Rate Benchmarking
Compare your rates with similar providers.
Select a published rate, define comparable providers, and see where that rate falls in your market.
See a sample rate comparisonCPT 88280 Fee Schedule
Last Verified: October 2026
Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.
Additional Genetic Study, Additional Studies Of Full Chromosome Sets That Describes A Persons Genetic Makeup (Karyotypes) Beyond The Base Chromosome Analysis. Karyotypes Help To Identify And Organize Genetic Abnormalities And Can Pinpoint Diagnosis Of Certain Cancers.
| Key Fact | Detail |
|---|---|
| Service Type | Pathology and Laboratory Procedures Cytogenetic Studies |
| Common Place of Service | 81 - Independent Laboratory 11 - Office |
| Common Modifiers | PO - Services, procedures and/or surgeries furnished at off-campus provider-based outpatient departments 90 - Reference Laboratory |
| Complexity Level | Low |
| Medicare Fee Schedule | $33.47 national lab fee schedule rate (2026) · View Medicare rates for 88280 |
| Medicaid Fee Schedule | $33.05 median of the 8 states in the free preview · View Medicaid rates for 88280 |
National average reimbursement for CPT 88280 by major payers:
$30.60
$28.13
$34.29
$48.14
Compare published rates across providers.
Choose a payer to see a sample of rates for CPT 88280.
CPT 88280
5 of 25 sample ratesHigher to lower in this preview
Chu Chen
Merrimack Valley Pediatric Associates, Inc.
$80.80Published rateChristopher Raio
St Francis Hospital
$33.47Published ratePrisma Health-Upstate, Prisma Health Cancer Inst-Grove
Prisma Health - Upstate
$30.12Published rateAaron Askew
Desert Bone & Joint Specialists, LLP
$20.51Published rateChristopher Raio
Mercy Medical Center
$13.77Published rate
Get a free rate benchmark for your specialty.
Choose your state and specialty to build a report from payer-published rates.
Use market rates to prepare your payer proposal.
Payer Contract Negotiation
Draft a fee schedule renegotiation letter.
Use your fee schedule and market benchmarks to set target rates and draft a letter for your payer.
See a sample payer proposalCPT 88280 vs. Other Cytogenetic Studies Codes
The CPT 88280 code is part of the Pathology and Laboratory Procedures services used for Cytogenetic Studies. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.
The CPT 88280 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.
| Code | Complexity | Description |
|---|---|---|
| 88272-CPT | Low | Chromosome Genetic Study, The Test Uses A Fluorescent Stain To Detect Dna Sequence In Cells. Dna Sequence Determines An Individuals Genetic Makeup. |
| 88273-CPT | Low | Molecular Cytogenetics Chromo, Molecular Cytogenetics Chromosomal In Situ Hybridizationanalyze 10-30 Cells (Eg For Microdeletions) Molecular Cytogenetics Chromosomal In Situ Hybridization |
| 88274-CPT | Low | Genetic Analysis Of Cells, This Study Uses A Technique That Separates And Recombines A Dna Strand Directly On A Viewing Slide. The Technique Analyzes How A Genetic Alteration Affects The Number Of Genes In A Specified Number Of Cells. |
| 88280-CPT | Low | Additional Genetic Study, Additional Studies Of Full Chromosome Sets That Describes A Persons Genetic Makeup (Karyotypes) Beyond The Base Chromosome Analysis. Karyotypes Help To Identify And Organize Genetic Abnormalities And Can Pinpoint Diagnosis Of Certain Cancers. |
What is a fee schedule?
A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 88280. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.
Understanding the 88280 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.
Factors that affect fee schedules
Medicare & Medicaid Rates
Government-set reimbursement amounts
Private Insurance Rates
Negotiated rates between providers and insurance companies
Geographic Location
Costs may be higher in urban areas.
Provider Type
Hospital providers may have different rates than private practice.
FREE SAMPLE MARKET COMPARISON
Let's review your payer contracts side-by-side with the market.
Bring your top codes (like CPT 88280) and we'll show you how you compare in 15 minutes or less.