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CPT 81443 Fee Schedule

Last Verified: August 2026

Healthcare providers use this code to document and receive reimbursement for visits that address high-level medical decision-making, often including multiple diagnoses or prescription management.

Genetic Tstg Severe Inh Cond, Genetic Testing For Severe Inherited Conditions Eg Cystic Fibrosis Ashkenazi Jewish Associated Disorders Eg Bloom Syndrome Canavan Disease Fanconi Anemia Type C Mucolipidosis Type Vi Gaucher Disease Tay Sachs Disease Beta Hemoglobinopathies Phenylketonuria Galactosemia Genomic Sequence Analysis Panel Must Include Sequencing Of At Least 15 Genes Eg Acadm Arsa Aspa Atp7b Bckdha Bckdhb Blm Cftr Dhcr7 Fancc G6pc Gaa Galt Gba Gbe1 Hbb Hexa Ikbkap Mcoln1 Pah
Key FactDetail
Service Type

Pathology and Laboratory Procedures

Genomic Sequencing Procedures and Other Molecular Multianalyte Assays

Common Place of Service

81 - Independent Laboratory

11 - Office

Common Modifiers

None

90 - Reference Laboratory

XS - Separate Structure

Complexity LevelHigh
Medicare Fee ScheduleView Medicare rates for 81443

National average reimbursement for CPT 81443 by major payers:

bcbs

$1,802.56

uhc

$1,462.29

aetna

$2,269.26

cigna

$3,369.99

Preview provider-level rates for...
For billing codeCPT 81443
PayerCodeRateNPITax IDStateSpecialty
United
81443$3672.841588098172 - PROGRESSIVE EMERGENCY PHYSICIANS PLLC463316332 - PROGRESSIVE EMERGENCY PHYSICIANS PLLCNYEmergency Medicine Physician (207P00000X)
United
81443$1028.401891774519 - LEON HOME HEALTH, LLC, LEON AT HOME261288029FLHome Health Agency (251E00000X)
United
81443$1322.221255478004 - CHRISTOPHER RAIO112050523 - ST FRANCIS HOSPITALNYEmergency Medicine Physician (207P00000X)
United
81443$1028.401730106824 - NEVADA EYE CARE PROFESSIONALS LITTLE & STEIN, LTD.880316581 - NEVADA EYE CARE PROFESSIONALSNVOphthalmology Physician (207W00000X)
United
81443$1028.401174078281 - DERMATOLOGY AND SKIN CANCER SURGERY CENTER, LLC, ORLANDO DERMATOLOGY CENTER208048424 - (FL) DERMATOLOGY AND SKIN CANCER SURGERY CENTER LLCFLDermatology Physician (207N00000X)
United
81443$1469.141255478004 - CHRISTOPHER RAIO111635088 - MERCY MEDICAL CENTERNYEmergency Medicine Physician (207P00000X)
United
81443$1805.671972501252 - BAYCARE HOME CARE, INC.593582520 - (FL) BAYCARE HOME CARE INCFLHome Health Agency (251E00000X)
United
81443$1805.671972501252 - BAYCARE HOME CARE, INC.593582520 - (FL) BAYCARE HOME CARE INCFLHome Health Agency (251E00000X)
United
81443$1028.401366428401 - AARON ASKEW911750212 - DESERT BONE & JOINT SPECIALISTS, LLPOROrthopaedic Trauma Physician (207XX0801X)
United
81443$1224.281811000177 - CHARLESTON RADIOLOGISTS PA570634747 - CHARLESTON RADIOLOGISTS, P.A.SCSingle Specialty Group (193400000X)
United
81443$2908.891255478004 - CHRISTOPHER RAIO113438973 - ST JOSEPH HOSPITALNYEmergency Medicine Physician (207P00000X)
United
81443$3273.371194797456 - DONALD HOELZEL521958352 - ATLANTIC HEALTH SYSTEM INCNJPediatrics Physician (208000000X)
United
81443$1322.221255478004 - CHRISTOPHER RAIO113438973 - ST JOSEPH HOSPITALNYEmergency Medicine Physician (207P00000X)
United
81443$1469.141255478004 - CHRISTOPHER RAIO111635088 - MERCY MEDICAL CENTERNYEmergency Medicine Physician (207P00000X)
United
81443$1028.401023438009 - MOLLY MCINTOSH593140335 - BAYCARE MEDICAL GROUP INCFLHome Health Agency (251E00000X)
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist

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CPT 81443 vs. Other Genomic Sequencing Procedures and Other Molecular Multianalyte Assays Codes

The CPT 81443 code is part of the Pathology and Laboratory Procedures services used for Genomic Sequencing Procedures and Other Molecular Multianalyte Assays. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The CPT 81443 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
81419-CPTHighEpilepsy Gen Seq Alys Panel, Epilepsy Genomic Sequence Analysis Panel Must Include Analyses For Aldh7a1 Cacna1a Cdkl5 Chd2 Gabrg2 Grin2a Kcnq2 Mecp2 Pcdh19 Polg Prrt2 Scn1a Scn1b Scn2a Scn8a Slc2a1 Slc9a6 Stxbp1 Syngap1 Tcf4 Tpp1 Tsc1 Tsc2 And Zeb2
81439-CPTModerateHereditary Cardiomyopathy (Eg Hypertrophic Cardiomyopathy Dilated Cardiomyopathy Arrhythmogenic Right Ventricular Cardiomyopathy) Genomic Sequence Analysis Panel Must Include Sequencing Of At Least 5 Cardiomyopathy-Related Genes (Eg Dsg2 Mybpc3 Myh7 Pkp2 Ttn) (Desc Revised 1/1/2018)
81440-CPTHighMitochondrial Gene, Nuclear Encoded Mitochondrial Genes Eg Neurologic Or Myopathic Phenotypes Genomic Sequence Panel Must Include Analysis Of At Least 100 Genes Including Bcs1l C10orf2 Coq2 Cox10 Dguok Mpv17 Opa1 Pdss2 Polg Polg2 Rrm2b Sco1 Sco2 Slc25a4 Sucla2 Suclg1 Taz Tk2 And Tymp
81443-CPTHighGenetic Tstg Severe Inh Cond, Genetic Testing For Severe Inherited Conditions Eg Cystic Fibrosis Ashkenazi Jewish Associated Disorders Eg Bloom Syndrome Canavan Disease Fanconi Anemia Type C Mucolipidosis Type Vi Gaucher Disease Tay Sachs Disease Beta Hemoglobinopathies Phenylketonuria Galactosemia Genomic Sequence Analysis Panel Must Include Sequencing Of At Least 15 Genes Eg Acadm Arsa Aspa Atp7b Bckdha Bckdhb Blm Cftr Dhcr7 Fancc G6pc Gaa Galt Gba Gbe1 Hbb Hexa Ikbkap Mcoln1 Pah

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 81443. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 81443 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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Frequently Asked Questions