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See a sample rate comparisonHealthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.
| Key Fact | Detail |
|---|---|
| Service Type | Pathology and Laboratory Procedures Chemistry Procedures |
| Common Place of Service | 81 - Independent Laboratory 11 - Office |
| Common Modifiers | 90 - Reference Laboratory 26 - Professional component |
| Complexity Level | Low |
| Medicare Fee Schedule | $22.97 national lab fee schedule rate (2026) · View Medicare rates for 82653 |
| Medicaid Fee Schedule | $22.455 median of the 8 states in the free preview · View Medicaid rates for 82653 |
National average reimbursement for CPT 82653 by major payers:

$18.17

$13.92

$24.30

$59.21
Choose a payer to see a sample of rates for CPT 82653.
Chu Chen
Merrimack Valley Pediatric Associates, Inc.
Chu Chen
Merrimack Valley Pediatric Associates, Inc.
Catherine Lee
Columbus Arthritis Center
Bradley Weisner
Urology Specialists Of The Carolinas, PLLC
Sunrise Home Health Care Inc.
Sunrise Home Health Care Inc
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Rate Benchmarking
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See a sample payer proposalCPT 82653 vs. Other Chemistry Procedures Codes
The CPT 82653 code is part of the Pathology and Laboratory Procedures services used for Chemistry Procedures. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.
The CPT 82653 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.
| Code | Complexity | Description |
|---|---|---|
| 82482-CPT | Low | Liver Function Blood Test, The Cholinesterase Blood Test Can Indicate Damage To The Liver Or Exposure To Pesticides If Amounts Are Low. Cholinesterase Is An Enzyme Produced In The Liver. |
| 82485-CPT | Low | Test For Dermatan Sulfate, Dermatan Sulfate (Chondroitin B Sulfate) Is Found In The Skin Blood Vessels And Valves Tendons And Lungs. It Belongs To A Group Of Substances That Play An Important Role In Carbohydrate Digestion. The Test Indicates Whether Amounts Are Out Of Balance. |
| 82607-CPT | Low | Test Of Vitamin B12 Deficiency, This Blood Test Checks For Deficiencies Of Vitamin B12 Which Plays An Important Role In Digestion Healthy Nerves And Growth Of Red Blood Cells. |
| 82653-CPT | Low | Lab Test For Antibody Levels, This Lab Test Measures A Component Of Antibody Proteins In The Blood. |
What is a fee schedule?
A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 82653. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.
Understanding the 82653 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.
Factors that affect fee schedules
Medicare & Medicaid Rates
Government-set reimbursement amounts
Private Insurance Rates
Negotiated rates between providers and insurance companies
Geographic Location
Costs may be higher in urban areas.
Provider Type
Hospital providers may have different rates than private practice.
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