HCPCS J0221 (Lumizyme) Fee Schedule
Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.
| Key Fact | Detail |
|---|---|
| Service Type | • Drugs Administered Other than Oral Method • Drugs, Administered by Injection |
| Common Place of Service | • None • 99 - Other POS |
| Complexity Level | Moderate |
| Medicare Payment Limit | |
| WAC Price | Lorem ipsum dolor sit amet consectetur Lorem ipsum dolor sit amet consectetur VisitBuyandBill.com |
National average reimbursement for HCPCS J0221 by major payers:

$218.98

$206.61

$218.04

$214.16
| Payer | Code | Rate | NPI | Tax ID | State | Specialty |
|---|---|---|---|---|---|---|
Select a payer to view fee schedule data Choose a payer from the options above to see rates for HCPCS J0221 | ||||||
United | J0221 | $234.35 | 1316137201 - MEDSTAR GEORGETOWN MEDICAL CENTER, INC, GEORGETOWN UNIVERSITY HOSPITAL PHYSICIANS | 522218584 - (DC) MEDSTAR-GEORGETOWN MEDICAL CENTER INC | DC | General Acute Care Hospital (282N00000X) |
United | J0221 | $201.63 | 1558637017 - ST. JOSEPH REGIONAL MEDICAL CENTER, ST. JOSEPH MEDICAL GROUP | 364851166 | ID | General Acute Care Hospital (282N00000X) |
United | J0221 | $213.74 | 1851777585 - WAJEEHA SAEED | 900603487 - (NY) PHYSICIAN AFFILIATE GROUP OF NEW YORK PC | NY | General Acute Care Hospital (282N00000X) |
United | J0221 | $208.39 | 1598127359 - SARAH PHILIPS | 743039276 - CHEN & MORGAN OBGYN WESTSIDE PLLC | NY | General Acute Care Hospital (282N00000X) |
United | J0221 | $201.63 | 1043878325 - ARH TUG VALLEY HEALTH SERVICES, INC., HIGHLANDS ARH REGIONAL MEDICAL CENTER | 202470645 | KY | General Acute Care Hospital (282N00000X) |
United | J0221 | $207.69 | 1255785069 - ROSALYN GAMBOA | 133278552 - (NY) MEMORIAL CARDIOPULMONARY GROUP | NY | General Acute Care Hospital (282N00000X) |
United | J0221 | $214.08 | 1346369212 - NEWARK WAYNE COMMUNITY HOSPITAL, NEWARK WAYNE COMM - PROF | 150584188 - (NY) NEWARK WAYNE COMMUNITY HOSPITAL | NY | General Acute Care Hospital (282N00000X) |
United | J0221 | $133.27 | 1851777585 - WAJEEHA SAEED | 132655001 - NEW YORK CITY HEALTH AND HOSPITALS CORPORATION | NY | General Acute Care Hospital (282N00000X) |
United | J0221 | $188.39 | 1720028772 - BROOKDALE HOSPITAL MEDICAL CENTER | 111631746 - BROOKDALE HOSPITAL MEDICAL CENTER | NY | General Acute Care Hospital (282N00000X) |
United | J0221 | $201.97 | 1861492084 - TRINITAS REGIONAL MEDICAL CENTER, TRINITAS HOSPITAL - CPI | 223601678 - (NJ) RWJ BARNABAS HEALTH INC | NJ | General Acute Care Hospital (282N00000X) |
United | J0221 | $201.63 | 1104956358 - KALEIDA HEALTH, DEGRAFF HOSPITAL | 161533232 - KALEIDA HEALTH | NY | General Acute Care Hospital (282N00000X) |
United | J0221 | $463.29 | 1457319485 - ALLINA HEALTH SYSTEM, UNITED HOSPITAL | 363261413 - ALLINA HEALTH SYSTEM | MN | General Acute Care Hospital (282N00000X) |
United | J0221 | $214.08 | 1972965861 - CHRISTINA CIRACO | 132655001 - NEW YORK CITY HEALTH AND HOSPITALS CORPORATION | NY | General Acute Care Hospital (282N00000X) |
United | J0221 | $201.63 | 1851336044 - ST. JOSEPHS COMMUNITY HOSPITAL OF WEST BEND INC., FROEDTERT WEST BEND HOSPITAL | 391896819 - WISCONSIN DIAGNOSTIC LABORATORIES LLC | WI | General Acute Care Hospital (282N00000X) |
United | J0221 | $201.63 | 1336589753 - VIJAY KODADHALA | 454832340 | MD | General Acute Care Hospital (282N00000X) |
United | 99202 | $100.00 | 1234567890 | 1234567890 | CA | Cardiologist |
United | 99202 | $100.00 | 1234567890 | 1234567890 | CA | Cardiologist |
United | 99202 | $100.00 | 1234567890 | 1234567890 | CA | Cardiologist |
United | 99202 | $100.00 | 1234567890 | 1234567890 | CA | Cardiologist |
United | 99202 | $100.00 | 1234567890 | 1234567890 | CA | Cardiologist |
United | 99202 | $100.00 | 1234567890 | 1234567890 | CA | Cardiologist |
United | 99202 | $100.00 | 1234567890 | 1234567890 | CA | Cardiologist |
United | 99202 | $100.00 | 1234567890 | 1234567890 | CA | Cardiologist |
United | 99202 | $100.00 | 1234567890 | 1234567890 | CA | Cardiologist |
United | 99202 | $100.00 | 1234567890 | 1234567890 | CA | Cardiologist |
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HCPCS J0221 vs. Other Drugs, Administered by Injection Codes
The HCPCS J0221 code is part of the Drugs Administered Other than Oral Method services used for Drugs, Administered by Injection. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.
The HCPCS J0221 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.
| Code | Complexity | Description |
|---|---|---|
| J0220-HCPCS | Low | Injection, alglucosidase alfa, 10 mg, not otherwise specified |
| J0221-HCPCS | Moderate | Injection, alglucosidase alfa, (Lumizyme), 10 mg |
| J0222-HCPCS | Low | Injection, Patisiran, 0.1 mg |
What is a fee schedule?
A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including HCPCS J0221. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.
Understanding the J0221 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.
Factors that affect fee schedules
Medicare & Medicaid Rates
Government-set reimbursement amounts
Private Insurance Rates
Negotiated rates between providers and insurance companies
Geographic Location
Costs may be higher in urban areas.
Provider Type
Hospital providers may have different rates than private practice.
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