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HCPCS J0218 (Xenpozyme) Fee Schedule

Last Verified: January 2026

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Injection, olipudase alfa-rpcp, 1 mg
Key FactDetail
Service Type

Drugs Administered Other than Oral Method

Drugs, Administered by Injection

Common Place of Service

None

11 - Office

Complexity LevelModerate
Medicare Payment Limit
$393.661BuyandBill.com
WAC Price
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Related NDC Codes

58468-0050-01 - XENPOZYME (SDV,PF,LATEX-FREE) 20 MG


National average reimbursement for HCPCS J0218 by major payers:

bcbs

$370.43

uhc

$390.50

aetna

$413.12

cigna

$404.57

Preview provider-level rates for...
For billing codeHCPCS J0218
PayerCodeRateNPITax IDStateSpecialty

Select a payer to view fee schedule data

Choose a payer from the options above to see rates for HCPCS J0218

United
J0218$735.091467406132 - EASTSIDE MEDICAL CENTER, LLC, PIEDMONT EASTSIDE MEDICAL CENTER582433432GAGeneral Acute Care Hospital (282N00000X)
United
J0218$553.051134550239 - MARKUS PLATE131623978NYGeneral Acute Care Hospital (282N00000X)
United
J0218$639.591588662357 - ALTOONA REGIONAL HEALTH SYSTEM, ALTOONA REGIONAL HEALTH SYSTEM231352155 - UPMCPAGeneral Acute Care Hospital (282N00000X)
United
J0218$381.571710920327 - BLANCHARD VALLEY REGIONAL HEALTH CENTER, BLANCHARD VALLEY HOSPITAL341369963 - (OH) BLANCHARD VALLEY REGIONAL HEALTH CENTEROHGeneral Acute Care Hospital (282N00000X)
United
J0218$877.541538123567 - ALLINA HEALTH SYSTEM, BUFFALO HOSPITAL363261413 - ALLINA HEALTH SYSTEMMNGeneral Acute Care Hospital (282N00000X)
United
J0218$381.821811006661 - SOUTHEAST HOSPITAL, MERCY HOSPITAL SOUTHEAST430654874 - (MO) SOUTHEAST HOSPITALMOGeneral Acute Care Hospital (282N00000X)
United
J0218$382.551447571658 - SUMNER REGIONAL MEDICAL CENTER LLC, SUMNER REGIONAL MEDICAL CENTER272618766TNGeneral Acute Care Hospital (282N00000X)
United
J0218$382.551396132585 - MA MOE263381883 - AMBOY MEDICAL PRACTICE PCNYGeneral Acute Care Hospital (282N00000X)
United
J0218$637.961649278730 - UPMC ALTOONA231352155 - UPMCPAGeneral Acute Care Hospital (282N00000X)
United
J0218$1726.231316165814 - NEO-PERINATOLOGY ASSOCIATES OF ORANGE COUNTY, UCI MEDICAL CENTER954105559CAGeneral Acute Care Hospital (282N00000X)
United
J0218$381.571942271671 - ST JOHN OAKLAND HOSPITAL383322109 - ASCENSION MACOMB OAKLAND HOSPITALMIGeneral Acute Care Hospital (282N00000X)
United
J0218$382.551780648352 - BAPTIST MEMORIAL HOSPITAL UNION COUNTY, INC.630997281 - (MS) BAPTIST MEMORIAL HOSPITAL UNION COUNTY INCMSGeneral Acute Care Hospital (282N00000X)
United
J0218$299.161205020534 - QIUHUA LU132655001 - NEW YORK CITY HEALTH AND HOSPITALS CORPORATIONNYGeneral Acute Care Hospital (282N00000X)
United
J0218$404.471306930318 - IRA DAVENPORT MEMORIAL HOSPITAL, INC.160835446 - (NY) IRA DAVENPORT MEMORIAL HOSPITAL INCNYGeneral Acute Care Hospital (282N00000X)
United
J0218$382.551407191984 - BSA HOSPITAL LLC300754305TXGeneral Acute Care Hospital (282N00000X)
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist
United
99202$100.0012345678901234567890CACardiologist

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HCPCS J0218 vs. Other Drugs, Administered by Injection Codes

The HCPCS J0218 code is part of the Drugs Administered Other than Oral Method services used for Drugs, Administered by Injection. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The HCPCS J0218 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
58468-0050-01-NDCModerateXENPOZYME (SDV,PF,LATEX-FREE) 20 MG
J0216-HCPCSLowInjection, alfentanil hydrochloride, 500 micrograms
J0218-HCPCSModerateInjection, olipudase alfa-rpcp, 1 mg
J0219-HCPCSLowInjection, avalglucosidase alfa-ngpt, 4 mg

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including HCPCS J0218. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the J0218 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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