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See a sample rate comparisonHealthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.
| Key Fact | Detail |
|---|---|
| Service Type | Pathology and Laboratory Procedures Surgical Pathology Procedures |
| Common Place of Service | 11 - Office 81 - Independent Laboratory 22 - On Campus Outpatient Hospital |
| Common Modifiers | 26 - Professional component |
| Complexity Level | Low |
| Medicare Fee Schedule | $45.09 national non-facility rate (2026) · View Medicare rates for 88375 |
| Medicaid Fee Schedule | $42.155 median of the 8 states in the free preview · View Medicaid rates for 88375 |
National average reimbursement for CPT 88375 by major payers:

$64.46

$42.30

$55.97

$92.12
Choose a payer to see a sample of rates for CPT 88375.
Chu Chen
Merrimack Valley Pediatric Associates, Inc.
Christopher Raio
St Joseph Hospital
Baycare Home Care, Inc.
Baycare Home Care Inc
Michael Jacobson
Hroa 401k Plan
Sunrise Home Health Care Inc.
Sunrise Home Health Care Inc
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Rate Benchmarking
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See a sample payer proposalCPT 88375 vs. Other Surgical Pathology Procedures Codes
The CPT 88375 code is part of the Pathology and Laboratory Procedures services used for Surgical Pathology Procedures. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.
The CPT 88375 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.
| Code | Complexity | Description |
|---|---|---|
| 88371-CPT | Low | Analysis Of Tissue Protein, This Test Detects Specific Proteins In A Sample Of Tissue. Analysis Of Specific Proteins Is Used To Help Diagnose Certain Diseases. |
| 88372-CPT | Low | Analysis Of Tissue Protein, This Test Detects Specific Proteins In A Sample Of Tissue. Analysis Of Specific Proteins Is Used To Help Diagnose Certain Diseases. |
| 88373-CPT | Low | M Phmtrc Alys Ishquant Semiq, Morphometric Analysis In Situ Hybridization Quantitative Or Semi Quantitative Using Computer Assisted Technology Per Specimen Each Additional Single Probe Stain Procedure List Separately In Addition To Code For Primary Procedure |
| 88375-CPT | Low | Examination With Scope, An Examination Using An Endoscope That Has A Microscope Attached For Taking Cellular Level Images (Endomicroscope). An Interpretation Of The Images And A Report Are Included. |
What is a fee schedule?
A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 88375. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.
Understanding the 88375 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.
Factors that affect fee schedules
Medicare & Medicaid Rates
Government-set reimbursement amounts
Private Insurance Rates
Negotiated rates between providers and insurance companies
Geographic Location
Costs may be higher in urban areas.
Provider Type
Hospital providers may have different rates than private practice.
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