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HCPCS G0481 Fee Schedule

Medicare rates as of January 2026

HCPCS G0481 is classified under Procedures / Professional Services, in the Other Services subgroup.

Drug test(s), definitive, utilizing (1) drug identification methods able to identify individual drugs and distinguish between structural isomers (but not necessarily stereoisomers), including, but not limited to GC/MS (any type, single or tandem) and LC/MS (any type, single or tandem and excluding immunoassays (e.g., IA, EIA, ELISA, EMIT, FPIA) and enzymatic methods (e.g., alcohol dehydrogenase)), (2) stable isotope or other universally recognized internal standards in all samples (e.g., to control for matrix effects, interferences and variations in signal strength), and (3) method or drug-specific calibration and matrix-matched quality control material (e.g., to control for instrument variations and mass spectral drift); qualitative or quantitative, all sources, includes specimen validity testing, per day; 8-14 drug class(es), including metabolite(s) if performed
Key FactDetail
Service Type

Procedures / Professional Services

Other Services

Common Revenue Codes03000301Sign up to view all 4
Medicare Fee Schedule$156.59 national lab fee schedule rate (2026)View Medicare rates for G0481
Medicaid Fee Schedule$153.07 median of the 8 states in the free previewView Medicaid rates for G0481

National average reimbursement for HCPCS G0481 by major payers:

BCBS / Anthem logo

$110.55

BCBS / Anthem

UnitedHealthcare logo

$85.91

UnitedHealthcare

Aetna logo

$150.36

Aetna

Cigna logo

$136.14

Cigna

Compare published rates across providers.

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HCPCS G0481
5 of 25 sample ratesHigher to lower in this preview
  1. Gary Cundiff

    Consultants In Pain Management, P.C.

    TNPsychologistNPI 1356302061Tax ID 30-0070474

    $172.25Published rate
  2. Dana Simpson

    Consultants In Pain Management, P.C.

    TNFamily Nurse PractitionerNPI 1114253689Tax ID 30-0070474

    $65.76Published rate
  3. Rachel Kimble

    Consultants In Pain Management, P.C.

    TNNurse PractitionerNPI 1033532429Tax ID 30-0070474

    $65.76Published rate
  4. Jeffrey Brown

    Ut Regional One Physicians Inc

    TNAnesthesiology PhysicianNPI 1568676195Tax ID 47-1157530

    $61.50Published rate
  5. Georgia Pain Physicians PC, Knoxville Pain Management

    Georgia Pain Physicians

    TNPain Medicine PhysicianNPI 1841697950Tax ID 58-2318726

    $24.54Published rate

National sample. Rates vary by location, specialty, and contract.

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HCPCS G0481 vs. Other Other Services Codes

The table lists codes related to G0481. Select one to see its fee schedule.

CodeDescription
G0480-HCPCSDrug test(s), definitive, utilizing (1) drug identification methods able to identify individual drugs and distinguish between structural isomers (but not necessarily stereoisomers), including, but not limited to GC/MS (any type, single or tandem) and LC/MS (any type, single or tandem and excluding immunoassays (e.g., IA, EIA, ELISA, EMIT, FPIA) and enzymatic methods (e.g., alcohol dehydrogenase)), (2) stable isotope or other universally recognized internal standards in all samples (e.g., to control for matrix effects, interferences and variations in signal strength), and (3) method or drug-specific calibration and matrix-matched quality control material (e.g., to control for instrument variations and mass spectral drift); qualitative or quantitative, all sources, includes specimen validity testing, per day; 1-7 drug class(es), including metabolite(s) if performed
G0481-HCPCSDrug test(s), definitive, utilizing (1) drug identification methods able to identify individual drugs and distinguish between structural isomers (but not necessarily stereoisomers), including, but not limited to GC/MS (any type, single or tandem) and LC/MS (any type, single or tandem and excluding immunoassays (e.g., IA, EIA, ELISA, EMIT, FPIA) and enzymatic methods (e.g., alcohol dehydrogenase)), (2) stable isotope or other universally recognized internal standards in all samples (e.g., to control for matrix effects, interferences and variations in signal strength), and (3) method or drug-specific calibration and matrix-matched quality control material (e.g., to control for instrument variations and mass spectral drift); qualitative or quantitative, all sources, includes specimen validity testing, per day; 8-14 drug class(es), including metabolite(s) if performed
G0482-HCPCSDrug test(s), definitive, utilizing (1) drug identification methods able to identify individual drugs and distinguish between structural isomers (but not necessarily stereoisomers), including, but not limited to GC/MS (any type, single or tandem) and LC/MS (any type, single or tandem and excluding immunoassays (e.g., IA, EIA, ELISA, EMIT, FPIA) and enzymatic methods (e.g., alcohol dehydrogenase)), (2) stable isotope or other universally recognized internal standards in all samples (e.g., to control for matrix effects, interferences and variations in signal strength), and (3) method or drug-specific calibration and matrix-matched quality control material (e.g., to control for instrument variations and mass spectral drift); qualitative or quantitative, all sources, includes specimen validity testing, per day; 15-21 drug class(es), including metabolite(s) if performed

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including HCPCS G0481. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the G0481 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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Frequently Asked Questions

Which revenue codes are billed with HCPCS G0481?


Hospital price transparency files list HCPCS G0481 under these revenue codes: 0300, 0301, 0309 and 0971. A revenue code names the hospital department or charge category for the line; it does not change what the service is.

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