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HCPCS G0480 Fee Schedule

Medicare rates as of January 2026

HCPCS G0480 is classified under Procedures / Professional Services, in the Other Services subgroup.

Drug test(s), definitive, utilizing (1) drug identification methods able to identify individual drugs and distinguish between structural isomers (but not necessarily stereoisomers), including, but not limited to GC/MS (any type, single or tandem) and LC/MS (any type, single or tandem and excluding immunoassays (e.g., IA, EIA, ELISA, EMIT, FPIA) and enzymatic methods (e.g., alcohol dehydrogenase)), (2) stable isotope or other universally recognized internal standards in all samples (e.g., to control for matrix effects, interferences and variations in signal strength), and (3) method or drug-specific calibration and matrix-matched quality control material (e.g., to control for instrument variations and mass spectral drift); qualitative or quantitative, all sources, includes specimen validity testing, per day; 1-7 drug class(es), including metabolite(s) if performed
Key FactDetail
Service Type

Procedures / Professional Services

Other Services

Common Revenue Codes03000301Sign up to view all 4
Medicare Fee Schedule$114.43 national lab fee schedule rate (2026)View Medicare rates for G0480
Medicaid Fee Schedule$111.855 median of the 8 states in the free previewView Medicaid rates for G0480

National average reimbursement for HCPCS G0480 by major payers:

BCBS / Anthem logo

$80.07

BCBS / Anthem

UnitedHealthcare logo

$60.53

UnitedHealthcare

Aetna logo

$100.13

Aetna

Cigna logo

$99.24

Cigna

Compare published rates across providers.

Choose a payer to see a sample of rates for HCPCS G0480.

HCPCS G0480
5 of 25 sample ratesHigher to lower in this preview
  1. Mike Perez

    Baylor College Of Medicine

    TXClinical Pathology PhysicianNPI 1194929778Tax ID 76-0421006

    $343.29Published rate
  2. Esoterix, Inc

    TXClinical Medical LaboratoryNPI 1902883077Tax ID 13-3802358

    $84.69Published rate
  3. Larry Cartmell

    Waco Pathology Associates PA

    TXAnatomic Pathology & Clinical Pathology PhysicianNPI 1952312605Tax ID 74-2870172

    $68.66Published rate
  4. Trincare Inc, Trincare Clinical Laboratories

    TXClinical Medical LaboratoryNPI 1033351226Tax ID 75-2161369

    $51.49Published rate
  5. Roshan Raza

    Baylor College Of Medicine

    TXAnatomic Pathology & Clinical Pathology PhysicianNPI 1225423502Tax ID 74-1613878

    $33.56Published rate

National sample. Rates vary by location, specialty, and contract.

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HCPCS G0480 vs. Other Other Services Codes

The table lists codes related to G0480. Select one to see its fee schedule.

CodeDescription
G0476-HCPCSInfectious agent detection by nucleic acid (dna or rna); human papillomavirus (hpv), high-risk types (eg, 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 68) for cervical cancer screening, must be performed in addition to pap test
G0480-HCPCSDrug test(s), definitive, utilizing (1) drug identification methods able to identify individual drugs and distinguish between structural isomers (but not necessarily stereoisomers), including, but not limited to GC/MS (any type, single or tandem) and LC/MS (any type, single or tandem and excluding immunoassays (e.g., IA, EIA, ELISA, EMIT, FPIA) and enzymatic methods (e.g., alcohol dehydrogenase)), (2) stable isotope or other universally recognized internal standards in all samples (e.g., to control for matrix effects, interferences and variations in signal strength), and (3) method or drug-specific calibration and matrix-matched quality control material (e.g., to control for instrument variations and mass spectral drift); qualitative or quantitative, all sources, includes specimen validity testing, per day; 1-7 drug class(es), including metabolite(s) if performed
G0481-HCPCSDrug test(s), definitive, utilizing (1) drug identification methods able to identify individual drugs and distinguish between structural isomers (but not necessarily stereoisomers), including, but not limited to GC/MS (any type, single or tandem) and LC/MS (any type, single or tandem and excluding immunoassays (e.g., IA, EIA, ELISA, EMIT, FPIA) and enzymatic methods (e.g., alcohol dehydrogenase)), (2) stable isotope or other universally recognized internal standards in all samples (e.g., to control for matrix effects, interferences and variations in signal strength), and (3) method or drug-specific calibration and matrix-matched quality control material (e.g., to control for instrument variations and mass spectral drift); qualitative or quantitative, all sources, includes specimen validity testing, per day; 8-14 drug class(es), including metabolite(s) if performed

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including HCPCS G0480. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the G0480 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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Frequently Asked Questions

Which revenue codes are billed with HCPCS G0480?


Hospital price transparency files list HCPCS G0480 under these revenue codes: 0300, 0301, 0309 and 0971. A revenue code names the hospital department or charge category for the line; it does not change what the service is.

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