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See a sample rate comparisonCPT 88364 Fee Schedule
Last Verified: October 2026
Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.
In Situ Hybridization (Eg Fis, In Situ Hybridization (Eg Fish) Per Specimen Each Additional Single Probe Stain Procedure (List Separately In Addition To Code For Primary Procedure)
| Key Fact | Detail |
|---|---|
| Service Type | Pathology and Laboratory Procedures Surgical Pathology Procedures |
| Common Place of Service | 22 - On Campus Outpatient Hospital 81 - Independent Laboratory |
| Common Modifiers | 26 - Professional component TC - Technical component |
| Complexity Level | Low |
| Medicare Fee Schedule | $126.59 national non-facility rate (2026) · View Medicare rates for 88364 |
| Medicaid Fee Schedule | $106.945 median of the 8 states in the free preview · View Medicaid rates for 88364 |
National average reimbursement for CPT 88364 by major payers:
$148.44
$104.80
$138.70
$144.49
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CPT 88364
5 of 25 sample ratesHigher to lower in this preview
Mustafa Al-Roubaie
H Lee Moffitt Cancer Ctr & Res Inst Life Time Cancer Scrn Ctr Inc
$168.13Published rateRiddhi Patel
H Lee Moffitt Cancer Ctr & Res Inst Life Time Cancer Scrn Ctr Inc
$142.91Published rateSam Vafadar
H Lee Moffitt Cancer Ctr & Res Inst Life Time Cancer Scrn Ctr Inc
$105.01Published rateReza Eshraghi
H Lee Moffitt Cancer Ctr & Res Inst Life Time Cancer Scrn Ctr Inc
$44.59Published rateSuhad Ali Mohammed
H Lee Moffitt Cancer Ctr & Res Inst Life Time Cancer Scrn Ctr Inc
$37.90Published rate
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See a sample payer proposalCPT 88364 vs. Other Surgical Pathology Procedures Codes
The CPT 88364 code is part of the Pathology and Laboratory Procedures services used for Surgical Pathology Procedures. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.
The CPT 88364 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.
| Code | Complexity | Description |
|---|---|---|
| 88362-CPT | Moderate | Nerve Teasing Preparations |
| 88363-CPT | Low | Examination And Selection Of R, Examination And Selection Of Retrieved Archival (Ie Previously Diagnosed) Tissue(S) For Molecular Analysis (Eg Kras Mutational Analysis) |
| 88364-CPT | Low | In Situ Hybridization (Eg Fis, In Situ Hybridization (Eg Fish) Per Specimen Each Additional Single Probe Stain Procedure (List Separately In Addition To Code For Primary Procedure) |
| 88365-CPT | Low | Study Of Genetic Risk Factor, The Study Identifies Genetic Abnormalities In Tissues That Can Be Linked With Cancers Or Other Changes In The Body. |
What is a fee schedule?
A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 88364. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.
Understanding the 88364 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.
Factors that affect fee schedules
Medicare & Medicaid Rates
Government-set reimbursement amounts
Private Insurance Rates
Negotiated rates between providers and insurance companies
Geographic Location
Costs may be higher in urban areas.
Provider Type
Hospital providers may have different rates than private practice.
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