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CPT 87581 Fee Schedule

Last Verified: September 2026

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Infect Agnt Detect By Nucleic Acid (Dna Or Rna); Mycoplasma Pn, Infectious Agent Detection By Nucleic Acid (Dna Or Rna); Mycoplasma Pn
Key FactDetail
Service Type

Pathology and Laboratory Procedures

Microbiology Procedures

Common Place of Service

81 - Independent Laboratory

11 - Office

Common Modifiers

None

59 - Distinct Procedural Service

26 - Professional component

Complexity LevelLow
Medicare Fee ScheduleView Medicare rates for 87581
Medicaid Fee ScheduleView Medicaid rates for 87581

National average reimbursement for CPT 87581 by major payers:

bcbs

$32.70

uhc

$25.23

aetna

$37.49

cigna

$50.89

Compare published rates across providers.

Choose a payer to see a sample of rates for CPT 87581.

CPT 87581
5 of 25 sample ratesHigher to lower in this preview
  1. Chu Chen

    Merrimack Valley Pediatric Associates, Inc.

    MAPediatrics PhysicianNPI 1073502985Tax ID 42-484572

    $77.20Published rate
  2. Restorative Health Rehabilitation Inc

    FLHome Health AgencyNPI 1649599168Tax ID 27-2533824

    $40.00Published rate
  3. Prisma Health-Upstate, Prisma Health Cancer Inst-Easley

    Prisma Health - Upstate

    SCGeneral Acute Care HospitalNPI 1851847974Tax ID 81-1723202

    $31.57Published rate
  4. Nicole Schwab

    Allergy & Asthma Of Dupage, S.C.

    ILFamily Nurse PractitionerNPI 1164776688Tax ID 36-2925195

    $28.07Published rate
  5. Bsa Hospital LLC

    TXGeneral Acute Care HospitalNPI 1407191984Tax ID 30-0754305

    $14.73Published rate

National sample. Rates vary by location, specialty, and contract.

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CPT 87581 vs. Other Microbiology Procedures Codes

The CPT 87581 code is part of the Pathology and Laboratory Procedures services used for Microbiology Procedures. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The CPT 87581 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
87534-CPTLowInfectious Agent Detection By, Infectious Agent Detection By Nucleic Acid (Dna Orrna)Hiv-1 Direct Probe Technique Infectious Ag Ent Detection By Nucleic Acid (Dna Or Rna)
87580-CPTLowInfectious Agent Detection By, Infectious Agent Detection By Nucleic Acid (Dna Orrna)Mycoplasma Pneumoniae Direct Probe Techniqu E Infectious Agent Detection By Nucleic Acid (Dnaor Rna)
87581-CPTLowInfect Agnt Detect By Nucleic Acid (Dna Or Rna); Mycoplasma Pn, Infectious Agent Detection By Nucleic Acid (Dna Or Rna); Mycoplasma Pn
87582-CPTModerateInfectious Agent Detection By, Infectious Agent Detection By Nucleic Acid (Dna Orrna)Mycoplasma Pneumoniae Quantification Infec Tious Agent Detection By Nucleic Acid (Dna Or Rna)

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 87581. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 87581 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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