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CPT 87451 Fee Schedule

Last Verified: October 2026

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Infectious Agent Antigen Detection By Immunoassay Technique (Eg Enzyme Immunoassay [Eia] Enzyme- Linked Immunosorbent Assay [Elisa] Fluorescence Immunoassay [Fia] Immuno- Chemiluminometric Assay [Imca]) Qualitative Or Semiquantitative; Polyvalent For Multiple Organisms Each Polyvalent Antiserum (Desc Rvsd 10/6/20)
Key FactDetail
Service Type

Pathology and Laboratory Procedures

Microbiology Procedures

Common Place of Service

81 - Independent Laboratory

20 - Urgent Care Facility

Common Modifiers

None

59 - Distinct Procedural Service

26 - Professional component

Complexity LevelLow
Medicare Fee ScheduleView Medicare rates for 87451
Medicaid Fee ScheduleView Medicaid rates for 87451

National average reimbursement for CPT 87451 by major payers:

bcbs

$9.39

uhc

$7.21

aetna

$11.12

cigna

$15.44

Compare published rates across providers.

Choose a payer to see a sample of rates for CPT 87451.

CPT 87451
5 of 25 sample ratesHigher to lower in this preview
  1. Restorative Health Rehabilitation Inc

    FLHome Health AgencyNPI 1649599168Tax ID 27-2533824

    $60.00Published rate
  2. Christopher Raio

    Mercy Medical Center

    NYEmergency Medicine PhysicianNPI 1255478004Tax ID 11-1635088

    $11.07Published rate
  3. Prisma Health-Upstate, Prisma Health Cancer Inst-Greer

    Prisma Health - Upstate

    SCGeneral Acute Care HospitalNPI 1841746948Tax ID 81-1723202

    $9.46Published rate
  4. Christopher Raio

    Samaritan Emergency Medical Services PC

    NYEmergency Medicine PhysicianNPI 1255478004Tax ID 20-8243412

    $6.31Published rate
  5. E And A Medical On The Go Healthcare Of South Florida LLC, E And A Healthcare On The Go

    E And A Medical On The Go Healthcare Of South Florida LLC

    FLHome Health AgencyNPI 1598375651Tax ID 83-2289173

    $3.68Published rate

National sample. Rates vary by location, specialty, and contract.

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CPT 87451 vs. Other Microbiology Procedures Codes

The CPT 87451 code is part of the Pathology and Laboratory Procedures services used for Microbiology Procedures. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The CPT 87451 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
87430-CPTLowInfectious Agent Antigen Detection By Immunoassay Technique (Eg Enzyme Immunoassay [Eia] Enzyme- Linked Immunosorbent Assay [Elisa] Fluorescence Immunoassay [Fia] Immuno- Chemiluminometric Assay [Imca]) Qualitative Or Semiquantitative; Streptococcus Group A (Desc Rvsd 10/6/20)
87449-CPTLowInfectious Agent Antigen Detection By Immunoassa Technique (Eg Enzyme Immunoassay [Eia] Enzyme Linked Immunosorbent Assay [Elisa] Fluorescence Immunoassay [Fia] Immuno- Chemiluminometric Assay [Imca]) Qualitative Or Semiquantitative; Not Otherwise Specified Each Organism (Desc Rvsd 10/6/20)
87451-CPTLowInfectious Agent Antigen Detection By Immunoassay Technique (Eg Enzyme Immunoassay [Eia] Enzyme- Linked Immunosorbent Assay [Elisa] Fluorescence Immunoassay [Fia] Immuno- Chemiluminometric Assay [Imca]) Qualitative Or Semiquantitative; Polyvalent For Multiple Organisms Each Polyvalent Antiserum (Desc Rvsd 10/6/20)
87467-CPTLowHepatitis B Surface Ag Quan, Infectious Agent Antigen Detection By Immunoassay Technique Eg Enzyme Immunoassay Eia Enzyme Linked Immunosorbent Assay Elisa Fluorescence Immunoassay Fia Immunochemiluminometric Assay Imca Qualitative Or Semiquantitative Hepatitis B Surface Antigen Hbsag Quantitative

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 87451. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 87451 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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