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HCPCS J0218 (Xenpozyme) Fee Schedule

Last Verified: November 2025

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Injection, olipudase alfa-rpcp, 1 mg
Key FactDetail
Service Type

Drugs Administered Other than Oral Method

Drugs, Administered by Injection

Common Place of Service

None

11 - Office

Complexity LevelModerate
Medicare Payment Limit
$393.661BuyandBill.com
WAC Price
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Related NDC Codes

58468-0050-01 - XENPOZYME (SDV,PF,LATEX-FREE) 20 MG


National average reimbursement for HCPCS J0218 by major payers:

bcbs

$370.43

uhc

$390.50

aetna

$413.12

cigna

$404.57

Preview provider-level rates for...
For billing codeHCPCS J0218
PayerCodeRateNPITax IDStateSpecialty

Select a payer to view fee schedule data

Choose a payer from the options above to see rates for HCPCS J0218

United
J0218$382.551477502946 - SEATTLE VAMC, TACOMA VAMC910565166WAGeneral Acute Care Hospital (282N00000X)
United
J0218$382.551245257880 - MCLAREN THUMB REGION, HURON MEDICAL CENTER381474929 - (MI) HURON MEMORIAL HOSPITALMIGeneral Acute Care Hospital (282N00000X)
United
J0218$382.551801893417 - SMITHVILLE HOSPITAL AUTHORITY, SMITHVILLE REGIONAL HOSPITAL741706734TXGeneral Acute Care Hospital (282N00000X)
United
J0218$381.821396764080 - DECATUR GENERAL HOSPITAL, THE HEALTHCARE AUTHORITY OF MORGAN COUNTY636000260ALGeneral Acute Care Hospital (282N00000X)
United
J0218$252.221669703245 - RUI DOMINGUES132655001 - NEW YORK CITY HEALTH AND HOSPITALS CORPORATIONNYGeneral Acute Care Hospital (282N00000X)
United
J0218$195.111679663835 - CAROLE DUBUCHE132828349 - SUN RIVER HEALTH INCNYGeneral Acute Care Hospital (282N00000X)
United
J0218$404.471134273170 - DUNSTAN ABRAHAM61578286 - DOWNTOWN BRONX MEDICAL ASSOCIATES PCNYGeneral Acute Care Hospital (282N00000X)
United
J0218$505.351386175560 - NARGIS JILANI112558775 - (NY) STONY BROOK INTERNISTS P CNYGeneral Acute Care Hospital (282N00000X)
United
J0218$382.551306184916 - MARYAMNAZ FALAMAKI760010407NYGeneral Acute Care Hospital (282N00000X)
United
J0218$382.551801830500 - TRIAD OF ALABAMA LLC, FLOWERS HOSPITAL621762412 - (AL) TRIAD OF ALABAMA LLCALGeneral Acute Care Hospital (282N00000X)
United
J0218$299.921679697544 - AMMAR NASSER-EDDIN132655001 - NEW YORK CITY HEALTH AND HOSPITALS CORPORATIONNYGeneral Acute Care Hospital (282N00000X)
United
J0218$348.131245274901 - ST. AGNES HEALTHCARE, INC., ST.AGNES HOSPITAL520591657 - ST AGNES HEALTHCARE INCMDGeneral Acute Care Hospital (282N00000X)
United
J0218$553.281669423380 - MAINEGENERAL MEDICAL CENTER43369653 - MAINEGENERAL HEALTHMEGeneral Acute Care Hospital (282N00000X)
United
J0218$382.551609825702 - BUFFALO VAMC, BATH VAMC161447141NYGeneral Acute Care Hospital (282N00000X)
United
J0218$385.391164485363 - ST MARY MEDICAL CENTER, OSF SAINT MARY MEDICAL CENTER370662581ILGeneral Acute Care Hospital (282N00000X)
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist

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HCPCS J0218 vs. Other Drugs, Administered by Injection Codes

The HCPCS J0218 code is part of the Drugs Administered Other than Oral Method services used for Drugs, Administered by Injection. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The HCPCS J0218 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
58468-0050-01-NDCModerateXENPOZYME (SDV,PF,LATEX-FREE) 20 MG
J0216-HCPCSLowInjection, alfentanil hydrochloride, 500 micrograms
J0218-HCPCSModerateInjection, olipudase alfa-rpcp, 1 mg
J0219-HCPCSLowInjection, avalglucosidase alfa-ngpt, 4 mg

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including HCPCS J0218. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the J0218 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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