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See a sample rate comparisonCPT 88161 is classified under Pathology and Laboratory Procedures, in the Cytopathology Procedures subgroup.
| Key Fact | Detail |
|---|---|
| Service Type | Pathology and Laboratory Procedures Cytopathology Procedures |
| Common Place of Service | 11 - Office 22 - On Campus Outpatient Hospital |
| Common Modifiers | XU - Unusual Non-Overlapping Service 26 - Professional component |
| Complexity Level | Low |
| Medicare Fee Schedule | $82.83 national non-facility rate (2026) · View Medicare rates for 88161 |
| Medicaid Fee Schedule | $68.50 median of the 8 states in the free preview · View Medicaid rates for 88161 |
National average reimbursement for CPT 88161 by major payers:

$84.25
BCBS / Anthem

$53.99
UnitedHealthcare

$70.53
Aetna

$74.56
Cigna
Choose a payer to see a sample of rates for CPT 88161.
Ahmad Tarhini
H Lee Moffitt Cancer Ctr & Res Inst Life Time Cancer Scrn Ctr Inc
Nancy Gardner
H Lee Moffitt Cancer Ctr & Res Inst Life Time Cancer Scrn Ctr Inc
Mayrin Correa Medina
H Lee Moffitt Cancer Ctr & Res Inst Life Time Cancer Scrn Ctr Inc
Bijal Shah
H Lee Moffitt Cancer Ctr & Res Inst Life Time Cancer Scrn Ctr Inc
Stephanee Smikker
H Lee Moffitt Cancer Ctr & Res Inst Life Time Cancer Scrn Ctr Inc
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Rate Benchmarking
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See a sample rate comparisonPayer Contract Negotiation
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See a sample payer proposalCPT 88161 vs. Other Cytopathology Procedures Codes
The table lists codes related to 88161. Select one to see its fee schedule.
| Code | Complexity | Description |
|---|---|---|
| 88160-CPT | Low | Lab Analysis Of Cell Sample, Cell Study To Determine Existence Cause Or Progression Of A Disease. Cells Are Smeared Onto A Slide Or Other Medium And Examined Microscopically. Stains May Be Used To Highlight Features. |
| 88161-CPT | Low | Lab Analysis Of Cell Sample, Cell Study To Determine Existence Cause Or Progression Of A Disease. Cells Are Smeared Onto A Slide Or Other Medium And Examined Microscopically. Stains May Be Used To Highlight Features. |
| 88162-CPT | Low | Lab Analysis Of Cell Sample, Cell Study To Determine Existence Cause Or Progression Of A Disease. Cells Are Smeared Onto A Slide Or Other Medium And Examined Microscopically. Stains May Be Used To Highlight Features. |
| 88164-CPT | Low | Pap Test, A Pap Test (Or Pap Smear) Is A Procedure Where Cells Are Collected From The Cervix (Uterus) Or Vagina To Test For Cancer Or Pre-Cancerous Cells And Done Under Physician Supervision. |
What is a fee schedule?
A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 88161. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.
Understanding the 88161 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.
Factors that affect fee schedules
Medicare & Medicaid Rates
Government-set reimbursement amounts
Private Insurance Rates
Negotiated rates between providers and insurance companies
Geographic Location
Costs may be higher in urban areas.
Provider Type
Hospital providers may have different rates than private practice.
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