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CPT 88355 Fee Schedule

Last Verified: October 2026

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Key FactDetail
Service Type

Pathology and Laboratory Procedures

Surgical Pathology Procedures

Common Place of Service

22 - On Campus Outpatient Hospital

81 - Independent Laboratory

Common Modifiers

None

26 - Professional component

59 - Distinct Procedural Service

Complexity LevelLow
Medicare Fee ScheduleView Medicare rates for 88355
Medicaid Fee ScheduleView Medicaid rates for 88355

National average reimbursement for CPT 88355 by major payers:

bcbs

$170.09

uhc

$151.49

aetna

$157.65

cigna

$167.49

CPT 88355 vs. Other Surgical Pathology Procedures Codes

The CPT 88355 code is part of the Pathology and Laboratory Procedures services used for Surgical Pathology Procedures. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The CPT 88355 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
88355-CPTLow
3-D Genetic Analysis Of Tissue, Genetic Material From A Tissue Sample Is Studied Using Morphometric Analysis A Technique For Learning About The Cause And Progression Of A Disease.
88356-CPTModerate
3-D Genetic Analysis Of Tissue, Genetic Material From A Tissue Sample Is Studied Using Morphometric Analysis A Technique For Learning About The Cause And Progression Of A Disease.
88358-CPTLow
Lab Exam Of Tumor Tissue, Cells From A Tumor Are Collected And Stained. They Are Examined Under A Microscope To Evaluate And Measure Their Structure Composition And Function.
88360-CPTLow
Tumor Immunohistochem Manual, Morphometric Analysis Tumor Immunohistochemistry Eg Her 2 Neu Estrogen Receptor Progesterone Receptor Quantitative Or Semiquantitative Per Specimen Each Single Antibody Stain Procedure Manual

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 88355. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the 88355 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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