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See a sample rate comparisonCPT 88399 Fee Schedule
Last Verified: October 2026
Healthcare providers use this code to document and receive reimbursement for visits that address high-level medical decision-making, often including multiple diagnoses or prescription management.
Pathology Exam Of Body Tissue, A Laboratory Study Of Tissue Organs Or Fluid Samples. A Pathology Study Detects Disease If It Is Present. The Sample May Be Removed During Surgery Or Another Procedure.
| Key Fact | Detail |
|---|---|
| Service Type | Pathology and Laboratory Procedures Surgical Pathology Procedures |
| Common Place of Service | 81 - Independent Laboratory 22 - On Campus Outpatient Hospital |
| Common Modifiers | TC - Technical component 26 - Professional component |
| Complexity Level | High |
| Medicare Fee Schedule | View Medicare rates for 88399 |
| Medicaid Fee Schedule | $39.885 median of the 2 states in the free preview · View Medicaid rates for 88399 |
National average reimbursement for CPT 88399 by major payers:
$1,234.87
$52.36
$7.59
$246.86
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CPT 88399
5 of 25 sample ratesHigher to lower in this preview
Lake Surgical Hospital Slidell, LLC
Lake Surgical Hospital Slidell, LLC Dba Southern Surgical Hospital
$83.12Published rateHouston Northwest Operating Company, LLC, Houston Northwest Medical Center Acute
$49.75Published rateVhs Harlingen Hospital Company LLC, Valley Baptist Medical Center
$49.75Published rateWest Jefferson Holdings, LLC, West Jefferson Medical Center
West Jefferson Holdings, LLC
$17.86Published rateTyler County Hospital District
$2.13Published rate
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Payer Contract Negotiation
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See a sample payer proposalCPT 88399 vs. Other Surgical Pathology Procedures Codes
The CPT 88399 code is part of the Pathology and Laboratory Procedures services used for Surgical Pathology Procedures. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.
The CPT 88399 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.
| Code | Complexity | Description |
|---|---|---|
| 87999-CPT | Moderate | Microorganism Analysis, Test To Identify Microorganisms. Methods Range From Viewing A Sample With A Microscope To Dividing A Sample Into Parts And Running A Different Test On Each One. |
| 88360-CPT | Low | Tumor Immunohistochem Manual, Morphometric Analysis Tumor Immunohistochemistry Eg Her 2 Neu Estrogen Receptor Progesterone Receptor Quantitative Or Semiquantitative Per Specimen Each Single Antibody Stain Procedure Manual |
| 88387-CPT | Low | Tiss Exam Molecular Study, Macroscopic Examination Dissection And Preparation Of Tissue For Non Microscopic Analytical Studies Eg Nucleic Acid Based Molecular Studies Each Tissue Preparation Eg A Single Lymph Node |
| 88399-CPT | High | Pathology Exam Of Body Tissue, A Laboratory Study Of Tissue Organs Or Fluid Samples. A Pathology Study Detects Disease If It Is Present. The Sample May Be Removed During Surgery Or Another Procedure. |
What is a fee schedule?
A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 88399. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.
Understanding the 88399 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.
Factors that affect fee schedules
Medicare & Medicaid Rates
Government-set reimbursement amounts
Private Insurance Rates
Negotiated rates between providers and insurance companies
Geographic Location
Costs may be higher in urban areas.
Provider Type
Hospital providers may have different rates than private practice.
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