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See a sample rate comparisonCPT 81457 Fee Schedule
Last Verified: October 2026
Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.
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| Key Fact | Detail |
|---|---|
| Service Type | Pathology and Laboratory Procedures Genomic Sequencing Procedures and Other Molecular Multianalyte Assays |
| Complexity Level | Moderate |
| Medicare Fee Schedule | $896.87 national lab fee schedule rate (2026) · View Medicare rates for 81457 |
| Medicaid Fee Schedule | $791.035 median of the 8 states in the free preview · View Medicaid rates for 81457 |
National average reimbursement for CPT 81457 by major payers:
$879.40
$805.10
$205.05
$1,334.04
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CPT 81457
5 of 25 sample ratesHigher to lower in this preview
Emory University, Emory University Hospital
Emory University
$6,995.58Published rateKennestone Hospital, Inc., Wellstar Kennestone Hospital
Kennestone Hospital Inc
$896.86Published rateThe Hospital Authority Of Monroe County, Georgia, Monroe County Hospital
The Hospital Authority Of Monroe County Georgia
$538.11Published rateTy Cobb Healthcare System, Cobb Memorial Hospital
Community Services Group Inc
$394.61Published rateKristina Jimenez
Miguel A Arenas Md PC
$376.69Published rate
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See a sample payer proposalCPT 81457 vs. Other Genomic Sequencing Procedures and Other Molecular Multianalyte Assays Codes
The CPT 81457 code is part of the Pathology and Laboratory Procedures services used for Genomic Sequencing Procedures and Other Molecular Multianalyte Assays. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.
The CPT 81457 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.
| Code | Complexity | Description |
|---|---|---|
| 81457-CPT | Moderate | So Neo Gsap Dna Alys Microsatellite Instability, Solid Organ Neoplasm Genomic Sequence Analysis Panel Interrogation For Sequence Variants; Dna Analysis Microsatellite |
What is a fee schedule?
A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 81457. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.
Understanding the 81457 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.
Factors that affect fee schedules
Medicare & Medicaid Rates
Government-set reimbursement amounts
Private Insurance Rates
Negotiated rates between providers and insurance companies
Geographic Location
Costs may be higher in urban areas.
Provider Type
Hospital providers may have different rates than private practice.
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