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CPT 81518 Fee Schedule

Last Verified: September 2026

Healthcare providers use this code to document and receive reimbursement for visits that address high-level medical decision-making, often including multiple diagnoses or prescription management.

Onc Brst Mrna 11 Genes, Oncology Breast Mrna Gene Expression Profiling By Real Time Rt Pcr Of 11 Genes 7 Content And 4 Housekeeping Utilizing Formalin Fixed Paraffin Embedded Tissue Algorithms Reported As Percentage Risk For Metastatic Recurrence And Likelihood Of Benefit From Extended Endocrine Therapy
Key FactDetail
Service Type

Pathology and Laboratory Procedures

Multianalyte Assays with Algorithmic Analyses

Common Place of Service

81 - Independent Laboratory

11 - Office

Common Modifiers

None

90 - Reference Laboratory

59 - Distinct Procedural Service

Complexity LevelHigh
Medicare Fee ScheduleView Medicare rates for 81518
Medicaid Fee ScheduleView Medicaid rates for 81518

National average reimbursement for CPT 81518 by major payers:

bcbs

$2,924.66

uhc

$2,364.59

aetna

$3,514.63

cigna

$5,314.51

Compare published rates across providers.

Choose a payer to see a sample of rates for CPT 81518.

CPT 81518
5 of 25 sample ratesHigher to lower in this preview
  1. Chu Chen

    Merrimack Valley Pediatric Associates, Inc.

    MAPediatrics PhysicianNPI 1073502985Tax ID 42-484572

    $8,520.60Published rate
  2. Aaron Askew

    Praxis Health, P.C.

    OROrthopaedic Trauma PhysicianNPI 1366428401Tax ID 93-1224010

    $4,260.30Published rate
  3. Baycare Home Care, Inc.

    Baycare Home Care Inc

    FLHome Health AgencyNPI 1134127301Tax ID 59-3582520

    $2,856.11Published rate
  4. Matthew Lilley

    The Orthopedic And Neurosurgical Center Of The Cascades

    OROrthopaedic Surgery PhysicianNPI 1003166612Tax ID 93-1261079

    $1,626.66Published rate
  5. E And A Medical On The Go Healthcare Of South Florida LLC, E And A Healthcare On The Go

    E And A Medical On The Go Healthcare Of South Florida LLC

    FLHome Health AgencyNPI 1598375651Tax ID 83-2289173

    $1,355.55Published rate

National sample. Rates vary by location, specialty, and contract.

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CPT 81518 vs. Other Multianalyte Assays with Algorithmic Analyses Codes

The CPT 81518 code is part of the Pathology and Laboratory Procedures services used for Multianalyte Assays with Algorithmic Analyses. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The CPT 81518 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
81518-CPTHigh
Onc Brst Mrna 11 Genes, Oncology Breast Mrna Gene Expression Profiling By Real Time Rt Pcr Of 11 Genes 7 Content And 4 Housekeeping Utilizing Formalin Fixed Paraffin Embedded Tissue Algorithms Reported As Percentage Risk For Metastatic Recurrence And Likelihood Of Benefit From Extended Endocrine Therapy
81519-CPTHigh
Oncology (Breast) Mrna Gene, Oncology (Breast) Mrna Gene Expression Profilingby Real-Time Rt-Pcr Of 21 Genes Utilizing Formal In-Fixed Paraffin-Embedded Tissue Algorithm Reported As Recurrence Score
81520-CPTHigh
Oncology (Breast) Mrna Gene E, Oncology (Breast) Mrna Gene Expression Profiling By Hybrid Capture Of 58 Genes (50 Content And 8 Housekeeping) Utilizing Formalin-Fixed Paraffin-Embedded Tissue Algorithm Reported As A Recurrence Risk Score Hpa-9ab (V837m)
81521-CPTHigh
Oncology (Breast) Mrna Micro, Oncology (Breast) Mrna Microarray Gene Expression Profiling Of 70 Content Genes And 465 Housekeeping Genes Utilizing Fresh Frozen Or Formalin-Fixedparaffin-Embedded Tissue Algorithm Reported As I Ndex Related To Risk Of Distant Metastasis Hpa-9ab (V837m)

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 81518. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 81518 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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