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HCPCS J2323 (Tysabri) Fee Schedule

Last Verified: October 2026

Healthcare providers use this code to document and receive reimbursement for visits that address moderate-level medical decision-making, often including multiple diagnoses or prescription management.

Injection, natalizumab, 1 mg
Key FactDetail
Service Type

Drugs Administered Other than Oral Method

Drugs, Administered by Injection

Common Place of Service

11 - Office

Complexity LevelLow
Medicare Fee Schedule$23.93 per 1 mg (October 2026 ASP) · View Medicare rates for J2323
Medicaid Fee Schedule$24.405 median of the 8 states in the free preview · View Medicaid rates for J2323
Medicare Payment Limit
$23.996BuyandBill.com
WAC Price
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National average reimbursement for HCPCS J2323 by major payers:

bcbs

$26.67

uhc

$24.96

aetna

$26.67

cigna

$25.79

Compare published rates across providers.

Choose a payer to see a sample of rates for HCPCS J2323.

HCPCS J2323
5 of 25 sample ratesHigher to lower in this preview
  1. Sangeetha Radhakrishnan

    Kelsey-Seybold Medical Group PLLC

    TXInternal Medicine PhysicianNPI 1770726259Tax ID 76-0386391

    $70.66Published rate
  2. Kelsey Richardson

    Covenant Medical Group

    TXFamily Medicine PhysicianNPI 1558717876Tax ID 75-2743883

    $24.45Published rate
  3. John Cunningham

    Gastroenterology Consultants Of San Antonio, P.A.

    TXGastroenterology PhysicianNPI 1578686507Tax ID 74-1967809

    $24.22Published rate
  4. James Prescott

    William Newton Memorial Hospital

    KSFamily Medicine PhysicianNPI 1548352644Tax ID 48-6005089

    $24.06Published rate
  5. Specialists Hospital Shreveport, LLC

    Specialists Hospital Shreveport, L.L.C.

    LAGeneral Acute Care HospitalNPI 1104057694Tax ID 20-8810573

    $23.87Published rate

National sample. Rates vary by location, specialty, and contract.

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HCPCS J2323 vs. Other Drugs, Administered by Injection Codes

The HCPCS J2323 code is part of the Drugs Administered Other than Oral Method services used for Drugs, Administered by Injection. It represents a moderate-complexity encounter and is one of several codes that vary based on time spent, level of medical decision-making, and documentation requirements.

The HCPCS J2323 code involves more provider time and moderate medical decision-making, unlike lower-level codes that require less time and simpler assessments. It typically includes multiple diagnoses, medication management, or test interpretation, leading to higher reimbursement and more detailed documentation requirements.

CodeComplexityDescription
J2320-HCPCSLowInjection, nandrolone decanoate, up to 50 mg
J2323-HCPCSLowInjection, natalizumab, 1 mg
J2325-HCPCSLowInjection, nesiritide, 0.1 mg

What is a fee schedule?

A fee schedule is a list of fixed prices that healthcare providers charge for specific services, including HCPCS J2323. These prices vary depending on payer type (Medicare, Medicaid, private insurance), geographic location, and provider contracts.

Understanding the J2323 fee schedule helps patients estimate costs and providers optimize billing for accurate reimbursements.

Factors that affect fee schedules


Medicare & Medicaid Rates

Government-set reimbursement amounts


Private Insurance Rates

Negotiated rates between providers and insurance companies


Geographic Location

Costs may be higher in urban areas.


Provider Type

Hospital providers may have different rates than private practice.

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