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See a sample rate comparisonCPT 90281 Fee Schedule
Last Verified: October 2026
Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.
Human Immune Globulin, Human Immune Globulin Is Derived From Blood Products And Is Typically Given As A Shot Through An Iv Or Under The Skin With Fluids.
| Key Fact | Detail |
|---|---|
| Service Type | Medicine Services and Procedures Immune Globulins, Serum or Recombinant Products |
| Common Place of Service | 11 - Office 21 - Inpatient Hospital |
| Common Modifiers | GA - Required ABN issued and on file 25 - Significant, separately identifiable E/M service same day |
| Complexity Level | Low |
| Medicare Fee Schedule | View Medicare rates for 90281 |
| Medicaid Fee Schedule | $26.88 median of the 7 states in the free preview · View Medicaid rates for 90281 |
National average reimbursement for CPT 90281 by major payers:
$100.51
$108.42
$103.05
$105.79
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CPT 90281
5 of 25 sample ratesHigher to lower in this preview
Chu Chen
Merrimack Valley Pediatric Associates, Inc.
$215.45Published rateNitin Patel
$117.51Published rateCharles Marcuccilli
$109.68Published rateJoseph Pepitone
Northshore University Healthsystem Faculty Practice Associates
$107.72Published rateRestorative Health Rehabilitation Inc
$55.00Published rate
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See a sample payer proposalCPT 90281 vs. Other Immune Globulins, Serum or Recombinant Products Codes
The CPT 90281 code is part of the Medicine Services and Procedures services used for Immune Globulins, Serum or Recombinant Products. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.
The CPT 90281 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.
| Code | Complexity | Description |
|---|---|---|
| 90281-CPT | Low | Human Immune Globulin, Human Immune Globulin Is Derived From Blood Products And Is Typically Given As A Shot Through An Iv Or Under The Skin With Fluids. |
| 90283-CPT | Low | Human Immune Globulin, Human Immune Globulin Is Derived From Blood Products And Is Typically Given As A Shot Through An Iv Or Under The Skin With Fluids. |
| 90284-CPT | Low | Human Immune Globulin, Human Immune Globulin Is Derived From Blood Products And Is Typically Given As A Shot Through An Iv Or Under The Skin With Fluids. |
| 90371-CPT | Low | Hepatitis B Immunity Solution, An Antibody Substance (Gamma Globulin Or Immune Globulin) That Helps To Prevent Infection By The Hepatitis B Virus Which Causes A Serious Liver Infection. |
What is a fee schedule?
A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including CPT 90281. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.
Understanding the 90281 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.
Factors that affect fee schedules
Medicare & Medicaid Rates
Government-set reimbursement amounts
Private Insurance Rates
Negotiated rates between providers and insurance companies
Geographic Location
Costs may be higher in urban areas.
Provider Type
Hospital providers may have different rates than private practice.
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