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CPT 88319 Fee Schedule

Last Verified: July 2026

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Identify Enzyme In Tissue, The Test Involves Staining A Tissue Sample. If A Suspected Enzyme Is Present It Will Turn A Color Different From The Surrounding Tissue.
Key FactDetail
Service Type

Surgical Pathology Procedures

Pathology and Laboratory Procedures

Common Place of Service

22 - On Campus Outpatient Hospital

21 - Inpatient Hospital

Common Modifiers

None

26 - Professional component

59 - Distinct Procedural Service

Complexity LevelLow
Medicare Fee ScheduleView Medicare rates for 88319

National average reimbursement for CPT 88319 by major payers:

bcbs

$151.55

uhc

$97.26

aetna

$138.14

cigna

$135.14

Preview provider-level rates for...
For billing codeCPT 88319
PayerCodeRateNPITax IDStateSpecialty
United
88319$18.821255478004 - CHRISTOPHER RAIO113438973 - ST JOSEPH HOSPITALNYEmergency Medicine Physician (207P00000X)
United
88319$104.271255478004 - CHRISTOPHER RAIO112050523 - ST FRANCIS HOSPITALNYEmergency Medicine Physician (207P00000X)
United
88319$195.311255478004 - CHRISTOPHER RAIO112050523 - ST FRANCIS HOSPITALNYEmergency Medicine Physician (207P00000X)
United
88319$107.201235122029 - BAYCARE HOME CARE, INC.593582520 - (FL) BAYCARE HOME CARE INCFLHome Health Agency (251E00000X)
United
88319$34.091952309171 - BAYCARE HOME CARE, INC.593582520 - (FL) BAYCARE HOME CARE INCFLHome Health Agency (251E00000X)
United
88319$107.201295728186 - BAYCARE HOME CARE, INC.593582520 - (FL) BAYCARE HOME CARE INCFLHome Health Agency (251E00000X)
United
88319$55.001588756076 - ALL WAYS HOMECARE INC202696236FLHome Health Agency (251E00000X)
United
88319$40.651255478004 - CHRISTOPHER RAIO112050523 - ST FRANCIS HOSPITALNYEmergency Medicine Physician (207P00000X)
United
88319$40.651255478004 - CHRISTOPHER RAIO113438973 - ST JOSEPH HOSPITALNYEmergency Medicine Physician (207P00000X)
United
88319$42.531255478004 - CHRISTOPHER RAIO112050523 - ST FRANCIS HOSPITALNYEmergency Medicine Physician (207P00000X)
United
88319$55.001649599168 - RESTORATIVE HEALTH REHABILITATION INC272533824 - (FL) RESTORATIVE HEALTH REHABILITATION INCFLHome Health Agency (251E00000X)
United
88319$175.781255478004 - CHRISTOPHER RAIO208243412 - SAMARITAN EMERGENCY MEDICAL SERVICES PCNYEmergency Medicine Physician (207P00000X)
United
88319$40.651255478004 - CHRISTOPHER RAIO112050523 - ST FRANCIS HOSPITALNYEmergency Medicine Physician (207P00000X)
United
88319$44.721255478004 - CHRISTOPHER RAIO111635088 - MERCY MEDICAL CENTERNYEmergency Medicine Physician (207P00000X)
United
88319$51.681598375651 - E AND A MEDICAL ON THE GO HEALTHCARE OF SOUTH FLORIDA LLC, E AND A HEALTHCARE ON THE GO832289173 - (FL) E AND A MEDICAL ON THE GO HEALTHCARE OF SOUTH FLORIDA LLCFLHome Health Agency (251E00000X)
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist

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CPT 88319 vs. Other Pathology and Laboratory Procedures Codes

The CPT 88319 code is part of the Surgical Pathology Procedures services used for Pathology and Laboratory Procedures. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The CPT 88319 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
88285-CPTLowAdditional Cell Count In Study, Additional Cells Counted Beyond The Base Chromosome Analysis. The Study Uses Traditional Microscopic Techniques To Check For Genetic Anomalies And Recessive Traits. Additional Cell Counts May Be Necessary To Pinpoint A Diagnosis For Certain Cancers.
88289-CPTLowStudy For Inherited Condition, The Study Analyzes Chromosomes To Find Out If They Contain Any Genetic Traits Associated With Inherited Conditions. The Study Involves Several High-Resolution Examinations.
88291-CPTLowCytogentic & Molecular Cytogentic Interpret & Rport, Cytogenetics And Molecular Cytogenetics Interpretation And Report
88319-CPTLowIdentify Enzyme In Tissue, The Test Involves Staining A Tissue Sample. If A Suspected Enzyme Is Present It Will Turn A Color Different From The Surrounding Tissue.

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 88319. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 88319 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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