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See a sample rate comparisonHealthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.
| Key Fact | Detail |
|---|---|
| Service Type | Pathology and Laboratory Procedures Chemistry Procedures |
| Common Place of Service | 81 - Independent Laboratory 11 - Office |
| Common Modifiers | 90 - Reference Laboratory 26 - Professional component |
| Complexity Level | Low |
| Medicare Fee Schedule | $18.00 national lab fee schedule rate (2026) · View Medicare rates for 84449 |
| Medicaid Fee Schedule | $17.775 median of the 8 states in the free preview · View Medicaid rates for 84449 |
National average reimbursement for CPT 84449 by major payers:

$15.58

$21.32

$19.64

$26.20
Choose a payer to see a sample of rates for CPT 84449.
Restorative Health Rehabilitation Inc
Christopher Raio
Samaritan Emergency Medical Services PC
Prisma Health-Upstate, Prisma Health Cancer Inst-Faris
Prisma Health - Upstate
Baycare Home Care, Inc.
Baycare Home Care Inc
E And A Medical On The Go Healthcare Of South Florida LLC, E And A Healthcare On The Go
E And A Medical On The Go Healthcare Of South Florida LLC
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Rate Benchmarking
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See a sample payer proposalCPT 84449 vs. Other Chemistry Procedures Codes
The CPT 84449 code is part of the Pathology and Laboratory Procedures services used for Chemistry Procedures. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.
The CPT 84449 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.
| Code | Complexity | Description |
|---|---|---|
| 84228-CPT | Low | Malaria Medication Monitoring, Quinine Is An Antimalarial Drug That Can Cause Severe Side Effects. Its Use Is Monitored To Ensure The Lowest Possible Therapeutic Dose As Well As To Check For Toxicity. |
| 84449-CPT | Low | Cortisol Binding Protein Test, Cortisol Binding Protein Is A Measure Of Adrenal Gland Function. It Also Plays A Role In Metabolism Of Fats And Water. The Test Is Used To Evaluate Or Identify A Variety Of Conditions. |
| 84450-CPT | Low | Enzyme (Ast) Blood Test, Ast (Aspartate Aminotransferase) Is An Enzyme That Transforms Amino Acids To Energy For Cells. The Test Result Is Often Used To Assess Liver Or Heart Damage. |
| 84460-CPT | Low | Liver Enzyme (Alt) Test, This Test Measures Alanine Aminotransferase (Alt) An Enzyme Made In The Liver That Transforms Amino Acids To Energy For Cells. The Test Helps To Evaluate Liver Disease. |
What is a fee schedule?
A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 84449. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.
Understanding the 84449 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.
Factors that affect fee schedules
Medicare & Medicaid Rates
Government-set reimbursement amounts
Private Insurance Rates
Negotiated rates between providers and insurance companies
Geographic Location
Costs may be higher in urban areas.
Provider Type
Hospital providers may have different rates than private practice.
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