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CPT 81503 Fee Schedule

Last Verified: December 2025

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Oncology (Ovarian), Biochemical Assays Of Five Proteins (Ca-125, Apolipoprotein A1, Beta-2 Microglobulin, Transferrin, And Pre-Albumin), Utilizing Serum, Algorithm Reported As A Risk Score
Key FactDetail
Service Type

Pathology and Laboratory Procedures

Multianalyte Assays with Algorithmic Analyses

Common Place of Service

81 - Independent Laboratory

11 - Office

Common Modifiers

None

90 - Reference Laboratory

TC - Technical component

GZ - Item or Service Expected to Be Denied as Not Reasonable and Necessary

Complexity LevelModerate

National average reimbursement for CPT 81503 by major payers:

bcbs

$662.18

uhc

$549.36

aetna

$799.41

cigna

$1,316.24

Preview provider-level rates for...
For billing codeCPT 81503
PayerCodeRateNPITax IDStateSpecialty

Select a payer to view fee schedule data

Choose a payer from the options above to see rates for CPT 81503

United
81503$313.951598375651 - E AND A MEDICAL ON THE GO HEALTHCARE OF SOUTH FLORIDA LLC, E AND A HEALTHCARE ON THE GO832289173 - (FL) E AND A MEDICAL ON THE GO HEALTHCARE OF SOUTH FLORIDA LLCFLHome Health Agency (251E00000X)
United
81503$661.471821097627 - BAYCARE HOME CARE, INC.593582520 - (FL) BAYCARE HOME CARE INCFLHome Health Agency (251E00000X)
United
81503$376.731447317110 - BAPTIST HEALTH CARE, INC., BAPTIST HOME HEALT CARE AND MEDICAL EQUIPMENT590657322 - BAPTIST HEALTH CARE INCFLHome Health Agency (251E00000X)
United
81503$661.471033117007 - BAYCARE HOME CARE, INC.593582520 - (FL) BAYCARE HOME CARE INCFLHome Health Agency (251E00000X)
United
81503$661.471821081720 - BAYCARE HOME CARE, INC.593582520 - (FL) BAYCARE HOME CARE INCFLHome Health Agency (251E00000X)
United
81503$661.471851390637 - BAYCARE HOME CARE, INC.593582520 - (FL) BAYCARE HOME CARE INCFLHome Health Agency (251E00000X)
United
81503$661.471972501252 - BAYCARE HOME CARE, INC.593582520 - (FL) BAYCARE HOME CARE INCFLHome Health Agency (251E00000X)
United
81503$358.791366400376 - SUNRISE HOME HEALTH CARE INC.650307774 - (FL) SUNRISE HOME HEALTH CARE INCFLHome Health Agency (251E00000X)
United
81503$661.471033117007 - BAYCARE HOME CARE, INC.593582520 - (FL) BAYCARE HOME CARE INCFLHome Health Agency (251E00000X)
United
81503$661.471952309171 - BAYCARE HOME CARE, INC.593582520 - (FL) BAYCARE HOME CARE INCFLHome Health Agency (251E00000X)
United
81503$661.471013915149 - BAYCARE HOME CARE, INC., DBA SARASOTA MEMORIAL HOME CARE593582520 - (FL) BAYCARE HOME CARE INCFLHome Health Agency (251E00000X)
United
81503$661.471720087513 - BAYCARE HOME CARE, INC.593582520 - (FL) BAYCARE HOME CARE INCFLHome Health Agency (251E00000X)
United
81503$358.791366400376 - SUNRISE HOME HEALTH CARE INC.650307774 - (FL) SUNRISE HOME HEALTH CARE INCFLHome Health Agency (251E00000X)
United
81503$661.471821097627 - BAYCARE HOME CARE, INC.593582520 - (FL) BAYCARE HOME CARE INCFLHome Health Agency (251E00000X)
United
81503$897.001073502985 - CHU CHEN42484572 - MERRIMACK VALLEY PEDIATRIC ASSOCIATES, INC.MAPediatrics Physician (208000000X)
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist

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CPT 81503 vs. Other Multianalyte Assays with Algorithmic Analyses Codes

The CPT 81503 code is part of the Pathology and Laboratory Procedures services used for Multianalyte Assays with Algorithmic Analyses. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The CPT 81503 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
81500-CPTModerateOncology (Ovarian) Biochemical Assays Of Two Proteins (Ca-125 And He4) Utilizing Serum With Menopausal Status Algorithm Reported As A Risk Score
81503-CPTModerateOncology (Ovarian), Biochemical Assays Of Five Proteins (Ca-125, Apolipoprotein A1, Beta-2 Microglobulin, Transferrin, And Pre-Albumin), Utilizing Serum, Algorithm Reported As A Risk Score
81504-CPTModerateOncology (Tissue Of Origin) Microarray Gene Expression Profiling Of > 2000 Genes Utilizing Formalin-Fixed Paraffin Embedded Tissue Algorithm Reported As Tissue Similarity Scores.
81506-CPTLowEndocrinology (Type 2 Diabetes), Biochemical Assays Of Seven Analytes (Glucose, Hba1c, Insulin, Hs-Crp, Adiponectin, Ferritin, Interleukin 2-Receptor Alpha), Utilizing Serum Or Plasma, Algorithm Reporting A Risk Score

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 81503. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 81503 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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