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See a sample rate comparisonHCPCS A4221 Fee Schedule
Last Verified: September 2026
Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.
Supplies for maintenance of non-insulin drug infusion catheter, per week (list drugs separately)
| Key Fact | Detail |
|---|---|
| Service Type | Medical And Surgical Supplies Injection and Infusion Supplies |
| Complexity Level | Low |
| Medicaid Fee Schedule | View Medicaid rates for A4221 |
National average reimbursement for HCPCS A4221 by major payers:
$21.24
$15.61
$18.35
$30.14
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HCPCS A4221
5 of 25 sample ratesHigher to lower in this preview
Frank Winsett
$22.03Published rateDonald Glass
$21.65Published rateVital Rangashamanna
$14.26Published rateHigh Country Community Rural Health Clinic
$11.83Published rateEmily Prosise
Central Texas Dermatology, PA
$10.96Published rate
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See a sample payer proposalHCPCS A4221 vs. Other Injection and Infusion Supplies Codes
The HCPCS A4221 code is part of the Medical And Surgical Supplies services used for Injection and Infusion Supplies. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.
The HCPCS A4221 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.
| Code | Complexity | Description |
|---|---|---|
| A4220-HCPCS | Low | Refill kit for implantable infusion pump |
| A4221-HCPCS | Low | Supplies for maintenance of non-insulin drug infusion catheter, per week (list drugs separately) |
| A4222-HCPCS | Low | Infusion supplies for external drug infusion pump, per cassette or bag (list drugs separately) |
What is a fee schedule?
A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including HCPCS A4221. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.
Understanding the A4221 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.
Factors that affect fee schedules
Medicare & Medicaid Rates
Government-set reimbursement amounts
Private Insurance Rates
Negotiated rates between providers and insurance companies
Geographic Location
Costs may be higher in urban areas.
Provider Type
Hospital providers may have different rates than private practice.
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