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CPT 81457 Fee Schedule

Last Verified: January 2026

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Solid Organ Neoplasm, Genomic Sequence Analysis Panel, Interrogation For Sequence Variants; Dna Analysis, Microsatellite Instability
Key FactDetail
Service Type

Pathology and Laboratory Procedures

Genomic Sequencing Procedures and Other Molecular Multianalyte Assays

Complexity LevelModerate
Medicare Fee ScheduleView Medicare rates for 81457

National average reimbursement for CPT 81457 by major payers:

bcbs

$N/A

uhc

$N/A

aetna

$N/A

cigna

$N/A

Preview provider-level rates for...
For billing codeCPT 81457
PayerCodeRateNPITax IDStateSpecialty

Select a payer to view fee schedule data

Choose a payer from the options above to see rates for CPT 81457

United
81457$1198.981417106907 - OVERLOOK HOSPITAL521958352 - ATLANTIC HEALTH SYSTEM INCNJGeneral Acute Care Hospital (282N00000X)
United
81457$430.501497064679 - JENKINS COUNTY HOSPITAL LLC, OPTIM MEDICAL CENTER - JENKINS273100894GACritical Access Hospital (282NC0060X)
United
81457$538.111649646472 - LEIGH TAYLOR273818647GAGeneral Acute Care Hospital (282N00000X)
United
81457$6995.581588640692 - EMORY UNIVERSITY, EMORY UNIVERSITY HOSPITAL580566256 - (GA) EMORY UNIVERSITYGAGeneral Acute Care Hospital (282N00000X)
United
81457$1817.231396923710 - EMORY UNIVERSITY HOSPITAL582030692 - EMORY UNIVERSITYGAGeneral Acute Care Hospital (282N00000X)
United
81457$376.691174512115 - MICHAEL GUILLETTE271495988 - (NM) AZTEC URGENT CARE LLCCOPhysician Assistant (363A00000X)
United
81457$538.111689736282 - THE HOSPITAL AUTHORITY OF HABERSHAM COUNTY586002961GARural Acute Care Hospital (282NR1301X)
United
81457$376.691619087590 - MIGUEL ARENAS300394179 - (AZ) MIGUEL A ARENAS MD PCAZGastroenterology Physician (207RG0100X)
United
81457$807.171518912666 - STEPHENS COUNTY ANESTHESIA SERVICES,LLC300429607 - (GA) STEPHENS COUNTY ANESTHESIA SERVICESLLCGARural Acute Care Hospital (282NR1301X)
United
81457$538.111770684284 - THE HOSPITAL AUTHORITY OF MONROE COUNTY, GEORGIA, MONROE COUNTY HOSPITAL586010602 - (GA) THE HOSPITAL AUTHORITY OF MONROE COUNTY GEORGIAGACritical Access Hospital (282NC0060X)
United
81457$394.611083711691 - TY COBB HEALTHCARE SYSTEM, COBB MEMORIAL HOSPITAL580633978 - (GA) COMMUNITY SERVICES GROUP INCGARural Acute Care Hospital (282NR1301X)
United
81457$1198.981437126745 - ALAN MELTZER521958352 - ATLANTIC HEALTH SYSTEM INCNJPediatrics Physician (208000000X)
United
81457$376.691205890076 - APRIL LEUZINGER271495988 - (NM) AZTEC URGENT CARE LLCCOPhysician Assistant (363A00000X)
United
81457$376.691417157405 - EMORY HEALTHCARE901116753GAGeneral Acute Care Hospital (282N00000X)
United
81457$538.111255891958 - PIEDMONT NEWTON EKG BILLING LLC582155150 - (GA) PIEDMONT NEWTON HOSPITAL INCGAGeneral Acute Care Hospital (282N00000X)
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist

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CPT 81457 vs. Other Genomic Sequencing Procedures and Other Molecular Multianalyte Assays Codes

The CPT 81457 code is part of the Pathology and Laboratory Procedures services used for Genomic Sequencing Procedures and Other Molecular Multianalyte Assays. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The CPT 81457 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
81457-CPTModerateSolid Organ Neoplasm, Genomic Sequence Analysis Panel, Interrogation For Sequence Variants; Dna Analysis, Microsatellite Instability

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 81457. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 81457 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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