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HCPCS J0218 (Xenpozyme) Fee Schedule

Last Verified: October 2026

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Injection, olipudase alfa-rpcp, 1 mg
Key FactDetail
Service Type

Drugs Administered Other than Oral Method

Drugs, Administered by Injection

Common Place of Service

None

11 - Office

Complexity LevelModerate
Medicaid Fee ScheduleView Medicaid rates for J0218
Medicare Payment Limit
$393.661BuyandBill.com
WAC Price
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Related NDC Codes

• 58468-0050-01 - XENPOZYME (SDV,PF,LATEX-FREE) 20 MG


National average reimbursement for HCPCS J0218 by major payers:

bcbs

$370.43

uhc

$390.50

aetna

$413.12

cigna

$404.57

Compare published rates across providers.

Choose a payer to see a sample of rates for HCPCS J0218.

HCPCS J0218
5 of 25 sample ratesHigher to lower in this preview
  1. Neo-Perinatology Associates Of Orange County, Uci Medical Center

    CAGeneral Acute Care HospitalNPI 1316165814Tax ID 95-4105559

    $1,726.23Published rate
  2. Adam Iwanski

    The Everett Clinic, PLLC

    ILGeneral Acute Care HospitalNPI 1548678527Tax ID 91-0214500

    $629.60Published rate
  3. Sumner Regional Medical Center LLC, Sumner Regional Medical Center

    TNGeneral Acute Care HospitalNPI 1447571658Tax ID 27-2618766

    $382.55Published rate
  4. Blanchard Valley Regional Health Center, Blanchard Valley Hospital

    Blanchard Valley Regional Health Center

    OHGeneral Acute Care HospitalNPI 1710920327Tax ID 34-1369963

    $381.57Published rate
  5. Zachary Macdonald

    New York City Health And Hospitals Corporation

    NYGeneral Acute Care HospitalNPI 1851755201Tax ID 13-2655001

    $299.16Published rate

National sample. Rates vary by location, specialty, and contract.

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HCPCS J0218 vs. Other Drugs, Administered by Injection Codes

The HCPCS J0218 code is part of the Drugs Administered Other than Oral Method services used for Drugs, Administered by Injection. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The HCPCS J0218 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
58468-0050-01-NDCModerateXENPOZYME (SDV,PF,LATEX-FREE) 20 MG
J0216-HCPCSLowInjection, alfentanil hydrochloride, 500 micrograms
J0218-HCPCSModerateInjection, olipudase alfa-rpcp, 1 mg
J0219-HCPCSLowInjection, avalglucosidase alfa-ngpt, 4 mg

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including HCPCS J0218. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the J0218 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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