435) and we'll show you how you compare in 15 minutes or less.