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CPT 86381 Fee Schedule

Last Verified: December 2025

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Mitochondrial Antibody (E.G., M2), Each
Key FactDetail
Service Type

Pathology and Laboratory Procedures

Immunology Procedures

Common Place of Service

81 - Independent Laboratory

11 - Office

Common Modifiers

None

90 - Reference Laboratory

26 - Professional component

Complexity LevelLow

National average reimbursement for CPT 86381 by major payers:

bcbs

$21.38

uhc

$15.68

aetna

$24.48

cigna

$67.32

Preview provider-level rates for...
For billing codeCPT 86381
PayerCodeRateNPITax IDStateSpecialty

Select a payer to view fee schedule data

Choose a payer from the options above to see rates for CPT 86381

United
86381$10.681295182913 - KEVIN HANCOCK593366100 - NORTH FLORIDA SURGEONS, P.A.FLColon & Rectal Surgery Physician (208C00000X)
United
86381$15.271285078436 - JEREMY JOHN593214635 - FLORIDA HOSPITAL MEDICAL GROUP INCFLSurgery Physician (208600000X)
United
86381$10.681649472069 - ALFONSO CASTRO593140335 - BAYCARE MEDICAL GROUP INCFLPulmonary Disease Physician (207RP1001X)
United
86381$15.271649212879 - ANTHONY DEIORIO462021581 - FLORIDA HOSPITAL PHYSICIAN GROUP INCFLSurgery Physician (208600000X)
United
86381$10.681447242805 - GERARD CURTIS853070134 - (FL) ADVANCED UROLOGY OF SARASOTA LLCFLUrology Physician (208800000X)
United
86381$38.561538131719 - ROBERT COHEN133957095 - (NY) THE NEW YORK AND PRESBYTERIAN HOSPITALFLDermatology Physician (207N00000X)
United
86381$10.681093896367 - DAVID LUSTIG593569143 - (FL) CENTRAL FLORIDA CANCER INSTITUTE PAFLUrology Physician (208800000X)
United
86381$8.901104239946 - MICHAEL RENDA352285106FLSurgery Physician (208600000X)
United
86381$8.901245685908 - PATRICK TENBRINK263187119 - (FL) JUPITER MEDICAL CENTER PHYSICIANS GROUP INCFLUrology Physician (208800000X)
United
86381$10.681144541152 - MATTHEW SMITH593366100 - NORTH FLORIDA SURGEONS, P.A.FLSurgery Physician (208600000X)
United
86381$10.681417956046 - RICK SCHMIDT593140335 - BAYCARE MEDICAL GROUP INCFLSurgery Physician (208600000X)
United
86381$10.681659473940 - ERIC DINER593140335 - BAYCARE MEDICAL GROUP INCFLUrology Physician (208800000X)
United
86381$8.901245743251 - RALPH M ZAGHA MD PA204880079 - (FL) RALPH M ZAGHA MD PAFLUrology Physician (208800000X)
United
86381$10.681154358109 - GANESH AKULA593132500 - (FL) ORLANDO PULMONARY AND CRITICAL CARE ASSOCIATES INCFLPulmonary Disease Physician (207RP1001X)
United
86381$10.681134389364 - NEIL SANDHU474682949 - (FL) NEIL SANDHU PAFLDermatology Physician (207N00000X)
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist

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CPT 86381 vs. Other Immunology Procedures Codes

The CPT 86381 code is part of the Pathology and Laboratory Procedures services used for Immunology Procedures. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The CPT 86381 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
86376-CPTLowMicrosomal Antibody (Thyroid);Ria
86381-CPTLowMitochondrial Antibody (E.G., M2), Each
86382-CPTLowNeutralization Test,Viral
86384-CPTLowNitroblue Tetrazolium Dye Test (Ntd)

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 86381. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 86381 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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